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LOCUS NP_706027 523 aa linear CON 24-AUG-2016 ACCESSION NP_706027 VERSION NP_706027.1 DBLINK BioProject: PRJNA62907 Assembly: GCF_000006925.2 DBSOURCE REFSEQ: accession NC_004337.2 KEYWORDS RefSeq. SOURCE Shigella flexneri 2a str. 301 ORGANISM Shigella flexneri 2a str. 301 Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella. REFERENCE 1 (residues 1 to 523) AUTHORS Jin,Q., Yuan,Z., Xu,J., Wang,Y., Shen,Y., Lu,W., Wang,J., Liu,H., Yang,J., Yang,F., Zhang,X., Zhang,J., Yang,G., Wu,H., Qu,D., Dong,J., Sun,L., Xue,Y., Zhao,A., Gao,Y., Zhu,J., Kan,B., Ding,K., Chen,S., Cheng,H., Yao,Z., He,B., Chen,R., Ma,D., Qiang,B., Wen,Y., Hou,Y. and Yu,J. TITLE Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157 JOURNAL Nucleic Acids Res. 30 (20), 4432-4441 (2002) PUBMED 12384590 REFERENCE 2 (residues 1 to 523) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (26-AUG-2011) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 3 (residues 1 to 523) AUTHORS Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B., Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y., Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y., Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D. TITLE Direct Submission JOURNAL Submitted (03-AUG-2011) State Key Laboratory for Moleclular Virology and Genetic Engineering, Microbial Genome Center of Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA, Beijing 100176, P.R.China REMARK Sequence update by submitter REFERENCE 4 (residues 1 to 523) AUTHORS Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B., Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y., Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y., Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D. TITLE Direct Submission JOURNAL Submitted (06-DEC-2004) State Key Laboratory for Moleclular Virology and Genetic Engineering, Microbial Genome Center of Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA, Beijing 100176, P.R.China REMARK Sequence update by submitter REFERENCE 5 (residues 1 to 523) AUTHORS Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B., Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y., Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y., Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D. TITLE Direct Submission JOURNAL Submitted (21-MAY-2001) State Key Laboratory for Moleclular Virology and Genetic Engineering, Microbial Genome Center of Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA, Beijing 100176, P.R.China COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence is identical to AAN41734. RefSeq Category: Reference Genome CLI: Clinical Isolate FGS: First Genome sequenced Method: conceptual translation. FEATURES Location/Qualifiers source 1..523 /organism="Shigella flexneri 2a str. 301" /strain="301" /serotype="2a" /db_xref="taxon:198214" Protein 1..523 /product="2-isopropylmalate synthase" /calculated_mol_wt=57213 Region 1..512 /region_name="PRK00915" /note="2-isopropylmalate synthase; Validated" /db_xref="CDD:234864" Site order(13..14,17,44,75,97,139,141,169,171,202,204) /site_type="active" /db_xref="CDD:163678" Site order(13..14,44) /site_type="active" /note="catalytic residues [active]" /db_xref="CDD:163678" Site order(202,204) /site_type="metal-binding" /note="metal binding site [ion binding]" /db_xref="CDD:163678" CDS 1..523 /gene="leuA" /locus_tag="SF0069" /coded_by="complement(NC_004337.2:79800..81371)" /note="Code: E; COG: COG0119" /transl_table=11 /db_xref="GeneID:1024546" CONTIG join(WP_000082848.1:1..523) ORIGIN 1 msqqviifdt tlrdgeqalq aslsvkeklq ialalermgv dvmevgfpvs spgdfesvqt 61 iarqvknsrv calarcvekd idvaaeslkv aeafrihtfi atspmhiatk lrstldevie 121 raiymvkrar nytddvefsc edagrtpiad larvveaain agattinipd tvgytmpfef 181 agiisglyer vpnidkaiis vhthddlgla vgnslaavha garqvegamn gigeragncs 241 leevimaikv rkdilnvhta inhqeiwrts qlvsqicnmp ipankaivgs gafahssgih 301 qdgvlknren yeimtpesig lnqiqlnlts rsgraavkhr mdemgykese ynldnlydaf 361 lkladkkgqv fdydlealaf igkqqeepeh frldyfsvqs gsndiataav klacgeevka 421 eaangngpvd avyqainrit dynvelvkys ltakghgkda lgqvdivtny ngrrfhgvgl 481 atdivessak amvhvlnniw raaevekelq rktqhnennk etv