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LOCUS NP_709033 312 aa linear CON 24-AUG-2016 ACCESSION NP_709033 VERSION NP_709033.2 DBLINK BioProject: PRJNA62907 Assembly: GCF_000006925.2 DBSOURCE REFSEQ: accession NC_004337.2 KEYWORDS RefSeq. SOURCE Shigella flexneri 2a str. 301 ORGANISM Shigella flexneri 2a str. 301 Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella. REFERENCE 1 (residues 1 to 312) AUTHORS Jin,Q., Yuan,Z., Xu,J., Wang,Y., Shen,Y., Lu,W., Wang,J., Liu,H., Yang,J., Yang,F., Zhang,X., Zhang,J., Yang,G., Wu,H., Qu,D., Dong,J., Sun,L., Xue,Y., Zhao,A., Gao,Y., Zhu,J., Kan,B., Ding,K., Chen,S., Cheng,H., Yao,Z., He,B., Chen,R., Ma,D., Qiang,B., Wen,Y., Hou,Y. and Yu,J. TITLE Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157 JOURNAL Nucleic Acids Res. 30 (20), 4432-4441 (2002) PUBMED 12384590 REFERENCE 2 (residues 1 to 312) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (26-AUG-2011) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 3 (residues 1 to 312) AUTHORS Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B., Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y., Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y., Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D. TITLE Direct Submission JOURNAL Submitted (03-AUG-2011) State Key Laboratory for Moleclular Virology and Genetic Engineering, Microbial Genome Center of Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA, Beijing 100176, P.R.China REMARK Sequence update by submitter REFERENCE 4 (residues 1 to 312) AUTHORS Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B., Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y., Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y., Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D. TITLE Direct Submission JOURNAL Submitted (06-DEC-2004) State Key Laboratory for Moleclular Virology and Genetic Engineering, Microbial Genome Center of Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA, Beijing 100176, P.R.China REMARK Sequence update by submitter REFERENCE 5 (residues 1 to 312) AUTHORS Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B., Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y., Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y., Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D. TITLE Direct Submission JOURNAL Submitted (21-MAY-2001) State Key Laboratory for Moleclular Virology and Genetic Engineering, Microbial Genome Center of Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA, Beijing 100176, P.R.China COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence is identical to AAN44740. On Dec 9, 2004 this sequence version replaced NP_709033.1. RefSeq Category: Reference Genome CLI: Clinical Isolate FGS: First Genome sequenced Method: conceptual translation. FEATURES Location/Qualifiers source 1..312 /organism="Shigella flexneri 2a str. 301" /strain="301" /serotype="2a" /db_xref="taxon:198214" Protein 1..312 /product="malate dehydrogenase" /calculated_mol_wt=32218 Region 1..310 /region_name="MDH_glyoxysomal_mitochondrial" /note="Glyoxysomal and mitochondrial malate dehydrogenases; cd01337" /db_xref="CDD:133422" Site order(9..12,34,76,78..79,90,94,97,117,119,146,149,177,223, 227) /site_type="other" /note="NAD binding site [chemical binding]" /db_xref="CDD:133422" Site order(14,44..45,47..49,152..153,156,209,212,216..217, 223..226,229) /site_type="other" /note="dimerization interface [polypeptide binding]" /db_xref="CDD:133422" Site order(81,87,119,153,177,210) /site_type="other" /note="Substrate binding site [chemical binding]" /db_xref="CDD:133422" CDS 1..312 /gene="mdh" /locus_tag="SF3276" /coded_by="complement(NC_004337.2:3371181..3372119)" /note="Code: C; COG: COG0039" /transl_table=11 /db_xref="GeneID:1025382" CONTIG join(WP_005050705.1:1..312) ORIGIN 1 mkvavlgaag gigqalalll ktqlpsgsel slydiapvtp gvavdlship tavkikgfsg 61 edatpalega dvvlisagva rkpgmdrsdl fnvnagivkn lvqqvakncp kacigiitnp 121 vnttvaiaae vlkkagvydk nklfgvttld iirsntfvae lkgkqpgeve vpvigghsgv 181 tilpllsqvp gvsfteqeva dltkriqnag tevveakagg gsatlsmgqa aarfglslvr 241 alqgeqgvve cayvegdgqy arffsqplll gkngveerks igtlsafeqn alegmldtlk 301 kdialgkefv nk