Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]
LOCUS NP_709791 354 aa linear CON 24-AUG-2016 ACCESSION NP_709791 VERSION NP_709791.1 DBLINK BioProject: PRJNA62907 Assembly: GCF_000006925.2 DBSOURCE REFSEQ: accession NC_004337.2 KEYWORDS RefSeq. SOURCE Shigella flexneri 2a str. 301 ORGANISM Shigella flexneri 2a str. 301 Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella. REFERENCE 1 (residues 1 to 354) AUTHORS Jin,Q., Yuan,Z., Xu,J., Wang,Y., Shen,Y., Lu,W., Wang,J., Liu,H., Yang,J., Yang,F., Zhang,X., Zhang,J., Yang,G., Wu,H., Qu,D., Dong,J., Sun,L., Xue,Y., Zhao,A., Gao,Y., Zhu,J., Kan,B., Ding,K., Chen,S., Cheng,H., Yao,Z., He,B., Chen,R., Ma,D., Qiang,B., Wen,Y., Hou,Y. and Yu,J. TITLE Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157 JOURNAL Nucleic Acids Res. 30 (20), 4432-4441 (2002) PUBMED 12384590 REFERENCE 2 (residues 1 to 354) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (26-AUG-2011) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 3 (residues 1 to 354) AUTHORS Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B., Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y., Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y., Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D. TITLE Direct Submission JOURNAL Submitted (03-AUG-2011) State Key Laboratory for Moleclular Virology and Genetic Engineering, Microbial Genome Center of Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA, Beijing 100176, P.R.China REMARK Sequence update by submitter REFERENCE 4 (residues 1 to 354) AUTHORS Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B., Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y., Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y., Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D. TITLE Direct Submission JOURNAL Submitted (06-DEC-2004) State Key Laboratory for Moleclular Virology and Genetic Engineering, Microbial Genome Center of Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA, Beijing 100176, P.R.China REMARK Sequence update by submitter REFERENCE 5 (residues 1 to 354) AUTHORS Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B., Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y., Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y., Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D. TITLE Direct Submission JOURNAL Submitted (21-MAY-2001) State Key Laboratory for Moleclular Virology and Genetic Engineering, Microbial Genome Center of Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA, Beijing 100176, P.R.China COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence is identical to AAN45498. RefSeq Category: Reference Genome CLI: Clinical Isolate FGS: First Genome sequenced Method: conceptual translation. FEATURES Location/Qualifiers source 1..354 /organism="Shigella flexneri 2a str. 301" /strain="301" /serotype="2a" /db_xref="taxon:198214" Protein 1..354 /product="uroporphyrinogen decarboxylase" /calculated_mol_wt=39098 Region 10..347 /region_name="URO-D" /note="Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; cd00717" /db_xref="CDD:238368" Site order(26..31,36,40,46,73..79,91,96,144,154,160,207, 209..210,248,327) /site_type="other" /note="substrate binding site [chemical binding]" /db_xref="CDD:238368" Site order(27,31,77,154,209,327) /site_type="active" /db_xref="CDD:238368" CDS 1..354 /gene="hemE" /locus_tag="SF4069" /coded_by="NC_004337.2:4216550..4217614" /note="Code: H; COG: COG0407" /transl_table=11 /db_xref="GeneID:1027590" CONTIG join(WP_000137636.1:1..354) ORIGIN 1 mtelkndryl rallrqpvdv tpvwmmrqag rylpeykatr aqagdfmslc knaelacevt 61 lqplrrypld aailfsdilt vpdamglgly feagegprft spvtckadvd klpipdpede 121 lgyvmnavrt irhelkgevp ligfsgspwt latymveggs skaftvikkm myadpqalha 181 lldklaksvt lylnaqikag aqavmifdtw ggvltgrdyq qfslyymhki vdgllrendg 241 rrvpvtlftk gggqwleama etgcdalgld wttdiadarr rvgnkvalqg nmdpsmlyap 301 parieeevat ilagfghgeg hvfnlghgih qdvppehagv fveavhrlse qyhr