adenylosuccinate lyase [Listeria monocytogenes EGD-e].

LOCUS       NP_465298                430 aa            linear   CON 28-AUG-2016
ACCESSION   NP_465298
VERSION     NP_465298.1
DBLINK      BioProject: PRJNA61583
            Assembly: GCF_000196035.1
DBSOURCE    REFSEQ: accession NC_003210.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes EGD-e
  ORGANISM  Listeria monocytogenes EGD-e
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 430)
  AUTHORS   Toledo-Arana,A., Dussurget,O., Nikitas,G., Sesto,N.,
            Guet-Revillet,H., Balestrino,D., Loh,E., Gripenland,J., Tiensuu,T.,
            Vaitkevicius,K., Barthelemy,M., Vergassola,M., Nahori,M.A.,
            Soubigou,G., Regnault,B., Coppee,J.Y., Lecuit,M., Johansson,J. and
            Cossart,P.
  TITLE     The Listeria transcriptional landscape from saprophytism to
            virulence
  JOURNAL   Nature 459 (7249), 950-956 (2009)
   PUBMED   19448609
REFERENCE   2  (residues 1 to 430)
  AUTHORS   Chatterjee,S.S., Hossain,H., Otten,S., Kuenne,C., Kuchmina,K.,
            Machata,S., Domann,E., Chakraborty,T. and Hain,T.
  TITLE     Intracellular gene expression profile of Listeria monocytogenes
  JOURNAL   Infect. Immun. 74 (2), 1323-1338 (2006)
   PUBMED   16428782
REFERENCE   3  (residues 1 to 430)
  AUTHORS   Glaser,P., Frangeul,L., Buchrieser,C., Amend,A., Baquero,F.,
            Berche,P., Bloecker,H., Brandt,P., Chakraborty,T., Charbit,A.,
            Chetouani,F., Couve,E., de Daruvar,A., Dehoux,P., Domann,E.,
            Dominguez-Bernal,G., Duchaud,E., Durand,L., Dussurget,O.,
            Entian,K.-D., Fsihi,H., Garcia-Del Portillo,F., Garrido,P.,
            Gautier,L., Goebel,W., Gomez-Lopez,N., Hain,T., Hauf,J.,
            Jackson,D., Jones,L.-M., Karst,U., Kreft,J., Kuhn,M., Kunst,F.,
            Kurapkat,G., Madueno,E., Maitournam,A., Mata Vicente,J., Ng,E.,
            Nordsiek,G., Novella,S., de Pablos,B., Perez-Diaz,J.-C., Remmel,B.,
            Rose,M., Rusniok,C., Schlueter,T., Simoes,N., Tierrez,A.,
            Vazquez-Boland,J.-A., Voss,H., Wehland,J. and Cossart,P.
  TITLE     Comparative genomics of Listeria species
  JOURNAL   Science 294 (5543), 849-852 (2001)
   PUBMED   11679669
REFERENCE   4  (residues 1 to 430)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2001) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 430)
  AUTHORS   Glaser,P., Frangeul,L. and Rusniok,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-JUN-2001) Glaser P., Institut Pasteur, Genomique des
            Microorganismes Pathogenes, 25 rue du Docteur Roux, 75724 Paris
            Cedex 15, FRANCE
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from CAC99851.
            RefSeq Category: Reference Genome
                        FGS: First Genome sequenced
                        MOD: Model Organism
                        UPR: UniProt Genome
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Listeria monocytogenes EGD-e"
                     /strain="EGD-e"
                     /db_xref="taxon:169963"
     Protein         1..430
                     /product="adenylosuccinate lyase"
                     /EC_number="4.3.2.2"
                     /calculated_mol_wt=48954
     Region          4..427
                     /region_name="Adenylsuccinate_lyase_1"
                     /note="Adenylsuccinate lyase (ASL)_subgroup 1; cd01360"
                     /db_xref="CDD:176464"
     Site            order(15..16,69,78,87..88,90..91,139..144,146,152..153,
                     156,159..160,166..167,173,183..186,189,191,207,209..210,
                     217,221,228,235,239,241..242,244..245,269..270,275,279,
                     282..283,285..286,289..290,293..295,297..304,307..308,
                     310..311,315,355,359,362..363,368..369,418,420,424)
                     /site_type="other"
                     /note="tetramer interface [polypeptide binding]"
                     /db_xref="CDD:176464"
     Site            order(68,89,141,212,268,270,275)
                     /site_type="active"
                     /db_xref="CDD:176464"
     CDS             1..430
                     /gene="purB"
                     /locus_tag="lmo1773"
                     /coded_by="complement(NC_003210.1:1845044..1846336)"
                     /experiment="EXISTENCE:[PMID:19448609]"
                     /note="Catalyzes two discrete reactions in the de novo
                     synthesis of purines: the cleavage of adenylosuccinate and
                     succinylaminoimidazole carboxamide ribotide"
                     /transl_table=11
                     /db_xref="GeneID:985967"
CONTIG      join(WP_003733238.1:1..430)
ORIGIN      
        1 mlerytrkem gniwteqnry qawleveila ceawaelgdi pkedvakira nakfdvdrih
       61 eieletrhdv vaftrsvses lgaerkwvhy gltstdvvdt ansyllkqan eilrkdlenf
      121 iaiigekake hkytvtmgrt hgvhaepttf glklalwyee mkrnlerfnf aadgvefgki
      181 sgavgtyani dpfvetyvce klgttpapis tqtlqrdrha eylatlalia tsvekfavev
      241 ralqksevre veeffakgqk gssamphkrn pigsenvtgl arvirghmvt ayenvplwhe
      301 rdishssaer iilpdstill dyilnrfgni vknltvfpen mkrnmdrtlg liysqrvlla
      361 lidkglarea aydvvqpram eawekqvpfr elveqdatit enlsaeeiad cfdynyhlkn
      421 vdlifdrlgl