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LOCUS NP_708251 831 aa linear CON 24-AUG-2016 ACCESSION NP_708251 VERSION NP_708251.1 DBLINK BioProject: PRJNA62907 Assembly: GCF_000006925.2 DBSOURCE REFSEQ: accession NC_004337.2 KEYWORDS RefSeq. SOURCE Shigella flexneri 2a str. 301 ORGANISM Shigella flexneri 2a str. 301 Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella. REFERENCE 1 (residues 1 to 831) AUTHORS Jin,Q., Yuan,Z., Xu,J., Wang,Y., Shen,Y., Lu,W., Wang,J., Liu,H., Yang,J., Yang,F., Zhang,X., Zhang,J., Yang,G., Wu,H., Qu,D., Dong,J., Sun,L., Xue,Y., Zhao,A., Gao,Y., Zhu,J., Kan,B., Ding,K., Chen,S., Cheng,H., Yao,Z., He,B., Chen,R., Ma,D., Qiang,B., Wen,Y., Hou,Y. and Yu,J. TITLE Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157 JOURNAL Nucleic Acids Res. 30 (20), 4432-4441 (2002) PUBMED 12384590 REFERENCE 2 (residues 1 to 831) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (26-AUG-2011) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 3 (residues 1 to 831) AUTHORS Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B., Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y., Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y., Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D. TITLE Direct Submission JOURNAL Submitted (03-AUG-2011) State Key Laboratory for Moleclular Virology and Genetic Engineering, Microbial Genome Center of Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA, Beijing 100176, P.R.China REMARK Sequence update by submitter REFERENCE 4 (residues 1 to 831) AUTHORS Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B., Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y., Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y., Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D. TITLE Direct Submission JOURNAL Submitted (06-DEC-2004) State Key Laboratory for Moleclular Virology and Genetic Engineering, Microbial Genome Center of Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA, Beijing 100176, P.R.China REMARK Sequence update by submitter REFERENCE 5 (residues 1 to 831) AUTHORS Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B., Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y., Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y., Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D. TITLE Direct Submission JOURNAL Submitted (21-MAY-2001) State Key Laboratory for Moleclular Virology and Genetic Engineering, Microbial Genome Center of Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA, Beijing 100176, P.R.China COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence is identical to AAN43958. RefSeq Category: Reference Genome CLI: Clinical Isolate FGS: First Genome sequenced Method: conceptual translation. FEATURES Location/Qualifiers source 1..831 /organism="Shigella flexneri 2a str. 301" /strain="301" /serotype="2a" /db_xref="taxon:198214" Protein 1..831 /product="PTS system transporter subunit IIA" /calculated_mol_wt=92042 Region 5..83 /region_name="PTS-HPr_like" /note="Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; cd00367" /db_xref="CDD:238217" Site 5..8 /site_type="other" /note="dimerization domain swap beta strand [polypeptide binding]" /db_xref="CDD:238217" Site order(14,16..17,19..20,24,27,47..50,53..54) /site_type="other" /note="regulatory protein interface [polypeptide binding]" /db_xref="CDD:238217" Site 15 /site_type="active" /db_xref="CDD:238217" Site 48 /site_type="other" /note="regulatory phosphorylation site [posttranslational modification]" /db_xref="CDD:238217" Region 117..680 /region_name="PtsA" /note="Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; COG1080" /db_xref="CDD:440698" Region 686..812 /region_name="fruA" /note="PTS system, fructose subfamily, IIA component; TIGR00848" /db_xref="CDD:273298" Site order(731,747) /site_type="active" /db_xref="CDD:238129" Site 747 /site_type="phosphorylation" /note="phosphorylation site [posttranslational modification]" /db_xref="CDD:238129" CDS 1..831 /locus_tag="SF2449" /coded_by="complement(NC_004337.2:2504830..2507325)" /note="Code: G; COG: COG1080" /transl_table=11 /db_xref="GeneID:1025242" CONTIG join(WP_000955860.1:1..831) ORIGIN 1 mltiqflcpl pnglharpaw elkeqcsqwq seitfinhrq nakadakssl aligtgtlfn 61 dscslnisgs deeqarrvle eyilvrfids dsvqptqael tahplprsls rlnpdllygn 121 vlasgvgvgt ltllqsdsld syraipasaq dstrlehsla tlaeqlnqql rerdgeskti 181 lsahlsliqd defagnirrl mteqhqglga aiisnmeqvc aklsasasdy lrervsdird 241 iseqllhitw pelkprnnlv lekptilvae dltpsqflsl dlknlagmil ektgrtshtl 301 ilarasaipv lsglpldaia ryagqpavld aqcgvlainp ndavsgyyqv aqtladkrqk 361 qqaqaaaqla ysrdnkridi vanigtalea pgafangaeg vglfrtemly mdrdsapdeq 421 eqfeayqqvl laagdkpiif rtmdiggdks ipylnipqee npflgyravr iypefaglfr 481 tqlrailraa sfgnaqlmip mvhsldqilw vkgeiqkaiv elkrdglrha etitlgimve 541 vpsvcyiidh fcdevdffsi gsndmtqyly avdrnnprvs plynpitpsf lrmlqqivtt 601 ahqrgkwvgi cgelggesry lplllglgld elsmssprip avksqlrqld seacrelarq 661 acecrsaqei ealltaftpe edvrpllale nifvdqdfsn keqaiqflcg nlgvngrteh 721 pfeleedvwq reeivttgvg fgvaiphtks qwirhssisi arlakpvdwq semgevelvi 781 mltlganegm nhvkvfsqla rklvnknfrq slfaaqdaqs iltlletelt f