fumarate hydratase [Listeria monocytogenes EGD-e].

LOCUS       NP_465749                455 aa            linear   CON 28-AUG-2016
ACCESSION   NP_465749
VERSION     NP_465749.1
DBLINK      BioProject: PRJNA61583
            Assembly: GCF_000196035.1
DBSOURCE    REFSEQ: accession NC_003210.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes EGD-e
  ORGANISM  Listeria monocytogenes EGD-e
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 455)
  AUTHORS   Toledo-Arana,A., Dussurget,O., Nikitas,G., Sesto,N.,
            Guet-Revillet,H., Balestrino,D., Loh,E., Gripenland,J., Tiensuu,T.,
            Vaitkevicius,K., Barthelemy,M., Vergassola,M., Nahori,M.A.,
            Soubigou,G., Regnault,B., Coppee,J.Y., Lecuit,M., Johansson,J. and
            Cossart,P.
  TITLE     The Listeria transcriptional landscape from saprophytism to
            virulence
  JOURNAL   Nature 459 (7249), 950-956 (2009)
   PUBMED   19448609
REFERENCE   2  (residues 1 to 455)
  AUTHORS   Chatterjee,S.S., Hossain,H., Otten,S., Kuenne,C., Kuchmina,K.,
            Machata,S., Domann,E., Chakraborty,T. and Hain,T.
  TITLE     Intracellular gene expression profile of Listeria monocytogenes
  JOURNAL   Infect. Immun. 74 (2), 1323-1338 (2006)
   PUBMED   16428782
REFERENCE   3  (residues 1 to 455)
  AUTHORS   Glaser,P., Frangeul,L., Buchrieser,C., Amend,A., Baquero,F.,
            Berche,P., Bloecker,H., Brandt,P., Chakraborty,T., Charbit,A.,
            Chetouani,F., Couve,E., de Daruvar,A., Dehoux,P., Domann,E.,
            Dominguez-Bernal,G., Duchaud,E., Durand,L., Dussurget,O.,
            Entian,K.-D., Fsihi,H., Garcia-Del Portillo,F., Garrido,P.,
            Gautier,L., Goebel,W., Gomez-Lopez,N., Hain,T., Hauf,J.,
            Jackson,D., Jones,L.-M., Karst,U., Kreft,J., Kuhn,M., Kunst,F.,
            Kurapkat,G., Madueno,E., Maitournam,A., Mata Vicente,J., Ng,E.,
            Nordsiek,G., Novella,S., de Pablos,B., Perez-Diaz,J.-C., Remmel,B.,
            Rose,M., Rusniok,C., Schlueter,T., Simoes,N., Tierrez,A.,
            Vazquez-Boland,J.-A., Voss,H., Wehland,J. and Cossart,P.
  TITLE     Comparative genomics of Listeria species
  JOURNAL   Science 294 (5543), 849-852 (2001)
   PUBMED   11679669
REFERENCE   4  (residues 1 to 455)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2001) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 455)
  AUTHORS   Glaser,P., Frangeul,L. and Rusniok,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-JUN-2001) Glaser P., Institut Pasteur, Genomique des
            Microorganismes Pathogenes, 25 rue du Docteur Roux, 75724 Paris
            Cedex 15, FRANCE
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from CAD00303.
            RefSeq Category: Reference Genome
                        FGS: First Genome sequenced
                        MOD: Model Organism
                        UPR: UniProt Genome
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..455
                     /organism="Listeria monocytogenes EGD-e"
                     /strain="EGD-e"
                     /db_xref="taxon:169963"
     Protein         1..455
                     /product="fumarate hydratase"
                     /EC_number="4.2.1.2"
                     /calculated_mol_wt=49495
     Region          3..454
                     /region_name="fumC"
                     /note="fumarate hydratase; Reviewed; PRK00485"
                     /db_xref="CDD:234779"
     Site            order(96,98,122..125,132..134,181,317,319,324)
                     /site_type="active"
                     /db_xref="CDD:176465"
     Site            order(179..182,186,192..193,199,203,207,225,255..256,259,
                     262..263,265,268..269,272,275..276,279..280,282..283,
                     286..287,337,345,348..350,403)
                     /site_type="other"
                     /note="tetramer interface [polypeptide binding]"
                     /db_xref="CDD:176465"
     CDS             1..455
                     /gene="fumC"
                     /locus_tag="lmo2225"
                     /coded_by="complement(NC_003210.1:2314511..2315878)"
                     /experiment="EXISTENCE:[PMID:19448609]"
                     /note="class II family (does not require metal);
                     tetrameric enzyme; fumarase C; reversibly converts
                     (S)-malate to fumarate and water; functions in the TCA
                     cycle"
                     /transl_table=11
                     /db_xref="GeneID:987997"
CONTIG      join(WP_003731883.1:1..455)
ORIGIN      
        1 merierdtlg eisvdatkyw gaqterskrn faigdnpmpi eiiyafaqlk katakvnaae
       61 gklaeekaia igqvcdqiiq geldehfplv vwqtgsgtqs nmnvneviah vanltlgegq
      121 ihpnddvnms qssndtfpta mhiaaygalv tkllpeitkm eavltekknk ymhlvkigrt
      181 hlqdatpltl gqeisgweac ltnnknylet smkailplai ggtavgtgln asrdfgdkva
      241 eelmkqtgyp ftsdsnkyfa ltshspinfv hgairslasd lmkiandirl lasgprsgig
      301 eleipanepg ssimpgkvnp tqceaitmva aqvmgndvti nvaasqgnfe lnvykpviif
      361 nflesiklla dsmrsfrvhc legltanekv ietkvndslm lvtalnphig yekaakiakl
      421 afdenttlke aaiktgfvte kefdlwinpl kmtnl