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LOCUS NP_706450 285 aa linear CON 24-AUG-2016 str. 301]. ACCESSION NP_706450 VERSION NP_706450.1 DBLINK BioProject: PRJNA62907 Assembly: GCF_000006925.2 DBSOURCE REFSEQ: accession NC_004337.2 KEYWORDS RefSeq. SOURCE Shigella flexneri 2a str. 301 ORGANISM Shigella flexneri 2a str. 301 Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella. REFERENCE 1 (residues 1 to 285) AUTHORS Jin,Q., Yuan,Z., Xu,J., Wang,Y., Shen,Y., Lu,W., Wang,J., Liu,H., Yang,J., Yang,F., Zhang,X., Zhang,J., Yang,G., Wu,H., Qu,D., Dong,J., Sun,L., Xue,Y., Zhao,A., Gao,Y., Zhu,J., Kan,B., Ding,K., Chen,S., Cheng,H., Yao,Z., He,B., Chen,R., Ma,D., Qiang,B., Wen,Y., Hou,Y. and Yu,J. TITLE Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157 JOURNAL Nucleic Acids Res. 30 (20), 4432-4441 (2002) PUBMED 12384590 REFERENCE 2 (residues 1 to 285) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (26-AUG-2011) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 3 (residues 1 to 285) AUTHORS Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B., Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y., Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y., Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D. TITLE Direct Submission JOURNAL Submitted (03-AUG-2011) State Key Laboratory for Moleclular Virology and Genetic Engineering, Microbial Genome Center of Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA, Beijing 100176, P.R.China REMARK Sequence update by submitter REFERENCE 4 (residues 1 to 285) AUTHORS Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B., Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y., Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y., Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D. TITLE Direct Submission JOURNAL Submitted (06-DEC-2004) State Key Laboratory for Moleclular Virology and Genetic Engineering, Microbial Genome Center of Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA, Beijing 100176, P.R.China REMARK Sequence update by submitter REFERENCE 5 (residues 1 to 285) AUTHORS Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B., Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y., Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y., Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D. TITLE Direct Submission JOURNAL Submitted (21-MAY-2001) State Key Laboratory for Moleclular Virology and Genetic Engineering, Microbial Genome Center of Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA, Beijing 100176, P.R.China COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence is identical to AAN42157. RefSeq Category: Reference Genome CLI: Clinical Isolate FGS: First Genome sequenced Method: conceptual translation. FEATURES Location/Qualifiers source 1..285 /organism="Shigella flexneri 2a str. 301" /strain="301" /serotype="2a" /db_xref="taxon:198214" Protein 1..285 /product="2,3-dihydro-2,3-dihydroxybenzoate synthetase" /calculated_mol_wt=32423 Region 2..204 /region_name="isochorismatase" /note="Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase, catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of a vinyl ether, an uncommon reaction in biological...; cd01013" /db_xref="CDD:238495" Site order(3,42,95,126,152,155,181) /site_type="active" /note="hydrophobic substrate binding pocket [active]" /db_xref="CDD:238495" Site order(37,79,88,123,152,156) /site_type="active" /db_xref="CDD:238495" Site 151..152 /site_type="active" /note="conserved cis-peptide bond [active]" /db_xref="CDD:238495" Region 216..275 /region_name="PP-binding" /note="Phosphopantetheine attachment site; pfam00550" /db_xref="CDD:425746" CDS 1..285 /gene="entB" /locus_tag="SF0509" /coded_by="NC_004337.2:531057..531914" /note="Code: Q; COG: COG1535" /transl_table=11 /db_xref="GeneID:1027539" CONTIG join(WP_001007138.1:1..285) ORIGIN 1 maipklqaya lpeshdipqn kvdwafepqr aallihdmqd yfvsfwgenc pmmeqviani 61 aalrdyckqh nipvyytaqp keqsdedral lndmwgpglt rspeqqkvvd rltpdaddtv 121 lvkwrysafh rspleqmlke sgrnqliitg vyahigcmtt atdafmrdik pfmvadalad 181 fsrdehlmsl kyvagrsgrv vmteellpap ipaskaalre vilplldesd epfdddnlid 241 ygldsvrmma laarwrkvhg didfvmlakn ptidawwkll srevk