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melibiose:sodium symporter [Shigella flexneri 2a str. 301].


LOCUS       NP_709821                469 aa            linear   CON 24-AUG-2016
ACCESSION   NP_709821
VERSION     NP_709821.2
DBLINK      BioProject: PRJNA62907
            Assembly: GCF_000006925.2
DBSOURCE    REFSEQ: accession NC_004337.2
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri 2a str. 301
  ORGANISM  Shigella flexneri 2a str. 301
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
REFERENCE   1  (residues 1 to 469)
  AUTHORS   Jin,Q., Yuan,Z., Xu,J., Wang,Y., Shen,Y., Lu,W., Wang,J., Liu,H.,
            Yang,J., Yang,F., Zhang,X., Zhang,J., Yang,G., Wu,H., Qu,D.,
            Dong,J., Sun,L., Xue,Y., Zhao,A., Gao,Y., Zhu,J., Kan,B., Ding,K.,
            Chen,S., Cheng,H., Yao,Z., He,B., Chen,R., Ma,D., Qiang,B., Wen,Y.,
            Hou,Y. and Yu,J.
  TITLE     Genome sequence of Shigella flexneri 2a: insights into
            pathogenicity through comparison with genomes of Escherichia coli
            K12 and O157
  JOURNAL   Nucleic Acids Res. 30 (20), 4432-4441 (2002)
   PUBMED   12384590
REFERENCE   2  (residues 1 to 469)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-AUG-2011) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 469)
  AUTHORS   Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B.,
            Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y.,
            Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y.,
            Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-AUG-2011) State Key Laboratory for Moleclular
            Virology and Genetic Engineering, Microbial Genome Center of
            Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA,
            Beijing 100176, P.R.China
  REMARK    Sequence update by submitter
REFERENCE   4  (residues 1 to 469)
  AUTHORS   Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B.,
            Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y.,
            Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y.,
            Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2004) State Key Laboratory for Moleclular
            Virology and Genetic Engineering, Microbial Genome Center of
            Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA,
            Beijing 100176, P.R.China
  REMARK    Sequence update by submitter
REFERENCE   5  (residues 1 to 469)
  AUTHORS   Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B.,
            Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y.,
            Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y.,
            Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-MAY-2001) State Key Laboratory for Moleclular
            Virology and Genetic Engineering, Microbial Genome Center of
            Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA,
            Beijing 100176, P.R.China
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence is identical to AAN45528.
            
            On Dec 9, 2004 this sequence version replaced NP_709821.1.
            RefSeq Category: Reference Genome
                        CLI: Clinical Isolate
                        FGS: First Genome sequenced
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Shigella flexneri 2a str. 301"
                     /strain="301"
                     /serotype="2a"
                     /db_xref="taxon:198214"
     Protein         1..469
                     /product="melibiose:sodium symporter"
                     /calculated_mol_wt=52065
     Region          1..469
                     /region_name="PRK10429"
                     /note="melibiose:sodium transporter MelB"
                     /db_xref="CDD:182453"
     Site            order(14..15,18..19,22,55,116..117,119..121,124,145,
                     148..149,152,236,239..240,243..245,248,276,280,333..334,
                     338,342,365,368..369,372..373,376)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340890"
     CDS             1..469
                     /gene="melB"
                     /locus_tag="SF4103"
                     /coded_by="complement(NC_004337.2:4263766..4265175)"
                     /note="Code: G; COG: COG2211"
                     /transl_table=11
                     /db_xref="GeneID:1025676"
CONTIG      join(WP_005106176.1:1..469)
ORIGIN      
        1 mttklsygfg afgkdfaigi vymylmyyyt dvvglsvglv gtlflvariw daindpimgw
       61 ivnatrsrwg kfkpwiligt lansvilfll fsahlfegtt qivfvcvtyi lwgmtytimd
      121 ipfwslvpti tldkrereql vpyprffasl agfvtagvtl pfvnyvgggd rgfgfqmftl
      181 vliaffivst iitlrnvhev fssdnqssae gshltlkaiv aliykndqls cllgmalayn
      241 vasniitgfa iyyfsyvigd adlfpyylsy agaanlvtlv ffprlvksls rrilwagasi
      301 lpvlscgvll lmalmsyhnv vliviagill nvgtalfwvl qvimvadtvd ygeyklhvrc
      361 esiaysvqtm vvkggsafaa ffiavvlgmi gyvpnveqst qallgmqfim ialptlffmv
      421 tlilyfrfyr lngdtlrriq ihlldkyrkv ppepvhadip vgavsdvka