Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]
LOCUS NP_707915 434 aa linear CON 24-AUG-2016 [Shigella flexneri 2a str. 301]. ACCESSION NP_707915 VERSION NP_707915.2 DBLINK BioProject: PRJNA62907 Assembly: GCF_000006925.2 DBSOURCE REFSEQ: accession NC_004337.2 KEYWORDS RefSeq. SOURCE Shigella flexneri 2a str. 301 ORGANISM Shigella flexneri 2a str. 301 Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella. REFERENCE 1 (residues 1 to 434) AUTHORS Jin,Q., Yuan,Z., Xu,J., Wang,Y., Shen,Y., Lu,W., Wang,J., Liu,H., Yang,J., Yang,F., Zhang,X., Zhang,J., Yang,G., Wu,H., Qu,D., Dong,J., Sun,L., Xue,Y., Zhao,A., Gao,Y., Zhu,J., Kan,B., Ding,K., Chen,S., Cheng,H., Yao,Z., He,B., Chen,R., Ma,D., Qiang,B., Wen,Y., Hou,Y. and Yu,J. TITLE Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157 JOURNAL Nucleic Acids Res. 30 (20), 4432-4441 (2002) PUBMED 12384590 REFERENCE 2 (residues 1 to 434) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (26-AUG-2011) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 3 (residues 1 to 434) AUTHORS Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B., Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y., Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y., Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D. TITLE Direct Submission JOURNAL Submitted (03-AUG-2011) State Key Laboratory for Moleclular Virology and Genetic Engineering, Microbial Genome Center of Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA, Beijing 100176, P.R.China REMARK Sequence update by submitter REFERENCE 4 (residues 1 to 434) AUTHORS Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B., Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y., Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y., Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D. TITLE Direct Submission JOURNAL Submitted (06-DEC-2004) State Key Laboratory for Moleclular Virology and Genetic Engineering, Microbial Genome Center of Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA, Beijing 100176, P.R.China REMARK Sequence update by submitter REFERENCE 5 (residues 1 to 434) AUTHORS Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B., Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y., Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y., Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D. TITLE Direct Submission JOURNAL Submitted (21-MAY-2001) State Key Laboratory for Moleclular Virology and Genetic Engineering, Microbial Genome Center of Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA, Beijing 100176, P.R.China COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence is identical to AAN43622. On Dec 9, 2004 this sequence version replaced NP_707915.1. RefSeq Category: Reference Genome CLI: Clinical Isolate FGS: First Genome sequenced Method: conceptual translation. FEATURES Location/Qualifiers source 1..434 /organism="Shigella flexneri 2a str. 301" /strain="301" /serotype="2a" /db_xref="taxon:198214" Protein 1..434 /product="bifunctional histidinal dehydrogenase/ histidinol dehydrogenase" /calculated_mol_wt=46184 Region 5..427 /region_name="hisD" /note="bifunctional histidinal dehydrogenase/ histidinol dehydrogenase; Reviewed; PRK00877" /db_xref="CDD:234853" Site order(58,130,132..133,141,162,185..186,188,209..211, 213..214,262) /site_type="other" /note="NAD binding site [chemical binding]" /db_xref="CDD:119329" Site order(83..84,87..88,90,93..94,97..98,101..102,109,111, 115..119,122,124,136..140,204,219,223,250..251,254..255, 257..259,261..262,331,336,339..340,342..350,352,354..355, 357..361,363,365,375..376,378..382,384..385,388..395, 410..411,413..419) /site_type="other" /note="dimerization interface [polypeptide binding]" /db_xref="CDD:119329" Site order(138,140,237,262,326..327,356,360..361,367,414,416, 419) /site_type="active" /note="product binding site [active]" /db_xref="CDD:119329" Site order(140,237,259,262,326..327,356,360..361,367,414,416, 419) /site_type="other" /note="substrate binding site [chemical binding]" /db_xref="CDD:119329" Site order(259,262,360,419) /site_type="other" /note="zinc binding site [ion binding]" /db_xref="CDD:119329" Site 326..327 /site_type="active" /note="catalytic residues [active]" /db_xref="CDD:119329" CDS 1..434 /gene="hisD" /locus_tag="SF2082" /coded_by="NC_004337.2:2097434..2098738" /note="Code: E; COG: COG0141" /transl_table=11 /db_xref="GeneID:1025296" CONTIG join(WP_000009597.1:1..434) ORIGIN 1 msfntiidwn sctaeqqrql lmrpaisase sitrtvndil dnvktrgdea lreysakfdk 61 ttvtalkvsa deiaaaserl sdelkqamav avksietfht aqklppvdve tqlgvrcqqv 121 trpvasvgly ipggsaplfs tvlmlatpar iagckkvvlc spppiadeil yaaqlcdvqd 181 vfnvggaqai aalafgtesv pkvdkifgpg nafvteakrq vsqrldgaai dmpagpsevl 241 viadsgatpd fvasdllsqa ehgpdsqvil ltpdadmarr vaeaverqla elpraettrq 301 alnasrlivt kdlaqcveis nqygpehlii qtrnarelvd gitsagsvfl gdwspesagd 361 yasgtnhvlp tygytatcss lgladfqkrm tvqelskegf salastietl aaaerltahk 421 navtlrvnvl keqa