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LOCUS NP_706025 466 aa linear CON 24-AUG-2016 301]. ACCESSION NP_706025 VERSION NP_706025.1 DBLINK BioProject: PRJNA62907 Assembly: GCF_000006925.2 DBSOURCE REFSEQ: accession NC_004337.2 KEYWORDS RefSeq. SOURCE Shigella flexneri 2a str. 301 ORGANISM Shigella flexneri 2a str. 301 Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella. REFERENCE 1 (residues 1 to 466) AUTHORS Jin,Q., Yuan,Z., Xu,J., Wang,Y., Shen,Y., Lu,W., Wang,J., Liu,H., Yang,J., Yang,F., Zhang,X., Zhang,J., Yang,G., Wu,H., Qu,D., Dong,J., Sun,L., Xue,Y., Zhao,A., Gao,Y., Zhu,J., Kan,B., Ding,K., Chen,S., Cheng,H., Yao,Z., He,B., Chen,R., Ma,D., Qiang,B., Wen,Y., Hou,Y. and Yu,J. TITLE Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157 JOURNAL Nucleic Acids Res. 30 (20), 4432-4441 (2002) PUBMED 12384590 REFERENCE 2 (residues 1 to 466) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (26-AUG-2011) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 3 (residues 1 to 466) AUTHORS Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B., Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y., Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y., Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D. TITLE Direct Submission JOURNAL Submitted (03-AUG-2011) State Key Laboratory for Moleclular Virology and Genetic Engineering, Microbial Genome Center of Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA, Beijing 100176, P.R.China REMARK Sequence update by submitter REFERENCE 4 (residues 1 to 466) AUTHORS Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B., Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y., Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y., Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D. TITLE Direct Submission JOURNAL Submitted (06-DEC-2004) State Key Laboratory for Moleclular Virology and Genetic Engineering, Microbial Genome Center of Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA, Beijing 100176, P.R.China REMARK Sequence update by submitter REFERENCE 5 (residues 1 to 466) AUTHORS Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B., Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y., Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y., Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D. TITLE Direct Submission JOURNAL Submitted (21-MAY-2001) State Key Laboratory for Moleclular Virology and Genetic Engineering, Microbial Genome Center of Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA, Beijing 100176, P.R.China COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence is identical to AAN41732. RefSeq Category: Reference Genome CLI: Clinical Isolate FGS: First Genome sequenced Method: conceptual translation. FEATURES Location/Qualifiers source 1..466 /organism="Shigella flexneri 2a str. 301" /strain="301" /serotype="2a" /db_xref="taxon:198214" Protein 1..466 /product="isopropylmalate isomerase large subunit" /calculated_mol_wt=49765 Region 1..466 /region_name="PRK05478" /note="3-isopropylmalate dehydratase large subunit" /db_xref="CDD:235490" Site order(33,36,128..129,411,430,435) /site_type="other" /note="substrate binding site [chemical binding]" /db_xref="CDD:153133" Site order(130,347,407,410..411,429) /site_type="other" /note="ligand binding site [chemical binding]" /db_xref="CDD:153133" CDS 1..466 /gene="leuC" /locus_tag="SF0067" /coded_by="complement(NC_004337.2:77306..78706)" /note="Code: E; COG: COG0065" /transl_table=11 /db_xref="GeneID:1024527" CONTIG join(WP_001140640.1:1..466) ORIGIN 1 maktlyeklf dahvvyeaen etpllyidrh lvhevtspqa fdglrahgrp vrqpgktfat 61 mdhnvstqtk dinacgemar iqmqeliknc kefgvelydl nhpyqgivhv mgpeqgvtlp 121 gmtivcgdsh tathgafgal afgigtseve hvlatqtlkq graktmkiev qgkaapgita 181 kdivlaiigk tgsaggtghv vefcgeaird lsmegrmtlc nmaiemgaka alvapdettf 241 nyvkgrlhap kgkdfddava ywktlqtdeg atfdtvvtlq aeeispqvtw gtnpgqvisv 301 ndnipdpasf adpverasae kalaymglkp gipltevaid kvfigsctns riedlraaae 361 iakgrkvapg vqalvvpgsg pvkaqaeaeg ldkifieagf ewrlpgcsmc lamnndrlnp 421 gercastsnr nfegrqgrgg rthlvspama aaaavtghfa dirnik