toxin [Listeria monocytogenes EGD-e].

LOCUS       NP_463599                604 aa            linear   CON 28-AUG-2016
ACCESSION   NP_463599
VERSION     NP_463599.1
DBLINK      BioProject: PRJNA61583
            Assembly: GCF_000196035.1
DBSOURCE    REFSEQ: accession NC_003210.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes EGD-e
  ORGANISM  Listeria monocytogenes EGD-e
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 604)
  AUTHORS   Toledo-Arana,A., Dussurget,O., Nikitas,G., Sesto,N.,
            Guet-Revillet,H., Balestrino,D., Loh,E., Gripenland,J., Tiensuu,T.,
            Vaitkevicius,K., Barthelemy,M., Vergassola,M., Nahori,M.A.,
            Soubigou,G., Regnault,B., Coppee,J.Y., Lecuit,M., Johansson,J. and
            Cossart,P.
  TITLE     The Listeria transcriptional landscape from saprophytism to
            virulence
  JOURNAL   Nature 459 (7249), 950-956 (2009)
   PUBMED   19448609
REFERENCE   2  (residues 1 to 604)
  AUTHORS   Chatterjee,S.S., Hossain,H., Otten,S., Kuenne,C., Kuchmina,K.,
            Machata,S., Domann,E., Chakraborty,T. and Hain,T.
  TITLE     Intracellular gene expression profile of Listeria monocytogenes
  JOURNAL   Infect. Immun. 74 (2), 1323-1338 (2006)
   PUBMED   16428782
REFERENCE   3  (residues 1 to 604)
  AUTHORS   Glaser,P., Frangeul,L., Buchrieser,C., Amend,A., Baquero,F.,
            Berche,P., Bloecker,H., Brandt,P., Chakraborty,T., Charbit,A.,
            Chetouani,F., Couve,E., de Daruvar,A., Dehoux,P., Domann,E.,
            Dominguez-Bernal,G., Duchaud,E., Durand,L., Dussurget,O.,
            Entian,K.-D., Fsihi,H., Garcia-Del Portillo,F., Garrido,P.,
            Gautier,L., Goebel,W., Gomez-Lopez,N., Hain,T., Hauf,J.,
            Jackson,D., Jones,L.-M., Karst,U., Kreft,J., Kuhn,M., Kunst,F.,
            Kurapkat,G., Madueno,E., Maitournam,A., Mata Vicente,J., Ng,E.,
            Nordsiek,G., Novella,S., de Pablos,B., Perez-Diaz,J.-C., Remmel,B.,
            Rose,M., Rusniok,C., Schlueter,T., Simoes,N., Tierrez,A.,
            Vazquez-Boland,J.-A., Voss,H., Wehland,J. and Cossart,P.
  TITLE     Comparative genomics of Listeria species
  JOURNAL   Science 294 (5543), 849-852 (2001)
   PUBMED   11679669
REFERENCE   4  (residues 1 to 604)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2001) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 604)
  AUTHORS   Glaser,P., Frangeul,L. and Rusniok,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-JUN-2001) Glaser P., Institut Pasteur, Genomique des
            Microorganismes Pathogenes, 25 rue du Docteur Roux, 75724 Paris
            Cedex 15, FRANCE
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from CAC98281.
            RefSeq Category: Reference Genome
                        FGS: First Genome sequenced
                        MOD: Model Organism
                        UPR: UniProt Genome
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..604
                     /organism="Listeria monocytogenes EGD-e"
                     /strain="EGD-e"
                     /db_xref="taxon:169963"
     Protein         1..604
                     /product="toxin"
                     /calculated_mol_wt=66432
     Region          <244..291
                     /region_name="PT-TG"
                     /note="Pre-toxin TG; pfam14449"
                     /db_xref="CDD:433960"
     Region          430..604
                     /region_name="VIP2"
                     /note="A family of actin-ADP-ribosylating toxin. A member
                     of the Bacillus-prodiced vegetative insecticidal proteins
                     (VIPs) possesses high specificity against the major insect
                     pest, corn rootworms, and belongs to a classs of binary
                     toxins and regulators of...; cl00173"
                     /db_xref="CDD:469640"
     Site            order(456,470,504,537..539,576,585)
                     /site_type="active"
                     /db_xref="CDD:238144"
     Site            470
                     /site_type="active"
                     /note="conformational flexibility of ligand binding pocket
                     [active]"
                     /db_xref="CDD:238144"
     Site            order(571,574,576)
                     /site_type="active"
                     /note="ADP-ribosylating toxin turn-turn motif [active]"
                     /db_xref="CDD:238144"
     CDS             1..604
                     /locus_tag="lmo0066"
                     /coded_by="NC_003210.1:72408..74222"
                     /experiment="EXISTENCE:[PMID:19448609]"
                     /transl_table=11
                     /db_xref="GeneID:986392"
CONTIG      join(WP_010989332.1:1..604)
ORIGIN      
        1 mkevnyredd wreaksalap faaanwvggl fnnlekvskn meeaeedvqe ldsdhaisfq
       61 htnyrgkysa ieddlmvlyk fschagekme tlvdqpfyek ldafvdgmqd lsistysttn
      121 rigakskqty tttsggsqvi esikegatie dlmngdnfya nqmqlqyrdw qranpdqdvs
      181 kkdfqmgmlh srafeyksik deqqekefwv nivatvvivg vsifcppagl alavgygsle
      241 agsaisgkdw vsgrelstee ralrgglall divpgvkals tgakaasags klvrvgdnvl
      301 agsknvgkgt idngiqagkq amdlrlanak kvseavqkkl tkdlddigtm aktiqnktke
      361 tftlppreql afarggsipe qsatgaaaia akkklkdimq nmdnlnvkgg gkddiieqnk
      421 slkftslees ekwgidgfsv wrnslssrei qairdytdiw hygnmngylr gsveklapdn
      481 aeriknlssa lekaelpdni ilyrgtssei ldnfldlknl nyqnlvgkti eekgfmsttt
      541 isnqtfsgnv tmkinapkgs kgaylahfse tpeeaevlfn igqkmlikev telngkieii
      601 vdll