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LOCUS NP_708475 375 aa linear CON 24-AUG-2016 ACCESSION NP_708475 VERSION NP_708475.1 DBLINK BioProject: PRJNA62907 Assembly: GCF_000006925.2 DBSOURCE REFSEQ: accession NC_004337.2 KEYWORDS RefSeq. SOURCE Shigella flexneri 2a str. 301 ORGANISM Shigella flexneri 2a str. 301 Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella. REFERENCE 1 (residues 1 to 375) AUTHORS Jin,Q., Yuan,Z., Xu,J., Wang,Y., Shen,Y., Lu,W., Wang,J., Liu,H., Yang,J., Yang,F., Zhang,X., Zhang,J., Yang,G., Wu,H., Qu,D., Dong,J., Sun,L., Xue,Y., Zhao,A., Gao,Y., Zhu,J., Kan,B., Ding,K., Chen,S., Cheng,H., Yao,Z., He,B., Chen,R., Ma,D., Qiang,B., Wen,Y., Hou,Y. and Yu,J. TITLE Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157 JOURNAL Nucleic Acids Res. 30 (20), 4432-4441 (2002) PUBMED 12384590 REFERENCE 2 (residues 1 to 375) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (26-AUG-2011) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 3 (residues 1 to 375) AUTHORS Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B., Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y., Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y., Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D. TITLE Direct Submission JOURNAL Submitted (03-AUG-2011) State Key Laboratory for Moleclular Virology and Genetic Engineering, Microbial Genome Center of Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA, Beijing 100176, P.R.China REMARK Sequence update by submitter REFERENCE 4 (residues 1 to 375) AUTHORS Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B., Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y., Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y., Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D. TITLE Direct Submission JOURNAL Submitted (06-DEC-2004) State Key Laboratory for Moleclular Virology and Genetic Engineering, Microbial Genome Center of Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA, Beijing 100176, P.R.China REMARK Sequence update by submitter REFERENCE 5 (residues 1 to 375) AUTHORS Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B., Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y., Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y., Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D. TITLE Direct Submission JOURNAL Submitted (21-MAY-2001) State Key Laboratory for Moleclular Virology and Genetic Engineering, Microbial Genome Center of Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA, Beijing 100176, P.R.China COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence is identical to AAN44182. RefSeq Category: Reference Genome CLI: Clinical Isolate FGS: First Genome sequenced Method: conceptual translation. FEATURES Location/Qualifiers source 1..375 /organism="Shigella flexneri 2a str. 301" /strain="301" /serotype="2a" /db_xref="taxon:198214" Protein 1..375 /product="GABA transaminase" /calculated_mol_wt=39923 Region 1..374 /region_name="AAT_I" /note="Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; cl18945" /db_xref="CDD:450240" Site order(59..61,87..88,90,155,188,190..191,217) /site_type="active" /note="inhibitor-cofactor binding pocket [active]" /db_xref="CDD:99735" Site order(60..61,87..88,155,188,191,217) /site_type="other" /note="pyridoxal 5'-phosphate binding site [chemical binding]" /db_xref="CDD:99735" Site 217 /site_type="active" /note="catalytic residue [active]" /db_xref="CDD:99735" CDS 1..375 /gene="gabT" /locus_tag="SF2689" /coded_by="NC_004337.2:2765446..2766573" /note="Code: E; COG: COG0160" /transl_table=11 /db_xref="GeneID:1023533" CONTIG join(WP_000935288.1:1..375) ORIGIN 1 mlntghlhpk vvaaveaqlk klshtcfqvl ayepylelce imnqkvpgdf akktllvttg 61 seavenavki araatkrsgt iafsgeyhgr thytlaltgk vnpysagmgl mpghvyraly 121 pcplhgised daiasihrif kndaapedia aimiepvqge ggfyaaspaf mqrlralcde 181 hgimliadev qsgagrtgtl fameqmgvap dlttfaksia ggfplagvtg raevmdavap 241 gglggtyagn piacvaalev lkvfeqenll qkandlgqkl kdgllaiaek hpeigdvrgl 301 gsmiaielfe dgdhskpdak ltaeivarar dkglillscg pyynvlrilv pltiedaqir 361 qgleiigqcf deakq