E3 ubiquitin-protein ligase HECW2 isoform X2 [Stomoxys calcitrans].

LOCUS       XP_013103283             434 aa            linear   INV 02-SEP-2023
ACCESSION   XP_013103283
VERSION     XP_013103283.1
DBLINK      BioProject: PRJNA1009844
DBSOURCE    REFSEQ: accession XM_013247829.2
KEYWORDS    RefSeq.
SOURCE      Stomoxys calcitrans (stable fly)
  ORGANISM  Stomoxys calcitrans
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Muscoidea; Muscidae; Stomoxys.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_081555) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_963082655.1-RS_2023_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/29/2023
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Stomoxys calcitrans"
                     /db_xref="taxon:35570"
                     /chromosome="4"
     Protein         1..434
                     /product="E3 ubiquitin-protein ligase HECW2 isoform X2"
                     /calculated_mol_wt=50516
     Region          76..432
                     /region_name="HECTc"
                     /note="HECT domain; C-terminal catalytic domain of a
                     subclass of Ubiquitin-protein ligase (E3). It binds
                     specific ubiquitin-conjugating enzymes (E2), accepts
                     ubiquitin from E2, transfers ubiquitin to substrate lysine
                     side chains, and transfers additional...; cd00078"
                     /db_xref="CDD:238033"
     Site            order(82,113,124,185,361,396..397,400..404,424,431)
                     /site_type="active"
                     /note="catalytic cleft [active]"
                     /db_xref="CDD:238033"
     Site            order(213,216..217,219..220,223,231,233,237,239,245,250,
                     267,271)
                     /site_type="active"
                     /note="E2 interaction site [active]"
                     /db_xref="CDD:238033"
     CDS             1..434
                     /gene="LOC106084257"
                     /coded_by="XM_013247829.2:394..1698"
                     /db_xref="GeneID:106084257"
ORIGIN      
        1 mgffskaayi vwavlfeqei msyvpieers pqgspvlnsr mmqrapppfr rdfeaklrsf
       61 yrkleskgyg qgphklklqi rrthlledaf rrimsankkd lqrgrlavlw dteegldygg
      121 psreffflls relfnpyygl feysandtyt vqvsplsafv dnchdwfrfs grvlglalvh
      181 qylldafftr pfykallrlp valsdlesld sefhqslqwi rdndigtgid lgltfcvtee
      241 llgrvverel kpggkniivn eknkkeyler mikwrlergv qeqteslvrg fyevvdsrlv
      301 svfdarelel viagtaeidi ndwrlnteyr sgyhdnhqvi iwfwqviekf tneqrlrllq
      361 fvtgtssipy egfsalrgst gprrfciekw gkpnalprah tcfnrldlpp yptpellyek
      421 lllaveetnt fgie