MULTISPECIES: oxacillin-hydrolyzing class D beta-lactamase OXA-50

LOCUS       WP_003099707             262 aa            linear   BCT 20-NOV-2023
            [Pseudomonas].
ACCESSION   WP_003099707
VERSION     WP_003099707.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 262)
  AUTHORS   Zincke,D., Balasubramanian,D., Silver,L.L. and Mathee,K.
  TITLE     Characterization of a Carbapenem-Hydrolyzing Enzyme, PoxB, in
            Pseudomonas aeruginosa PAO1
  JOURNAL   Antimicrob Agents Chemother 60 (2), 936-945 (2015)
   PUBMED   26621621
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 262)
  AUTHORS   Girlich,D., Naas,T. and Nordmann,P.
  TITLE     Biochemical characterization of the naturally occurring
            oxacillinase OXA-50 of Pseudomonas aeruginosa
  JOURNAL   Antimicrob Agents Chemother 48 (6), 2043-2048 (2004)
   PUBMED   15155197
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Antimicrobial Resistance Allele
            Evidence Accession :: NG_049777.1
            Evidence Source    :: Bacterial Antimicrobial Resistance Reference
                                  Gene Database
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..262
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..262
                     /gene="blaOXA"
     Protein         1..262
                     /product="oxacillin-hydrolyzing class D beta-lactamase
                     OXA-50"
                     /EC_number="3.5.2.6"
                     /GO_function="GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /GO_function="GO:0008800 - beta-lactamase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]"
                     /calculated_mol_wt=28942
     Region          14..262
                     /region_name="YbxI"
                     /note="Beta-lactamase class D [Defense mechanisms];
                     COG2602"
                     /db_xref="CDD:442014"
ORIGIN      
        1 mrpllfsall llsghtqase wndsqavdkl fgaagvkgtf vlydvqrqry vghdreraet
       61 rfvpastykv ansliglstg avrsadevlp yggkpqrfka wehdmslrda ikasnvpvyq
      121 elarrigler mranvsrlgy gnaeigqvvd nfwlvgplki sameqtrfll rlaqgelpfp
      181 apvqstvram tllesgpgwe lhgktgwcfd ctpelgwwvg wvkrnerlyg falnidmpgg
      241 eadigkrvel gkaslkalgi lp