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cystathionine beta-lyase [Shigella flexneri 2a str. 301].


LOCUS       NP_708824                395 aa            linear   CON 24-AUG-2016
ACCESSION   NP_708824
VERSION     NP_708824.1
DBLINK      BioProject: PRJNA62907
            Assembly: GCF_000006925.2
DBSOURCE    REFSEQ: accession NC_004337.2
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri 2a str. 301
  ORGANISM  Shigella flexneri 2a str. 301
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
REFERENCE   1  (residues 1 to 395)
  AUTHORS   Jin,Q., Yuan,Z., Xu,J., Wang,Y., Shen,Y., Lu,W., Wang,J., Liu,H.,
            Yang,J., Yang,F., Zhang,X., Zhang,J., Yang,G., Wu,H., Qu,D.,
            Dong,J., Sun,L., Xue,Y., Zhao,A., Gao,Y., Zhu,J., Kan,B., Ding,K.,
            Chen,S., Cheng,H., Yao,Z., He,B., Chen,R., Ma,D., Qiang,B., Wen,Y.,
            Hou,Y. and Yu,J.
  TITLE     Genome sequence of Shigella flexneri 2a: insights into
            pathogenicity through comparison with genomes of Escherichia coli
            K12 and O157
  JOURNAL   Nucleic Acids Res. 30 (20), 4432-4441 (2002)
   PUBMED   12384590
REFERENCE   2  (residues 1 to 395)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-AUG-2011) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 395)
  AUTHORS   Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B.,
            Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y.,
            Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y.,
            Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-AUG-2011) State Key Laboratory for Moleclular
            Virology and Genetic Engineering, Microbial Genome Center of
            Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA,
            Beijing 100176, P.R.China
  REMARK    Sequence update by submitter
REFERENCE   4  (residues 1 to 395)
  AUTHORS   Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B.,
            Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y.,
            Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y.,
            Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2004) State Key Laboratory for Moleclular
            Virology and Genetic Engineering, Microbial Genome Center of
            Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA,
            Beijing 100176, P.R.China
  REMARK    Sequence update by submitter
REFERENCE   5  (residues 1 to 395)
  AUTHORS   Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B.,
            Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y.,
            Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y.,
            Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-MAY-2001) State Key Laboratory for Moleclular
            Virology and Genetic Engineering, Microbial Genome Center of
            Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA,
            Beijing 100176, P.R.China
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence is identical to AAN44531.
            RefSeq Category: Reference Genome
                        CLI: Clinical Isolate
                        FGS: First Genome sequenced
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..395
                     /organism="Shigella flexneri 2a str. 301"
                     /strain="301"
                     /serotype="2a"
                     /db_xref="taxon:198214"
     Protein         1..395
                     /product="cystathionine beta-lyase"
                     /calculated_mol_wt=43086
     Region          1..395
                     /region_name="PRK08114"
                     /note="cystathionine beta-lyase; Provisional"
                     /db_xref="CDD:181231"
     Site            order(30..33,35..36,56,58,84..85,87..88,111,116,119,209,
                     217,219,235,245,247..248,329)
                     /site_type="other"
                     /note="homodimer interface [polypeptide binding]"
                     /db_xref="CDD:99738"
     Site            order(85..87,111,154,185,207,209..210,219)
                     /site_type="active"
                     /note="substrate-cofactor binding pocket [active]"
                     /db_xref="CDD:99738"
     Site            order(85..87,111,185,188,207,209..210)
                     /site_type="other"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]"
                     /db_xref="CDD:99738"
     Site            210
                     /site_type="active"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99738"
     CDS             1..395
                     /gene="metC"
                     /locus_tag="SF3053"
                     /coded_by="NC_004337.2:3147676..3148863"
                     /note="Code: E; COG: COG0626"
                     /transl_table=11
                     /db_xref="GeneID:1026637"
CONTIG      join(WP_001302355.1:1..395)
ORIGIN      
        1 madkkldtql vnagrskkyt lgavnsviqr asslvfesme akkhatrnra ngelfygrrg
       61 tlthfslqqa mceleggagc alfpcgaaav ansilafveq gdhvlmtnta yepsqdfcsk
      121 ilsklgvtts wfdpligadi vkhlqpntki vflespgsit mevhdvpaiv aavrsvvpda
      181 iimidntwaa gvlfkaldfg idvsiqaatk ylvghsdami gtavcnarcw eqlrenaylm
      241 gqmvdadtay itsrglrtlg vrlrqhhess lkvaewlaeh pqvarvnhpa lpgskghefw
      301 krdftgssgl fsfvlkkkln deelanyldn fslfsmaysw ggyeslilan qpehiaairp
      361 qgeidfsgtl irlhigledv ddliadldag fariv