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alpha-actinin, sarcomeric isoform X1 [Stomoxys calcitrans].


LOCUS       XP_013102657             918 aa            linear   INV 02-SEP-2023
ACCESSION   XP_013102657
VERSION     XP_013102657.1
DBLINK      BioProject: PRJNA1009844
DBSOURCE    REFSEQ: accession XM_013247203.2
KEYWORDS    RefSeq.
SOURCE      Stomoxys calcitrans (stable fly)
  ORGANISM  Stomoxys calcitrans
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Muscoidea; Muscidae; Stomoxys.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_081555) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_963082655.1-RS_2023_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/29/2023
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..918
                     /organism="Stomoxys calcitrans"
                     /db_xref="taxon:35570"
                     /chromosome="4"
     Protein         1..918
                     /product="alpha-actinin, sarcomeric isoform X1"
                     /calculated_mol_wt=106408
     Region          32..136
                     /region_name="CH_ACTN_rpt1"
                     /note="first calponin homology (CH) domain found in the
                     alpha-actinin family; cd21214"
                     /db_xref="CDD:409063"
     Site            order(37,41,85,89..91,94..95,110..118,126,128..129,
                     132..133,135..136)
                     /site_type="other"
                     /note="actin binding site [polypeptide binding]"
                     /db_xref="CDD:409063"
     Site            order(52,54,78..80)
                     /site_type="other"
                     /note="homodimer interface [polypeptide binding]"
                     /db_xref="CDD:409063"
     Region          140..253
                     /region_name="CH_ACTN_rpt2"
                     /note="second calponin homology (CH) domain found in the
                     alpha-actinin family; cd21216"
                     /db_xref="CDD:409065"
     Site            order(150,154,201..203,206..207,222..230,241,243..244,
                     247..248,250..251)
                     /site_type="other"
                     /note="putative actin binding site [polypeptide binding]"
                     /db_xref="CDD:409065"
     Region          303..526
                     /region_name="SPEC"
                     /note="Spectrin repeats, found in several proteins
                     involved in cytoskeletal structure; family members include
                     spectrin, alpha-actinin and dystrophin; the spectrin
                     repeat forms a three helix bundle with the second helix
                     interrupted by proline in some sequences; cd00176"
                     /db_xref="CDD:238103"
     Region          421..648
                     /region_name="SPEC"
                     /note="Spectrin repeats, found in several proteins
                     involved in cytoskeletal structure; family members include
                     spectrin, alpha-actinin and dystrophin; the spectrin
                     repeat forms a three helix bundle with the second helix
                     interrupted by proline in some sequences; cd00176"
                     /db_xref="CDD:238103"
     Site            421..426
                     /site_type="active"
                     /note="linker region [active]"
                     /db_xref="CDD:238103"
     Site            526..531
                     /site_type="active"
                     /note="linker region [active]"
                     /db_xref="CDD:238103"
     Region          539..761
                     /region_name="SPEC"
                     /note="Spectrin repeats, found in several proteins
                     involved in cytoskeletal structure; family members include
                     spectrin, alpha-actinin and dystrophin; the spectrin
                     repeat forms a three helix bundle with the second helix
                     interrupted by proline in some sequences; cd00176"
                     /db_xref="CDD:238103"
     Site            647..652
                     /site_type="active"
                     /note="linker region [active]"
                     /db_xref="CDD:238103"
     Region          769..>875
                     /region_name="PTZ00184"
                     /note="calmodulin; Provisional"
                     /db_xref="CDD:185504"
     Region          848..914
                     /region_name="EFhand_Ca_insen"
                     /note="Ca2+ insensitive EF hand; pfam08726"
                     /db_xref="CDD:430177"
     CDS             1..918
                     /gene="LOC106083904"
                     /coded_by="XM_013247203.2:161..2917"
                     /db_xref="GeneID:106083904"
ORIGIN      
        1 mmmenglsme dygdnymeqe eewereglld pawekqqkkt ftawcnshlr kagtgienie
       61 ddfrnglklm lllevisget lpkpdrgkmr fhkianvnka ldfiaskgvq lvsigaeeiv
      121 dgnlkmtlgm iwtiilrfai qdisveemta keglllwcqr ktapyknvnv qnfhlsfkdg
      181 lafcalihrh rpdlidyskl skdnplenln tafdvaekyl diprmldpdd lintpkpder
      241 aimtyvscyy hafqgaqqvg nmthvpeptr qytyvpnnyn aetaanrick vlkvnqener
      301 lmeeyerlas dllewirrtm pwlnsrqadn slagvqkkle eyrtyrrkhk pprveqkakl
      361 etnfntlqtk lrlsnrpayl ptegktvadi snawkglels ekafeewlla etmrlerleh
      421 laqkfkikad aheewtrgke emlqsqdfrq cklnelkalk kkheafesdl aahqdrveqi
      481 aaiaqelnsl eyhdcvsvna rcqricdqwd rlgaltqrrr taldeaeril ekidilhlef
      541 akraapfnnw ldgtredlvd mfivhtmeei qgliqahdqf katlgeadke fnlvvnlvre
      601 vesivkqyqi pgglenpytn vtahdmtrkw sdvrqlvpqr dqtlanelrk qqnnemlrrq
      661 faekanvvgp wierqmdavt aigmglqgsl edqlhrlkey eqavyaykpn ieelekihqa
      721 vqesmifenr ytnytmetlr vgweqlltsi nrninevenq iltrdskgis qdqlnefrss
      781 fnhfdkkrag rltpeefksc lvslgysigk drqgemdfqr ilavvdpnst gyvhfdafld
      841 fmtrestdtd taeqvidsfr ilagdkpyil pdelrrelpp dqaeyciqrm ppykgpngip
      901 galdymsfst alygetdl