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LOCUS NP_708377 453 aa linear CON 24-AUG-2016 [Shigella flexneri 2a str. 301]. ACCESSION NP_708377 VERSION NP_708377.1 DBLINK BioProject: PRJNA62907 Assembly: GCF_000006925.2 DBSOURCE REFSEQ: accession NC_004337.2 KEYWORDS RefSeq. SOURCE Shigella flexneri 2a str. 301 ORGANISM Shigella flexneri 2a str. 301 Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella. REFERENCE 1 (residues 1 to 453) AUTHORS Jin,Q., Yuan,Z., Xu,J., Wang,Y., Shen,Y., Lu,W., Wang,J., Liu,H., Yang,J., Yang,F., Zhang,X., Zhang,J., Yang,G., Wu,H., Qu,D., Dong,J., Sun,L., Xue,Y., Zhao,A., Gao,Y., Zhu,J., Kan,B., Ding,K., Chen,S., Cheng,H., Yao,Z., He,B., Chen,R., Ma,D., Qiang,B., Wen,Y., Hou,Y. and Yu,J. TITLE Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157 JOURNAL Nucleic Acids Res. 30 (20), 4432-4441 (2002) PUBMED 12384590 REFERENCE 2 (residues 1 to 453) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (26-AUG-2011) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 3 (residues 1 to 453) AUTHORS Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B., Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y., Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y., Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D. TITLE Direct Submission JOURNAL Submitted (03-AUG-2011) State Key Laboratory for Moleclular Virology and Genetic Engineering, Microbial Genome Center of Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA, Beijing 100176, P.R.China REMARK Sequence update by submitter REFERENCE 4 (residues 1 to 453) AUTHORS Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B., Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y., Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y., Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D. TITLE Direct Submission JOURNAL Submitted (06-DEC-2004) State Key Laboratory for Moleclular Virology and Genetic Engineering, Microbial Genome Center of Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA, Beijing 100176, P.R.China REMARK Sequence update by submitter REFERENCE 5 (residues 1 to 453) AUTHORS Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B., Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y., Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y., Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D. TITLE Direct Submission JOURNAL Submitted (21-MAY-2001) State Key Laboratory for Moleclular Virology and Genetic Engineering, Microbial Genome Center of Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA, Beijing 100176, P.R.China COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence is identical to AAN44084. RefSeq Category: Reference Genome CLI: Clinical Isolate FGS: First Genome sequenced Method: conceptual translation. FEATURES Location/Qualifiers source 1..453 /organism="Shigella flexneri 2a str. 301" /strain="301" /serotype="2a" /db_xref="taxon:198214" Protein 1..453 /product="3-phenylpropionate/cinnamic acid dioxygenase subunit alpha" /calculated_mol_wt=50945 Region 18..>226 /region_name="HcaE" /note="Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit [Inorganic ion transport and metabolism, General function prediction only]; COG4638" /db_xref="CDD:443676" Region 184..433 /region_name="RHO_alpha_C_NDO-like" /note="C-terminal catalytic domain of the oxygenase alpha subunit of naphthalene 1,2-dioxygenase (NDO) and related aromatic ring hydroxylating dioxygenases; cd08881" /db_xref="CDD:176890" Site order(189..196,219..220,355,358..359,364,366,369..370, 372..373,376) /site_type="other" /note="beta subunit interface [polypeptide binding]" /db_xref="CDD:176890" Site order(205..206,210,212..213,217,373..375,377..378, 380..387,390..396,418) /site_type="other" /note="alpha subunit interface [polypeptide binding]" /db_xref="CDD:176890" Site order(206..207,210..211,213..214,218,304,306,316,361,367, 371) /site_type="active" /db_xref="CDD:176890" Site order(206..207,210..211,213..214,218,304,306,316,361,367) /site_type="other" /note="substrate binding site [chemical binding]" /db_xref="CDD:176890" Site order(213,218,371) /site_type="other" /note="Fe binding site [ion binding]" /db_xref="CDD:176890" CDS 1..453 /gene="hcaA1" /locus_tag="SF2585" /coded_by="NC_004337.2:2653884..2655245" /note="Code: PR; COG: COG2146" /transl_table=11 /db_xref="GeneID:1026946" CONTIG join(WP_000211158.1:1..453) ORIGIN 1 mttpsdlniy qlidtqngrv tpriytdpdi yqlelerifg rcwlflahes qipkpgdffn 61 tymgedavvv vrqkdgsika flnqcrhram rvsyadcgns raftcpyhgw sygingelid 121 vplepraypq glckshwgln evpcvesykg lifgnwdtsa pglhdylgdi awyldgmldr 181 reggteivgg vqkwvincnw kfpaeqfasd qyhalfshas avqvlgakdd gsdkrlgdgq 241 tarpvwetak dalqfgqdgh gsgffftekp danvwvdgav ssyyretyae aeqrlgevra 301 lrlaghnnif ptlswlngta tlrvwhprgp dqvevwafci tdkaasdevk aafensatra 361 fgpagfleqd dsenwceiqk llkghrarns klclemglgq ekrrddgipg itnyifseta 421 argmyqrwad llsseswqev ldktaayqqe vmk