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LOCUS NP_465592 542 aa linear CON 28-AUG-2016 ACCESSION NP_465592 VERSION NP_465592.1 DBLINK BioProject: PRJNA61583 Assembly: GCF_000196035.1 DBSOURCE REFSEQ: accession NC_003210.1 KEYWORDS RefSeq. SOURCE Listeria monocytogenes EGD-e ORGANISM Listeria monocytogenes EGD-e Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae; Listeria. REFERENCE 1 (residues 1 to 542) AUTHORS Toledo-Arana,A., Dussurget,O., Nikitas,G., Sesto,N., Guet-Revillet,H., Balestrino,D., Loh,E., Gripenland,J., Tiensuu,T., Vaitkevicius,K., Barthelemy,M., Vergassola,M., Nahori,M.A., Soubigou,G., Regnault,B., Coppee,J.Y., Lecuit,M., Johansson,J. and Cossart,P. TITLE The Listeria transcriptional landscape from saprophytism to virulence JOURNAL Nature 459 (7249), 950-956 (2009) PUBMED 19448609 REFERENCE 2 (residues 1 to 542) AUTHORS Chatterjee,S.S., Hossain,H., Otten,S., Kuenne,C., Kuchmina,K., Machata,S., Domann,E., Chakraborty,T. and Hain,T. TITLE Intracellular gene expression profile of Listeria monocytogenes JOURNAL Infect. Immun. 74 (2), 1323-1338 (2006) PUBMED 16428782 REFERENCE 3 (residues 1 to 542) AUTHORS Glaser,P., Frangeul,L., Buchrieser,C., Amend,A., Baquero,F., Berche,P., Bloecker,H., Brandt,P., Chakraborty,T., Charbit,A., Chetouani,F., Couve,E., de Daruvar,A., Dehoux,P., Domann,E., Dominguez-Bernal,G., Duchaud,E., Durand,L., Dussurget,O., Entian,K.-D., Fsihi,H., Garcia-Del Portillo,F., Garrido,P., Gautier,L., Goebel,W., Gomez-Lopez,N., Hain,T., Hauf,J., Jackson,D., Jones,L.-M., Karst,U., Kreft,J., Kuhn,M., Kunst,F., Kurapkat,G., Madueno,E., Maitournam,A., Mata Vicente,J., Ng,E., Nordsiek,G., Novella,S., de Pablos,B., Perez-Diaz,J.-C., Remmel,B., Rose,M., Rusniok,C., Schlueter,T., Simoes,N., Tierrez,A., Vazquez-Boland,J.-A., Voss,H., Wehland,J. and Cossart,P. TITLE Comparative genomics of Listeria species JOURNAL Science 294 (5543), 849-852 (2001) PUBMED 11679669 REFERENCE 4 (residues 1 to 542) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (08-NOV-2001) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 5 (residues 1 to 542) AUTHORS Glaser,P., Frangeul,L. and Rusniok,C. TITLE Direct Submission JOURNAL Submitted (06-JUN-2001) Glaser P., Institut Pasteur, Genomique des Microorganismes Pathogenes, 25 rue du Docteur Roux, 75724 Paris Cedex 15, FRANCE COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CAD00146. RefSeq Category: Reference Genome FGS: First Genome sequenced MOD: Model Organism UPR: UniProt Genome Method: conceptual translation. FEATURES Location/Qualifiers source 1..542 /organism="Listeria monocytogenes EGD-e" /strain="EGD-e" /db_xref="taxon:169963" Protein 1..542 /product="molecular chaperone GroEL" /calculated_mol_wt=57237 Region 1..531 /region_name="groEL" /note="chaperonin GroEL; Reviewed; PRK00013" /db_xref="CDD:234573" Site order(3,7,24,35..38,40,45..46,48,58,60,68,72,75,195,227, 255,382,384,456,510,513..519) /site_type="other" /note="ring oligomerisation interface [polypeptide binding]" /db_xref="CDD:239460" Site order(30..32,86,90,149,396,413,451,490,492) /site_type="other" /note="ATP/Mg binding site [chemical binding]" /db_xref="CDD:239460" Site order(108,431,449,458,460..461,464) /site_type="active" /note="stacking interactions [active]" /db_xref="CDD:239460" Site order(140,184,191,373,407..408) /site_type="other" /note="hinge regions" /db_xref="CDD:239460" CDS 1..542 /gene="groEL" /locus_tag="lmo2068" /coded_by="complement(NC_003210.1:2147684..2149312)" /experiment="EXISTENCE:[PMID:19448609]" /note="60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth" /transl_table=11 /db_xref="GeneID:987925" CONTIG join(WP_003726503.1:1..542) ORIGIN 1 makdikfsed arramlrgvd qlanavkvtl gpkgrnvvle kkfgsplitn dgvtiakeie 61 ledpfenmga klvsevaskt ndvagdgttt atvlaqamiq eglknvtaga npvgvrrgie 121 kavataieel kaiskpiesk esiaqvaais sgdeevgkli aeamervgnd gvitieeskg 181 fateldvveg mqfdrgytsp ymvtdsdkme avlekpyili tdkkinniqe ilpvleqvvq 241 qgrpmliiae dvegeaqatl vlnklrgtfn vvavkapgfg drrkamledi ailtggqvit 301 edlglelkta tvdqlgtank vvvtkddtti vegagdstqi sarvnqiraq meettsefdr 361 eklqerlakl aggvavvkvg aatetelker klriedalns traaveegiv agggtalvsi 421 ynkvaaleae gdvetginiv lrsleepvrq iahnaglegs viverlkhea vgvgfnaang 481 ewvnmidagi vdptkvtrsa lqnassvaal lltteavvad kpdengpaav pdmgmggmgg 541 mm