Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

putative superfamily I DNA helicases [Salmonella enterica subsp.


LOCUS       NP_463348               1171 aa            linear   CON 08-SEP-2022
            enterica serovar Typhimurium str. LT2].
ACCESSION   NP_463348
VERSION     NP_463348.1
DBLINK      BioProject: PRJNA57799
            BioSample: SAMN02604315
DBSOURCE    REFSEQ: accession NC_003197.2
KEYWORDS    RefSeq.
SOURCE      Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Salmonella.
REFERENCE   1  (residues 1 to 1171)
  AUTHORS   McClelland,M., Sanderson,K.E., Spieth,J., Clifton,S.W.,
            Latreille,P., Courtney,L., Porwollik,S., Ali,J., Dante,M., Du,F.,
            Hou,S., Layman,D., Leonard,S., Nguyen,C., Scott,K., Holmes,A.,
            Grewal,N., Mulvaney,E., Ryan,E., Sun,H., Florea,L., Miller,W.,
            Stoneking,T., Nhan,M., Waterston,R. and Wilson,R.K.
  TITLE     Complete genome sequence of Salmonella enterica serovar Typhimurium
            LT2
  JOURNAL   Nature 413 (6858), 852-856 (2001)
   PUBMED   11677609
REFERENCE   2  (residues 1 to 1171)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-SEP-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 1171)
  AUTHORS   McClelland,M., Jain,A., Saraogi,P., Mendelson,R., Westerman,R.,
            SanMiguel,P. and Csonka,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2016) Department of Microbiology and Molecular
            Genetics, University of California, Irvine, CA 92697, USA
  REMARK    Sequence update by submitter
REFERENCE   4  (residues 1 to 1171)
  CONSRTM   The Salmonella typhimurium Genome Sequencing Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-MAR-2001) Genome Sequencing Center, Department of
            Genetics, Washington University School of Medicine, 4444 Forest
            Park Boulevard, St. Louis, MO 63108, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AAL23307.
            Supported by NIH grant 5U 01 AI43283
            
            Coding sequences below are predicted from manually evaluated
            computer analysis, using similarity information and the programs;
            GLIMMER; http://www.tigr.org/softlab/glimmer/glimmer.html and
            GeneMark; http://opal.biology.gatech.edu/GeneMark/
            
            EC numbers were kindly provided by Junko Yabuzaki and the Kyoto
            Encyclopedia of Genes and Genomes; http://www.genome.ad.jp/kegg/,
            and Pedro Romero and Peter Karp at EcoCyc;
            http://ecocyc.PangeaSystems.com/ecocyc/
            
            The analyses of ribosome binding sites and promoter binding sites
            were kindly provided by Heladia Salgado, Julio Collado-Vides and
            ReguonDB;
            http://kinich.cifn.unam.mx:8850/db/regulondb_intro.frameset
            
            This sequence was finished as follows unless otherwise noted: all
            regions were double stranded, sequenced with an alternate
            chemistries or covered by high quality data (i.e., phred quality >=
            30); an attempt was made to resolve all sequencing problems, such
            as compressions and repeats; all regions were covered by sequence
            from more than one m13 subclone.
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..1171
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhimurium str. LT2"
                     /strain="LT2"
                     /serovar="Typhimurium"
                     /sub_species="enterica"
                     /culture_collection="ATCC:700720"
                     /culture_collection="SGSC:1412"
                     /type_material="type strain of Salmonella enterica"
                     /db_xref="taxon:99287"
                     /focus
     Protein         1..1171
                     /product="putative superfamily I DNA helicases"
                     /calculated_mol_wt=131645
     Region          150..988
                     /region_name="DNA2"
                     /note="Superfamily I DNA and/or RNA helicase [Replication,
                     recombination and repair]; COG1112"
                     /db_xref="CDD:440729"
     Region          1021..1169
                     /region_name="PLDc_yjhR_C_like"
                     /note="C-terminal domain of Escherichia coli
                     uncharacterized protein yjhR and similar proteins;
                     cd09118"
                     /db_xref="CDD:197217"
     Site            order(1114,1116,1129,1131,1145)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:197217"
     Site            1114
                     /site_type="active"
                     /note="catalytic site [active]"
                     /db_xref="CDD:197217"
     CDS             1..1171
                     /locus_tag="STM4489"
                     /coded_by="NC_003197.2:4731981..4735496"
                     /note="similar to E. coli putative frameshift suppressor
                     (AAC77264.1); Blastp hit to AAC77264.1 (338 aa), 68%
                     identity in aa 1 - 338"
                     /transl_table=11
                     /db_xref="GeneID:1256015"
CONTIG      join(WP_000342544.1:1..1171)
ORIGIN      
        1 mddnalgfas ywrnsladae sgkgsferkd aknfthwhgi aagrldetiv gkffegekdd
       61 vetvdvilrp kvyfrllqrg kdhsagapdi vtpivtpall sregflyptp atsiprdlle
      121 plpkgafsig eieqydkykt thtsfsinfd drvdktaetd eerearyaaw qqdwrqyldd
      181 serllknvvg dwiknpeqye laehgyivkt aqsggasfhi lslydhllvc kkdvplfnrf
      241 asrevhaaes llppeakfsd righsgdkfp lakaqrdals hfldarhgdi lavngppgtg
      301 kttlvlsiia tqwaraalek aeppviiats tnnqavtnii eafgkdfsqg tgamagrwlp
      361 elksfgayfp sstrkaeaak kyqtedffnq veskeyveda llfylekaka afpekecssp
      421 ekviellhgq laakseqlvr lnatwqtlsq vratrelidn dieqyldnln kllsgqeqkv
      481 tqlksakaew kkyrasesli yplfswlpvv rskrqyqiql fledklgali agnqwsdpet
      541 iernidrlln saereqttyr qqidsaheiv lkeqqaaqew qrlaldlghe gdeelsfsqa
      601 deladtqirf paflltthyw egrwlmdmag iddlqkekgk kgakgvtarw qrrmkltpcv
      661 vmtcymlpgn mqisehkgqr kfeksylydf adllivdeag qvlpevaaas falakkalvi
      721 gdteqippiw sitpaidign mlaekilsgs tqeeitekyt aiaelgksaa sgsvmkiaqc
      781 asryqydpel argmylyehr rcfdniigyc ntlcyhgkll pkrgceesnl mpamgylhid
      841 gkgelassgs rynlleaeti aawltdnqqs ieahygkslh evvgivtpfs aqvptikqal
      901 dkqgisagtn etsltvgtvh slqgaeraiv ifspvyskhe dgafidsdns mlnvavsrak
      961 dsflvfgdmd lfeiqpassp rgllakylfe seknaltfdy kerkdlktae tkiytlhgve
     1021 qhdnflnqtf entdkhitiv spwltwqkle qtgfldsmit acsrginvtv vtdrsynteh
     1081 ndfekrkekq qnlkaalekl nalgiatklv nrvhskivig ddgllcvgsf nwfsatrear
     1141 yerydtsmvy cgdnlkgeie aiynsldrrq v