UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase

LOCUS       NP_465562                491 aa            linear   CON 28-AUG-2016
            [Listeria monocytogenes EGD-e].
ACCESSION   NP_465562
VERSION     NP_465562.1
DBLINK      BioProject: PRJNA61583
            Assembly: GCF_000196035.1
DBSOURCE    REFSEQ: accession NC_003210.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes EGD-e
  ORGANISM  Listeria monocytogenes EGD-e
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 491)
  AUTHORS   Toledo-Arana,A., Dussurget,O., Nikitas,G., Sesto,N.,
            Guet-Revillet,H., Balestrino,D., Loh,E., Gripenland,J., Tiensuu,T.,
            Vaitkevicius,K., Barthelemy,M., Vergassola,M., Nahori,M.A.,
            Soubigou,G., Regnault,B., Coppee,J.Y., Lecuit,M., Johansson,J. and
            Cossart,P.
  TITLE     The Listeria transcriptional landscape from saprophytism to
            virulence
  JOURNAL   Nature 459 (7249), 950-956 (2009)
   PUBMED   19448609
REFERENCE   2  (residues 1 to 491)
  AUTHORS   Chatterjee,S.S., Hossain,H., Otten,S., Kuenne,C., Kuchmina,K.,
            Machata,S., Domann,E., Chakraborty,T. and Hain,T.
  TITLE     Intracellular gene expression profile of Listeria monocytogenes
  JOURNAL   Infect. Immun. 74 (2), 1323-1338 (2006)
   PUBMED   16428782
REFERENCE   3  (residues 1 to 491)
  AUTHORS   Glaser,P., Frangeul,L., Buchrieser,C., Amend,A., Baquero,F.,
            Berche,P., Bloecker,H., Brandt,P., Chakraborty,T., Charbit,A.,
            Chetouani,F., Couve,E., de Daruvar,A., Dehoux,P., Domann,E.,
            Dominguez-Bernal,G., Duchaud,E., Durand,L., Dussurget,O.,
            Entian,K.-D., Fsihi,H., Garcia-Del Portillo,F., Garrido,P.,
            Gautier,L., Goebel,W., Gomez-Lopez,N., Hain,T., Hauf,J.,
            Jackson,D., Jones,L.-M., Karst,U., Kreft,J., Kuhn,M., Kunst,F.,
            Kurapkat,G., Madueno,E., Maitournam,A., Mata Vicente,J., Ng,E.,
            Nordsiek,G., Novella,S., de Pablos,B., Perez-Diaz,J.-C., Remmel,B.,
            Rose,M., Rusniok,C., Schlueter,T., Simoes,N., Tierrez,A.,
            Vazquez-Boland,J.-A., Voss,H., Wehland,J. and Cossart,P.
  TITLE     Comparative genomics of Listeria species
  JOURNAL   Science 294 (5543), 849-852 (2001)
   PUBMED   11679669
REFERENCE   4  (residues 1 to 491)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2001) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 491)
  AUTHORS   Glaser,P., Frangeul,L. and Rusniok,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-JUN-2001) Glaser P., Institut Pasteur, Genomique des
            Microorganismes Pathogenes, 25 rue du Docteur Roux, 75724 Paris
            Cedex 15, FRANCE
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from CAD00116.
            RefSeq Category: Reference Genome
                        FGS: First Genome sequenced
                        MOD: Model Organism
                        UPR: UniProt Genome
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Listeria monocytogenes EGD-e"
                     /strain="EGD-e"
                     /db_xref="taxon:169963"
     Protein         1..491
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /calculated_mol_wt=53616
     Region          25..486
                     /region_name="MurE"
                     /note="UDP-N-acetylmuramyl tripeptide synthase [Cell
                     wall/membrane/envelope biogenesis]; COG0769"
                     /db_xref="CDD:440532"
     CDS             1..491
                     /gene="murE"
                     /locus_tag="lmo2038"
                     /coded_by="complement(NC_003210.1:2119833..2121308)"
                     /experiment="EXISTENCE:[PMID:19448609]"
                     /note="involved in cell wall formation; peptidoglycan
                     synthesis; cytoplasmic enzyme; catalyzes the addition of
                     meso-diaminopimelic acid to the nucleotide precursor
                     UDP-N-aceylmuramoyl-l-alanyl-d-glutamate"
                     /transl_table=11
                     /db_xref="GeneID:987940"
CONTIG      join(WP_010989880.1:1..491)
ORIGIN      
        1 mklnelmqai pvftgevset ieishiaqds rkvkpgtlfi cidgevvdgh kfasravelg
       61 avaiiaekqv dvsipviyvr dskramamla dyfygsptqa lklvgitgtn gkttvshlve
      121 qivrengeqt gligtmyrki gdqiletknt tpdsltlqet frdmllsgvs tavmevssha
      181 lvqgrvygsd ydvavfmnls qdhldyhhtm eeyanaksll faqlgnsyht snpkiavlna
      241 ddaesvrmqk ataahiitfg ikqeadfqas nikitshgst fdlgtpvgnf tlkikmignf
      301 svynvlaaia tsfalhipme kaiktvesip gvkgrfelvh agqefpvivd yahtpdglln
      361 vletidefae krvfvvvgcg gdrdkgkrpq makiavdyat npiftsdnpr senpraiied
      421 miqgvpesda yvvhenrrda irfavnqaea gdviliagkg hedyqvvgde vidfddrvea
      481 riaiekklgl a