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dihydroorotase [Listeria monocytogenes EGD-e].


LOCUS       NP_465362                426 aa            linear   CON 28-AUG-2016
ACCESSION   NP_465362
VERSION     NP_465362.1
DBLINK      BioProject: PRJNA61583
            Assembly: GCF_000196035.1
DBSOURCE    REFSEQ: accession NC_003210.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes EGD-e
  ORGANISM  Listeria monocytogenes EGD-e
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 426)
  AUTHORS   Toledo-Arana,A., Dussurget,O., Nikitas,G., Sesto,N.,
            Guet-Revillet,H., Balestrino,D., Loh,E., Gripenland,J., Tiensuu,T.,
            Vaitkevicius,K., Barthelemy,M., Vergassola,M., Nahori,M.A.,
            Soubigou,G., Regnault,B., Coppee,J.Y., Lecuit,M., Johansson,J. and
            Cossart,P.
  TITLE     The Listeria transcriptional landscape from saprophytism to
            virulence
  JOURNAL   Nature 459 (7249), 950-956 (2009)
   PUBMED   19448609
REFERENCE   2  (residues 1 to 426)
  AUTHORS   Chatterjee,S.S., Hossain,H., Otten,S., Kuenne,C., Kuchmina,K.,
            Machata,S., Domann,E., Chakraborty,T. and Hain,T.
  TITLE     Intracellular gene expression profile of Listeria monocytogenes
  JOURNAL   Infect. Immun. 74 (2), 1323-1338 (2006)
   PUBMED   16428782
REFERENCE   3  (residues 1 to 426)
  AUTHORS   Glaser,P., Frangeul,L., Buchrieser,C., Amend,A., Baquero,F.,
            Berche,P., Bloecker,H., Brandt,P., Chakraborty,T., Charbit,A.,
            Chetouani,F., Couve,E., de Daruvar,A., Dehoux,P., Domann,E.,
            Dominguez-Bernal,G., Duchaud,E., Durand,L., Dussurget,O.,
            Entian,K.-D., Fsihi,H., Garcia-Del Portillo,F., Garrido,P.,
            Gautier,L., Goebel,W., Gomez-Lopez,N., Hain,T., Hauf,J.,
            Jackson,D., Jones,L.-M., Karst,U., Kreft,J., Kuhn,M., Kunst,F.,
            Kurapkat,G., Madueno,E., Maitournam,A., Mata Vicente,J., Ng,E.,
            Nordsiek,G., Novella,S., de Pablos,B., Perez-Diaz,J.-C., Remmel,B.,
            Rose,M., Rusniok,C., Schlueter,T., Simoes,N., Tierrez,A.,
            Vazquez-Boland,J.-A., Voss,H., Wehland,J. and Cossart,P.
  TITLE     Comparative genomics of Listeria species
  JOURNAL   Science 294 (5543), 849-852 (2001)
   PUBMED   11679669
REFERENCE   4  (residues 1 to 426)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2001) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 426)
  AUTHORS   Glaser,P., Frangeul,L. and Rusniok,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-JUN-2001) Glaser P., Institut Pasteur, Genomique des
            Microorganismes Pathogenes, 25 rue du Docteur Roux, 75724 Paris
            Cedex 15, FRANCE
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from CAC99915.
            RefSeq Category: Reference Genome
                        FGS: First Genome sequenced
                        MOD: Model Organism
                        UPR: UniProt Genome
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Listeria monocytogenes EGD-e"
                     /strain="EGD-e"
                     /db_xref="taxon:169963"
     Protein         1..426
                     /product="dihydroorotase"
                     /EC_number="3.5.2.3"
                     /calculated_mol_wt=46029
     Region          1..422
                     /region_name="pyrC"
                     /note="dihydroorotase; Validated; PRK09357"
                     /db_xref="CDD:236479"
     Site            order(58,60,177,230,303)
                     /site_type="active"
                     /db_xref="CDD:238642"
     CDS             1..426
                     /gene="pyrC"
                     /locus_tag="lmo1837"
                     /coded_by="complement(NC_003210.1:1913907..1915187)"
                     /experiment="EXISTENCE:[PMID:19448609]"
                     /note="catalyzes the formation of N-carbamoyl-L-aspartate
                     from (S)-dihydroorotate in pyrimidine biosynthesis"
                     /transl_table=11
                     /db_xref="GeneID:985870"
CONTIG      join(WP_003723081.1:1..426)
ORIGIN      
        1 myvlkngqvl nasgkleskd vliqngkvnl iadsievtsg eefdatgkli tpgfidvhvh
       61 lrepggehke tiltgtkaaa rggytticsm pntkpvpdsk evmesiqaki ketakvrvlp
      121 yasittslgt delvdfealk eagafaftdd gvgvqlagtm yeamkraaal dmaivahced
      181 nsliyggvvh dgifaekegl kgipniaesv qiardvllae aagchyhvch istkesvrvv
      241 rdakragirv taevsphhli ldeeaipgnd gnwkmnpplr skedraalle glldgtidfi
      301 atdhaphaae eknvpmeqaa fgivgletaf pllythfvkt newtlkqlid wmtvkpaecf
      361 klpygkleeg svadivvldl ekeanidpdt fyskgkntpf vgetcigwpv atfaegtlvy
      421 negeik