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octaprenyl diphosphate synthase [Shigella flexneri 2a str. 301].


LOCUS       NP_708986                323 aa            linear   CON 24-AUG-2016
ACCESSION   NP_708986
VERSION     NP_708986.1
DBLINK      BioProject: PRJNA62907
            Assembly: GCF_000006925.2
DBSOURCE    REFSEQ: accession NC_004337.2
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri 2a str. 301
  ORGANISM  Shigella flexneri 2a str. 301
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
REFERENCE   1  (residues 1 to 323)
  AUTHORS   Jin,Q., Yuan,Z., Xu,J., Wang,Y., Shen,Y., Lu,W., Wang,J., Liu,H.,
            Yang,J., Yang,F., Zhang,X., Zhang,J., Yang,G., Wu,H., Qu,D.,
            Dong,J., Sun,L., Xue,Y., Zhao,A., Gao,Y., Zhu,J., Kan,B., Ding,K.,
            Chen,S., Cheng,H., Yao,Z., He,B., Chen,R., Ma,D., Qiang,B., Wen,Y.,
            Hou,Y. and Yu,J.
  TITLE     Genome sequence of Shigella flexneri 2a: insights into
            pathogenicity through comparison with genomes of Escherichia coli
            K12 and O157
  JOURNAL   Nucleic Acids Res. 30 (20), 4432-4441 (2002)
   PUBMED   12384590
REFERENCE   2  (residues 1 to 323)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-AUG-2011) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 323)
  AUTHORS   Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B.,
            Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y.,
            Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y.,
            Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-AUG-2011) State Key Laboratory for Moleclular
            Virology and Genetic Engineering, Microbial Genome Center of
            Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA,
            Beijing 100176, P.R.China
  REMARK    Sequence update by submitter
REFERENCE   4  (residues 1 to 323)
  AUTHORS   Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B.,
            Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y.,
            Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y.,
            Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2004) State Key Laboratory for Moleclular
            Virology and Genetic Engineering, Microbial Genome Center of
            Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA,
            Beijing 100176, P.R.China
  REMARK    Sequence update by submitter
REFERENCE   5  (residues 1 to 323)
  AUTHORS   Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B.,
            Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y.,
            Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y.,
            Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-MAY-2001) State Key Laboratory for Moleclular
            Virology and Genetic Engineering, Microbial Genome Center of
            Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA,
            Beijing 100176, P.R.China
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence is identical to AAN44693.
            RefSeq Category: Reference Genome
                        CLI: Clinical Isolate
                        FGS: First Genome sequenced
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Shigella flexneri 2a str. 301"
                     /strain="301"
                     /serotype="2a"
                     /db_xref="taxon:198214"
     Protein         1..323
                     /product="octaprenyl diphosphate synthase"
                     /calculated_mol_wt=35086
     Region          1..323
                     /region_name="PRK10888"
                     /note="octaprenyl diphosphate synthase; Provisional"
                     /db_xref="CDD:182813"
     Site            order(76,79..81,83..85,87..88,93..94,146,149,170..171,174,
                     211..212,215,225,230,235)
                     /site_type="other"
                     /note="substrate binding pocket [chemical binding]"
                     /db_xref="CDD:173833"
     Site            79..88
                     /site_type="active"
                     /note="chain length determination region [active]"
                     /db_xref="CDD:173833"
     Site            order(84..85,88,93..94,149,170,211..212,215,225,230,235)
                     /site_type="active"
                     /note="substrate-Mg2+ binding site [active]"
                     /db_xref="CDD:173833"
     Site            order(84..85,88,93..94,170,211..212)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:173833"
     Site            order(84..85,88,93..94,149,170)
                     /site_type="other"
                     /note="aspartate-rich region 1"
                     /db_xref="CDD:173833"
     Site            order(90..104,218..219,225..230,233..237)
                     /site_type="active"
                     /note="active site lid residues [active]"
                     /db_xref="CDD:173833"
     Site            order(211..212,215,225,230,235)
                     /site_type="other"
                     /note="aspartate-rich region 2"
                     /db_xref="CDD:173833"
     CDS             1..323
                     /gene="ispB"
                     /locus_tag="SF3227"
                     /coded_by="NC_004337.2:3325891..3326862"
                     /note="Code: H; COG: COG0142"
                     /transl_table=11
                     /db_xref="GeneID:1024423"
CONTIG      join(WP_001047336.1:1..323)
ORIGIN      
        1 mnlekinelt aqdmagvnaa ileqlnsdvq linqlgyyiv sgggkrirpm iavlaaravg
       61 yegnahvtia aliefihtat llhddvvdes dmrrgkatan aafgnaasvl vgdfiytraf
      121 qmmtslgslk vlevmseavn viaegevlql mnvndpdite enymrviysk tarlfeaaaq
      181 csgilagctp eeekglqdyg rylgtafqli ddlldynadg eqlgknvgdd lnegkptlpl
      241 lhamhhgtpe qaqmirtaie qgngrhllep vleamnacgs lewtrqraee eadkaiaalq
      301 vlpdtpwrea liglahiavq rdr