preprotein translocase subunit SecA [Listeria monocytogenes EGD-e].

LOCUS       NP_466033                837 aa            linear   CON 28-AUG-2016
ACCESSION   NP_466033
VERSION     NP_466033.1
DBLINK      BioProject: PRJNA61583
            Assembly: GCF_000196035.1
DBSOURCE    REFSEQ: accession NC_003210.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes EGD-e
  ORGANISM  Listeria monocytogenes EGD-e
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 837)
  AUTHORS   Toledo-Arana,A., Dussurget,O., Nikitas,G., Sesto,N.,
            Guet-Revillet,H., Balestrino,D., Loh,E., Gripenland,J., Tiensuu,T.,
            Vaitkevicius,K., Barthelemy,M., Vergassola,M., Nahori,M.A.,
            Soubigou,G., Regnault,B., Coppee,J.Y., Lecuit,M., Johansson,J. and
            Cossart,P.
  TITLE     The Listeria transcriptional landscape from saprophytism to
            virulence
  JOURNAL   Nature 459 (7249), 950-956 (2009)
   PUBMED   19448609
REFERENCE   2  (residues 1 to 837)
  AUTHORS   Chatterjee,S.S., Hossain,H., Otten,S., Kuenne,C., Kuchmina,K.,
            Machata,S., Domann,E., Chakraborty,T. and Hain,T.
  TITLE     Intracellular gene expression profile of Listeria monocytogenes
  JOURNAL   Infect. Immun. 74 (2), 1323-1338 (2006)
   PUBMED   16428782
REFERENCE   3  (residues 1 to 837)
  AUTHORS   Glaser,P., Frangeul,L., Buchrieser,C., Amend,A., Baquero,F.,
            Berche,P., Bloecker,H., Brandt,P., Chakraborty,T., Charbit,A.,
            Chetouani,F., Couve,E., de Daruvar,A., Dehoux,P., Domann,E.,
            Dominguez-Bernal,G., Duchaud,E., Durand,L., Dussurget,O.,
            Entian,K.-D., Fsihi,H., Garcia-Del Portillo,F., Garrido,P.,
            Gautier,L., Goebel,W., Gomez-Lopez,N., Hain,T., Hauf,J.,
            Jackson,D., Jones,L.-M., Karst,U., Kreft,J., Kuhn,M., Kunst,F.,
            Kurapkat,G., Madueno,E., Maitournam,A., Mata Vicente,J., Ng,E.,
            Nordsiek,G., Novella,S., de Pablos,B., Perez-Diaz,J.-C., Remmel,B.,
            Rose,M., Rusniok,C., Schlueter,T., Simoes,N., Tierrez,A.,
            Vazquez-Boland,J.-A., Voss,H., Wehland,J. and Cossart,P.
  TITLE     Comparative genomics of Listeria species
  JOURNAL   Science 294 (5543), 849-852 (2001)
   PUBMED   11679669
REFERENCE   4  (residues 1 to 837)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2001) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 837)
  AUTHORS   Glaser,P., Frangeul,L. and Rusniok,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-JUN-2001) Glaser P., Institut Pasteur, Genomique des
            Microorganismes Pathogenes, 25 rue du Docteur Roux, 75724 Paris
            Cedex 15, FRANCE
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from CAD00588.
            RefSeq Category: Reference Genome
                        FGS: First Genome sequenced
                        MOD: Model Organism
                        UPR: UniProt Genome
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..837
                     /organism="Listeria monocytogenes EGD-e"
                     /strain="EGD-e"
                     /db_xref="taxon:169963"
     Protein         1..837
                     /product="preprotein translocase subunit SecA"
                     /calculated_mol_wt=94528
     Region          1..837
                     /region_name="SecA"
                     /note="Preprotein translocase subunit SecA (ATPase, RNA
                     helicase) [Intracellular trafficking, secretion, and
                     vesicular transport]; COG0653"
                     /db_xref="CDD:440418"
     CDS             1..837
                     /gene="secA"
                     /locus_tag="lmo2510"
                     /gene_synonym="azi; div"
                     /coded_by="complement(NC_003210.1:2587300..2589813)"
                     /experiment="EXISTENCE:[PMID:19448609]"
                     /note="functions in protein export; can interact with
                     acidic membrane phospholipids and the SecYEG protein
                     complex; binds to preproteins; binds to ATP and undergoes
                     a conformational change to promote membrane insertion of
                     SecA/bound preprotein; ATP hydrolysis appears to drive
                     release of the preprotein from SecA and deinsertion of
                     SecA from the membrane; additional proteins SecD/F/YajC
                     aid SecA recycling; exists in an equilibrium between
                     monomers and dimers; may possibly form higher order
                     oligomers; proteins in this cluster correspond SecA1;
                     SecA2 is not essential and seems to play a role in
                     secretion of a subset of proteins"
                     /transl_table=11
                     /db_xref="GeneID:985470"
CONTIG      join(WP_003722642.1:1..837)
ORIGIN      
        1 magllkkife sgkkdvkyle rkadeiiala detaalsdda lrektvefke rvqkgetldd
       61 llveafavar egakralgly pfkvqlmggi vlhegniaem ktgegktlta tlpvylnals
      121 gegvhvvtvn eylahrdaee mgvlynflgl svglnlnals stekreayac ditystnnel
      181 gfdylrdnmv vykeemvqrp lafavidevd silvdeartp liisgeaeks tilyvrantf
      241 vrtlteeedy tvdiktksvq ltedgmtkge nyfdvenlfd lentvilhhi aqalkanytm
      301 sldvdyvvqd devlivdqft grimkgrrfs eglhqaleak egvtiqnesk tmatitfqny
      361 frmykklagm tgtakteeee frdiynmrvi eiptnkviir ddrpdliytt ieakfnavve
      421 diaerhakgq pvlvgtvaie tselissklk rkgikhdvln akqhereadi ikhagergav
      481 viatnmagrg tdiklgegti eagglavigt erhesrridn qlrgrsgrqg dpgvtqfyls
      541 medelmrrfg sdnmksmmer fgmaedaiqs kmvsravesa qrrvegnnfd srkqvlqydd
      601 vlrqqreviy kqryevinae nslreiieqm iqrtvnfivs snasshepee awnlqgiidy
      661 vdanllpegt itledlqnrt sediqnlild kikaaydeke tllppeefne fekvvllrvv
      721 dtkwvdhida mdhlrdgihl raygqidplr eyqsegfemf eamvssided varyimkaei
      781 rqnlereqva kgeainpaeg kpeakrqpir kdqhigrndp cpcgsgkkyk nchgkea