histidine/lysine/arginine/ornithine ABC transporter permease HisM

LOCUS       NP_708189                238 aa            linear   CON 24-AUG-2016
            [Shigella flexneri 2a str. 301].
ACCESSION   NP_708189
VERSION     NP_708189.1
DBLINK      BioProject: PRJNA62907
            Assembly: GCF_000006925.2
DBSOURCE    REFSEQ: accession NC_004337.2
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri 2a str. 301
  ORGANISM  Shigella flexneri 2a str. 301
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
REFERENCE   1  (residues 1 to 238)
  AUTHORS   Jin,Q., Yuan,Z., Xu,J., Wang,Y., Shen,Y., Lu,W., Wang,J., Liu,H.,
            Yang,J., Yang,F., Zhang,X., Zhang,J., Yang,G., Wu,H., Qu,D.,
            Dong,J., Sun,L., Xue,Y., Zhao,A., Gao,Y., Zhu,J., Kan,B., Ding,K.,
            Chen,S., Cheng,H., Yao,Z., He,B., Chen,R., Ma,D., Qiang,B., Wen,Y.,
            Hou,Y. and Yu,J.
  TITLE     Genome sequence of Shigella flexneri 2a: insights into
            pathogenicity through comparison with genomes of Escherichia coli
            K12 and O157
  JOURNAL   Nucleic Acids Res. 30 (20), 4432-4441 (2002)
   PUBMED   12384590
REFERENCE   2  (residues 1 to 238)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-AUG-2011) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 238)
  AUTHORS   Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B.,
            Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y.,
            Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y.,
            Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-AUG-2011) State Key Laboratory for Moleclular
            Virology and Genetic Engineering, Microbial Genome Center of
            Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA,
            Beijing 100176, P.R.China
  REMARK    Sequence update by submitter
REFERENCE   4  (residues 1 to 238)
  AUTHORS   Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B.,
            Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y.,
            Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y.,
            Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2004) State Key Laboratory for Moleclular
            Virology and Genetic Engineering, Microbial Genome Center of
            Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA,
            Beijing 100176, P.R.China
  REMARK    Sequence update by submitter
REFERENCE   5  (residues 1 to 238)
  AUTHORS   Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B.,
            Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y.,
            Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y.,
            Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-MAY-2001) State Key Laboratory for Moleclular
            Virology and Genetic Engineering, Microbial Genome Center of
            Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA,
            Beijing 100176, P.R.China
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence is identical to AAN43896.
            RefSeq Category: Reference Genome
                        CLI: Clinical Isolate
                        FGS: First Genome sequenced
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..238
                     /organism="Shigella flexneri 2a str. 301"
                     /strain="301"
                     /serotype="2a"
                     /db_xref="taxon:198214"
     Protein         1..238
                     /product="histidine/lysine/arginine/ornithine ABC
                     transporter permease HisM"
                     /calculated_mol_wt=26739
     Region          1..234
                     /region_name="PRK15069"
                     /note="histidine ABC transporter permease HisM"
                     /db_xref="CDD:185029"
     Site            order(39..40,43..44,49,59..62,64..73,76..77,79,111..112,
                     114,116,119..120,122,126..127,130,147,161..162,165,
                     172..175,178..179,192..193,203..204,207..208,210..211,
                     214..215,218)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:119394"
     Site            order(65..79,172..177)
                     /site_type="active"
                     /note="conserved gate region [active]"
                     /db_xref="CDD:119394"
     Site            order(79,106,178,190,193,203)
                     /site_type="active"
                     /note="putative PBP binding loops [active]"
                     /db_xref="CDD:119394"
     Site            order(131..143,149..150,154)
                     /site_type="active"
                     /note="ABC-ATPase subunit interface [active]"
                     /db_xref="CDD:119394"
     CDS             1..238
                     /gene="hisM"
                     /locus_tag="SF2383"
                     /coded_by="complement(NC_004337.2:2432629..2433345)"
                     /note="Code: E; COG: COG0765"
                     /transl_table=11
                     /db_xref="GeneID:1025532"
CONTIG      join(WP_000569958.1:1..238)
ORIGIN      
        1 mieilheywk pllwtdgyrf tgvaitlwll ilsvviggvl alflaigrvs snkyiqfpiw
       61 lftyifrgtp lyvqllvfys gmytleivkg teflnaffrs glnctvlalt lntcayttei
      121 fagairsvph geieaarayg fstfkmyrci ilpsalrial paysnevilm lhstalafta
      181 tvpdllkiar dinaatyqpf tafgiaavly liisyvlisl frraekrwlq hvkpssth