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serine hydroxymethyltransferase [Shigella flexneri 2a str. 301].


LOCUS       NP_708388                417 aa            linear   CON 24-AUG-2016
ACCESSION   NP_708388
VERSION     NP_708388.2
DBLINK      BioProject: PRJNA62907
            Assembly: GCF_000006925.2
DBSOURCE    REFSEQ: accession NC_004337.2
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri 2a str. 301
  ORGANISM  Shigella flexneri 2a str. 301
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
REFERENCE   1  (residues 1 to 417)
  AUTHORS   Jin,Q., Yuan,Z., Xu,J., Wang,Y., Shen,Y., Lu,W., Wang,J., Liu,H.,
            Yang,J., Yang,F., Zhang,X., Zhang,J., Yang,G., Wu,H., Qu,D.,
            Dong,J., Sun,L., Xue,Y., Zhao,A., Gao,Y., Zhu,J., Kan,B., Ding,K.,
            Chen,S., Cheng,H., Yao,Z., He,B., Chen,R., Ma,D., Qiang,B., Wen,Y.,
            Hou,Y. and Yu,J.
  TITLE     Genome sequence of Shigella flexneri 2a: insights into
            pathogenicity through comparison with genomes of Escherichia coli
            K12 and O157
  JOURNAL   Nucleic Acids Res. 30 (20), 4432-4441 (2002)
   PUBMED   12384590
REFERENCE   2  (residues 1 to 417)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-AUG-2011) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 417)
  AUTHORS   Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B.,
            Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y.,
            Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y.,
            Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-AUG-2011) State Key Laboratory for Moleclular
            Virology and Genetic Engineering, Microbial Genome Center of
            Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA,
            Beijing 100176, P.R.China
  REMARK    Sequence update by submitter
REFERENCE   4  (residues 1 to 417)
  AUTHORS   Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B.,
            Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y.,
            Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y.,
            Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2004) State Key Laboratory for Moleclular
            Virology and Genetic Engineering, Microbial Genome Center of
            Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA,
            Beijing 100176, P.R.China
  REMARK    Sequence update by submitter
REFERENCE   5  (residues 1 to 417)
  AUTHORS   Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B.,
            Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y.,
            Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y.,
            Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-MAY-2001) State Key Laboratory for Moleclular
            Virology and Genetic Engineering, Microbial Genome Center of
            Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA,
            Beijing 100176, P.R.China
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence is identical to AAN44095.
            
            On Dec 9, 2004 this sequence version replaced NP_708388.1.
            RefSeq Category: Reference Genome
                        CLI: Clinical Isolate
                        FGS: First Genome sequenced
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Shigella flexneri 2a str. 301"
                     /strain="301"
                     /serotype="2a"
                     /db_xref="taxon:198214"
     Protein         1..417
                     /product="serine hydroxymethyltransferase"
                     /calculated_mol_wt=45186
     Region          6..417
                     /region_name="glyA"
                     /note="serine hydroxymethyltransferase; Reviewed;
                     PRK00011"
                     /db_xref="CDD:234571"
     Site            order(12,14,21..22,31,36,54,72..73,81,96,103,138..139,265,
                     283)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:99733"
     Site            order(35,55,65,98..99,126,175,200,203,228..229,235,363)
                     /site_type="other"
                     /note="glycine-pyridoxal phosphate binding site [chemical
                     binding]"
                     /db_xref="CDD:99733"
     Site            order(35,126,229,363)
                     /site_type="active"
                     /db_xref="CDD:99733"
     Site            order(57,64,121,125,127,257,347)
                     /site_type="other"
                     /note="folate binding site [chemical binding]"
                     /db_xref="CDD:99733"
     CDS             1..417
                     /gene="glyA"
                     /locus_tag="SF2598"
                     /coded_by="complement(NC_004337.2:2669125..2670378)"
                     /note="Code: E; COG: COG0112"
                     /transl_table=11
                     /db_xref="GeneID:1025638"
CONTIG      join(WP_000919159.1:1..417)
ORIGIN      
        1 mlkremniad ydaelwqame qekvrqeehi eliasenyts prvmqaqgsq ltnkyaegyp
       61 gkryyggcey vdiveqlaid rakelfgady anvqphsgsq anfavytall epgdtvlgmn
      121 lahgghlthg spvnfsgkly nivpygidat ghidyadlek qakehkpkmi iggfsaysgv
      181 vdwakmreia dsigaylfvd mahvaglvaa gvypnpvpha hvvtttthkt lagprgglil
      241 akggseelyk klnsavfpgg qggplmhvia gkavalkeam epefktyqqq vaknakamve
      301 vflergykvv sggtdnhlfl vdlvdknltg keadaalgra nitvnknsvp ndpkspfvts
      361 girvgtpait rrgfkeaeak elagwmcdvl dsindeavie rikgkvldic arypvya