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rho GTPase-activating protein 190 isoform X3 [Stomoxys calcitrans].


LOCUS       XP_013102690            1516 aa            linear   INV 02-SEP-2023
ACCESSION   XP_013102690
VERSION     XP_013102690.1
DBLINK      BioProject: PRJNA1009844
DBSOURCE    REFSEQ: accession XM_013247236.2
KEYWORDS    RefSeq.
SOURCE      Stomoxys calcitrans (stable fly)
  ORGANISM  Stomoxys calcitrans
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Muscoidea; Muscidae; Stomoxys.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_081555) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_963082655.1-RS_2023_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/29/2023
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1516
                     /organism="Stomoxys calcitrans"
                     /db_xref="taxon:35570"
                     /chromosome="4"
     Protein         1..1516
                     /product="rho GTPase-activating protein 190 isoform X3"
                     /calculated_mol_wt=175310
     Site            19..26
                     /site_type="other"
                     /note="G1 box"
                     /db_xref="CDD:206648"
     Site            order(21..27,130,190..191,197,222..224)
                     /site_type="other"
                     /note="GTP/Mg2+ binding site [chemical binding]"
                     /db_xref="CDD:206648"
     Site            73
                     /site_type="other"
                     /note="G2 box"
                     /db_xref="CDD:206648"
     Site            77..79
                     /site_type="other"
                     /note="Switch I region"
                     /db_xref="CDD:206648"
     Region          <148..240
                     /region_name="P-loop containing Nucleoside Triphosphate
                     Hydrolases"
                     /note="Members of the P-loop NTPase domain superfamily are
                     characterized by a conserved nucleotide phosphate-binding
                     motif, also referred to as the Walker A motif
                     (GxxxxGK[S/T], where x is any residue), and the Walker B
                     motif (hhhh[D/E], where h is a...; cl38936"
                     /db_xref="CDD:476819"
     Site            order(190..191,196..197)
                     /site_type="other"
                     /note="G4 box"
                     /db_xref="CDD:206648"
     Site            222..224
                     /site_type="other"
                     /note="G5 box"
                     /db_xref="CDD:206648"
     Region          254..333
                     /region_name="RhoGAP-FF1"
                     /note="p190-A and -B Rho GAPs FF domain; pfam16512"
                     /db_xref="CDD:465153"
     Region          556..>955
                     /region_name="pseudoGTPaseD_p190RhoGAP"
                     /note="pseudoGTPase domain found in the family of
                     p190RhoGAP; cl41781"
                     /db_xref="CDD:477764"
     Region          1317..1506
                     /region_name="RhoGAP"
                     /note="GTPase-activator protein (GAP) for Rho-like
                     GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases.
                     Small GTPases (G proteins) cluster into distinct families,
                     and all act as molecular switches, active in their
                     GTP-bound form but inactive when bound to...; cl02570"
                     /db_xref="CDD:470621"
     Site            order(1341,1379,1383,1465,1468..1469,1497)
                     /site_type="other"
                     /note="GTPase interaction site"
                     /db_xref="CDD:238090"
     Site            1341
                     /site_type="active"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:238090"
     CDS             1..1516
                     /gene="LOC106083916"
                     /coded_by="XM_013247236.2:232..4782"
                     /db_xref="GeneID:106083916"
ORIGIN      
        1 mktfnisvig lsgtekdrgq vgvgksclcn rfirpmaddy fidhisvlsq sdfsgrvvnn
       61 dhflywgdvh kstdegteyt fhiieqtefm ddstfqpfkv gkmetylkrc tttkvfsaek
      121 lmyicknqlg iekeyeqkil pdgrlaidgf ivvfdvspvp nrniekqvef vqnaitlilk
      181 nkkplvlvtt knddscdlyi reaekicqrk dykgmiqlve tsahesintd laflllaqmi
      241 dkvknrikii pyqeaarsrk ellesrseav trlirnqitd yhvlwthgsk mlaqfrewte
      301 flnifghdag qklfrrhmkk lrddymnqrl hqyldkfart leymlpdvna lstsdddiwe
      361 cakgyirnhl efdqyffecp qatwqelvdm detedearip fdvletseae tvfrnflnsv
      421 qqdkkkigwk qqfkillees gfvtpgkqls evrvlfmgre cfealsehdc qqiydihqde
      481 iiekskqnfi elllehaqff qqfknvdiit qedvrqitdi lqddsrykim drldqerrvi
      541 lfqhlgfmhc pirdhcpfyh scvdnfieei ladksagshk tlgsggsgsw ksqgsdktln
      601 llivgsehla sdllndirmc tgskgeyiye nqtyylnyri angdmeafka idvyssglic
      661 vysnlqsfet lkdnlertll cnleledkfe nlpivlvyqp qdlkenevey lrneglrlae
      721 mlhcdfidhq qshqkyvyei lnividslrv semktletfp pnqtdlrilv cmfcgdqydi
      781 enlvnplide stfckamehs vvvdvfigds kkrvefilss yhginqyrde lihgfifvys
      841 tkrrsslanl svlvsqnani plqiiaites gganaffsse lcqflitegn sladrykasf
      901 mtfsadqyvk fafyspflkn awdnkydven lhveesitld sgegtlensv klprppprhe
      961 symlsstlgt dgsgsenyem lptrslnsln eerdisldei yeesnekpkm vhqkwlddkt
     1021 dgrrninkns iwnnfggsth ayttgrrhid snlnkirpkg psqtlkqpgk lnmknfqlvs
     1081 eavakmnfgg dsylpicesg dkdskrytqf dhsqldgdee dseelaeyeq iyenedctes
     1141 dscassierk nrqqnayykq inkkppvnkk tkkkkvaipv qtprvptmfg syvsppeipl
     1201 hyqrmvtaek kkigdptiin dmiktdkspe ytmvpdapvl fgapetlney nmnakclkef
     1261 eksekrrlke entrlrklqe kekeqekklk rklkqnskgf pdtesqfekl misdkveipi
     1321 flikcieyie kegldsegiy rvpgsrahvd llfqkfeeds ntvielldip vnavatalkd
     1381 ffskrlpplf skdiikelee vagsrtvcgs kvnvevktdr scrlmalktl leklppanfa
     1441 ilkyifqhfv qvsdnsklns mdsknlaicw wptlipidft dmghfeqlrp yledivqtmi
     1501 dqypylfcge dafvmv