enzyme in methyl-directed mismatch repair [Salmonella enterica

LOCUS       NP_463220                618 aa            linear   CON 08-SEP-2022
            subsp. enterica serovar Typhimurium str. LT2].
ACCESSION   NP_463220
VERSION     NP_463220.1
DBLINK      BioProject: PRJNA57799
            BioSample: SAMN02604315
DBSOURCE    REFSEQ: accession NC_003197.2
KEYWORDS    RefSeq.
SOURCE      Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Salmonella.
REFERENCE   1  (residues 1 to 618)
  AUTHORS   McClelland,M., Sanderson,K.E., Spieth,J., Clifton,S.W.,
            Latreille,P., Courtney,L., Porwollik,S., Ali,J., Dante,M., Du,F.,
            Hou,S., Layman,D., Leonard,S., Nguyen,C., Scott,K., Holmes,A.,
            Grewal,N., Mulvaney,E., Ryan,E., Sun,H., Florea,L., Miller,W.,
            Stoneking,T., Nhan,M., Waterston,R. and Wilson,R.K.
  TITLE     Complete genome sequence of Salmonella enterica serovar Typhimurium
            LT2
  JOURNAL   Nature 413 (6858), 852-856 (2001)
   PUBMED   11677609
REFERENCE   2  (residues 1 to 618)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-SEP-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 618)
  AUTHORS   McClelland,M., Jain,A., Saraogi,P., Mendelson,R., Westerman,R.,
            SanMiguel,P. and Csonka,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2016) Department of Microbiology and Molecular
            Genetics, University of California, Irvine, CA 92697, USA
  REMARK    Sequence update by submitter
REFERENCE   4  (residues 1 to 618)
  CONSRTM   The Salmonella typhimurium Genome Sequencing Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-MAR-2001) Genome Sequencing Center, Department of
            Genetics, Washington University School of Medicine, 4444 Forest
            Park Boulevard, St. Louis, MO 63108, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AAL23179.
            Supported by NIH grant 5U 01 AI43283
            
            Coding sequences below are predicted from manually evaluated
            computer analysis, using similarity information and the programs;
            GLIMMER; http://www.tigr.org/softlab/glimmer/glimmer.html and
            GeneMark; http://opal.biology.gatech.edu/GeneMark/
            
            EC numbers were kindly provided by Junko Yabuzaki and the Kyoto
            Encyclopedia of Genes and Genomes; http://www.genome.ad.jp/kegg/,
            and Pedro Romero and Peter Karp at EcoCyc;
            http://ecocyc.PangeaSystems.com/ecocyc/
            
            The analyses of ribosome binding sites and promoter binding sites
            were kindly provided by Heladia Salgado, Julio Collado-Vides and
            ReguonDB;
            http://kinich.cifn.unam.mx:8850/db/regulondb_intro.frameset
            
            This sequence was finished as follows unless otherwise noted: all
            regions were double stranded, sequenced with an alternate
            chemistries or covered by high quality data (i.e., phred quality >=
            30); an attempt was made to resolve all sequencing problems, such
            as compressions and repeats; all regions were covered by sequence
            from more than one m13 subclone.
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..618
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhimurium str. LT2"
                     /strain="LT2"
                     /serovar="Typhimurium"
                     /sub_species="enterica"
                     /culture_collection="ATCC:700720"
                     /culture_collection="SGSC:1412"
                     /type_material="type strain of Salmonella enterica"
                     /db_xref="taxon:99287"
                     /focus
     Protein         1..618
                     /product="enzyme in methyl-directed mismatch repair"
                     /calculated_mol_wt=67631
     Region          1..618
                     /region_name="mutL"
                     /note="DNA mismatch repair endonuclease MutL; PRK00095"
                     /db_xref="CDD:234630"
     CDS             1..618
                     /gene="mutL"
                     /locus_tag="STM4359"
                     /coded_by="NC_003197.2:4601709..4603565"
                     /note="stimulates binding of Vsr and MutS to heteroduplex
                     DNA; DNA mismatch repair protein MUTL. (SW:MUTL_SALTY)"
                     /transl_table=11
                     /db_xref="GeneID:1255885"
CONTIG      join(WP_001122538.1:1..618)
ORIGIN      
        1 mpiqvlppql anqiaagevv erpasvvkel vensldagat rvdidiergg aklirirdng
       61 cgikkeelal alarhatski aslddleaii slgfrgeala sissvsrltl tsrtaeqaea
      121 wqayaegrdm dvtvkpaahp vgttlevldl fyntparrkf mrtektefnh ideiirrial
      181 arfdvtlnls hngklvrqyr avakdgqker rlgaicgtpf leqalaiewq hgdltlrgwv
      241 adpnhtttal teiqycyvng rmmrdrlinh airqacedkl gadqqpafvl yleidphqvd
      301 vnvhpakhev rfhqsrlvhd fiyqgvlsvl qqqtetalpl eeiapaprhv qenriaagrn
      361 hfavpaepta arepatprys ggasggnggr qsaggwphaq pgyqkqqgev yrtllqtpta
      421 spapesvtpa ldghsqsfgr vltivggdca llehagtiql lslpvaerwl rqaqltpgqs
      481 pvcaqpllip lrlkvsadek aalqkaqsll gelgiefqsd aqhvtiravp lplrqqnlqi
      541 lipeligyla qqttfatvni aqwiarnvqs ehpqwsmaqa islladverl cpqlvkappg
      601 gllqpvdlhs amnalkhe