preprotein translocase subunit SecA [Listeria monocytogenes EGD-e].

LOCUS       NP_464111                776 aa            linear   CON 28-AUG-2016
ACCESSION   NP_464111
VERSION     NP_464111.1
DBLINK      BioProject: PRJNA61583
            Assembly: GCF_000196035.1
DBSOURCE    REFSEQ: accession NC_003210.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes EGD-e
  ORGANISM  Listeria monocytogenes EGD-e
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 776)
  AUTHORS   Toledo-Arana,A., Dussurget,O., Nikitas,G., Sesto,N.,
            Guet-Revillet,H., Balestrino,D., Loh,E., Gripenland,J., Tiensuu,T.,
            Vaitkevicius,K., Barthelemy,M., Vergassola,M., Nahori,M.A.,
            Soubigou,G., Regnault,B., Coppee,J.Y., Lecuit,M., Johansson,J. and
            Cossart,P.
  TITLE     The Listeria transcriptional landscape from saprophytism to
            virulence
  JOURNAL   Nature 459 (7249), 950-956 (2009)
   PUBMED   19448609
REFERENCE   2  (residues 1 to 776)
  AUTHORS   Chatterjee,S.S., Hossain,H., Otten,S., Kuenne,C., Kuchmina,K.,
            Machata,S., Domann,E., Chakraborty,T. and Hain,T.
  TITLE     Intracellular gene expression profile of Listeria monocytogenes
  JOURNAL   Infect. Immun. 74 (2), 1323-1338 (2006)
   PUBMED   16428782
REFERENCE   3  (residues 1 to 776)
  AUTHORS   Glaser,P., Frangeul,L., Buchrieser,C., Amend,A., Baquero,F.,
            Berche,P., Bloecker,H., Brandt,P., Chakraborty,T., Charbit,A.,
            Chetouani,F., Couve,E., de Daruvar,A., Dehoux,P., Domann,E.,
            Dominguez-Bernal,G., Duchaud,E., Durand,L., Dussurget,O.,
            Entian,K.-D., Fsihi,H., Garcia-Del Portillo,F., Garrido,P.,
            Gautier,L., Goebel,W., Gomez-Lopez,N., Hain,T., Hauf,J.,
            Jackson,D., Jones,L.-M., Karst,U., Kreft,J., Kuhn,M., Kunst,F.,
            Kurapkat,G., Madueno,E., Maitournam,A., Mata Vicente,J., Ng,E.,
            Nordsiek,G., Novella,S., de Pablos,B., Perez-Diaz,J.-C., Remmel,B.,
            Rose,M., Rusniok,C., Schlueter,T., Simoes,N., Tierrez,A.,
            Vazquez-Boland,J.-A., Voss,H., Wehland,J. and Cossart,P.
  TITLE     Comparative genomics of Listeria species
  JOURNAL   Science 294 (5543), 849-852 (2001)
   PUBMED   11679669
REFERENCE   4  (residues 1 to 776)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2001) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 776)
  AUTHORS   Glaser,P., Frangeul,L. and Rusniok,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-JUN-2001) Glaser P., Institut Pasteur, Genomique des
            Microorganismes Pathogenes, 25 rue du Docteur Roux, 75724 Paris
            Cedex 15, FRANCE
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from CAC98662.
            RefSeq Category: Reference Genome
                        FGS: First Genome sequenced
                        MOD: Model Organism
                        UPR: UniProt Genome
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..776
                     /organism="Listeria monocytogenes EGD-e"
                     /strain="EGD-e"
                     /db_xref="taxon:169963"
     Protein         1..776
                     /product="preprotein translocase subunit SecA"
                     /calculated_mol_wt=89304
     Region          1..776
                     /region_name="SecA2_Lm"
                     /note="accessory Sec system translocase SecA2; NF012136"
                     /db_xref="CDD:333724"
     CDS             1..776
                     /locus_tag="lmo0583"
                     /gene_synonym="azi; div"
                     /coded_by="NC_003210.1:620805..623135"
                     /experiment="EXISTENCE:[PMID:19448609]"
                     /note="functions in protein export; can interact with
                     acidic membrane phospholipids and the SecYEG protein
                     complex; binds to preproteins; binds to ATP and undergoes
                     a conformational change to promote membrane insertion of
                     SecA/bound preprotein; ATP hydrolysis appears to drive
                     release of the preprotein from SecA and deinsertion of
                     SecA from the membrane; additional proteins SecD/F/YajC
                     aid SecA recycling; exists in an equilibrium between
                     monomers and dimers; may possibly form higher order
                     oligomers; in some organisms, especially gram positive
                     pathogens, have paralogs that have been found to be
                     nonessential but do function in secretion of a subset of
                     exported proteins"
                     /transl_table=11
                     /db_xref="GeneID:984550"
CONTIG      join(WP_010989521.1:1..776)
ORIGIN      
        1 mrqnyddrki vkqyreiarq ivkkeglykn meqaelceqt nfwrekfktk pmtdrdkini
       61 falareaasr iigldavvvq ligalvlgdg kvaemktgeg ktlmslfvmf ievmrgnrvh
      121 lvtaneylar rdreeigqvl eylgvsvaln esgldiaqkk aiytadviyg tasefgfdyl
      181 rdnmvrqked kvqsgldfvl ideadsilid eartpllisd rkeedlslyh tanklvkkmm
      241 kddyemeehk rfvwlndagi ekaqkfwgve slysaeaqse lritmllmra hflmhkdkdy
      301 vvlddevlii dphtgralpg rrfndglhqa ieakegvevk eesrtlatit iqnyfrmykk
      361 isgmtgtakt eeeefrqiyn mdvvviptnl rvnredmqdd ifytkkekgr aivyevswry
      421 ekgqptligt ssiksnewis glldaagiph qvlnaknhaq eaeiiakagk rgmvtlatnm
      481 agrgtdikld pdvhklggla vigterhesr ridlqlmgrs grrgdpgfsk fmisleddll
      541 eqfeskswek lsaklkrkap rdgkpvnsrk ihavvvdaqk rleganydir kdllsydevi
      601 dlqrkmvyke rdlllernkl gvssekilre vaeysfihps dipeeeleiy ysrqkellgg
      661 tkfpisfdqv tlmeprevve eivswhkker nkfpaetiaa ierevylnlm dqmwvmhlda
      721 mvqlregihl raygqqdplv myqkegaqlf ekfqadyhfy fahalleldp dgliqg