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acetylglutamate kinase [Salmonella enterica subsp. enterica serovar


LOCUS       NP_463002                258 aa            linear   CON 08-SEP-2022
            Typhimurium str. LT2].
ACCESSION   NP_463002
VERSION     NP_463002.3
DBLINK      BioProject: PRJNA57799
            BioSample: SAMN02604315
DBSOURCE    REFSEQ: accession NC_003197.2
KEYWORDS    RefSeq.
SOURCE      Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Salmonella.
REFERENCE   1  (residues 1 to 258)
  AUTHORS   McClelland,M., Sanderson,K.E., Spieth,J., Clifton,S.W.,
            Latreille,P., Courtney,L., Porwollik,S., Ali,J., Dante,M., Du,F.,
            Hou,S., Layman,D., Leonard,S., Nguyen,C., Scott,K., Holmes,A.,
            Grewal,N., Mulvaney,E., Ryan,E., Sun,H., Florea,L., Miller,W.,
            Stoneking,T., Nhan,M., Waterston,R. and Wilson,R.K.
  TITLE     Complete genome sequence of Salmonella enterica serovar Typhimurium
            LT2
  JOURNAL   Nature 413 (6858), 852-856 (2001)
   PUBMED   11677609
REFERENCE   2  (residues 1 to 258)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-SEP-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 258)
  AUTHORS   McClelland,M., Jain,A., Saraogi,P., Mendelson,R., Westerman,R.,
            SanMiguel,P. and Csonka,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2016) Department of Microbiology and Molecular
            Genetics, University of California, Irvine, CA 92697, USA
  REMARK    Sequence update by submitter
REFERENCE   4  (residues 1 to 258)
  CONSRTM   The Salmonella typhimurium Genome Sequencing Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-MAR-2001) Genome Sequencing Center, Department of
            Genetics, Washington University School of Medicine, 4444 Forest
            Park Boulevard, St. Louis, MO 63108, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AAL22961.
            
            On Dec 2, 2016 this sequence version replaced NP_463002.2.
            Supported by NIH grant 5U 01 AI43283
            
            Coding sequences below are predicted from manually evaluated
            computer analysis, using similarity information and the programs;
            GLIMMER; http://www.tigr.org/softlab/glimmer/glimmer.html and
            GeneMark; http://opal.biology.gatech.edu/GeneMark/
            
            EC numbers were kindly provided by Junko Yabuzaki and the Kyoto
            Encyclopedia of Genes and Genomes; http://www.genome.ad.jp/kegg/,
            and Pedro Romero and Peter Karp at EcoCyc;
            http://ecocyc.PangeaSystems.com/ecocyc/
            
            The analyses of ribosome binding sites and promoter binding sites
            were kindly provided by Heladia Salgado, Julio Collado-Vides and
            ReguonDB;
            http://kinich.cifn.unam.mx:8850/db/regulondb_intro.frameset
            
            This sequence was finished as follows unless otherwise noted: all
            regions were double stranded, sequenced with an alternate
            chemistries or covered by high quality data (i.e., phred quality >=
            30); an attempt was made to resolve all sequencing problems, such
            as compressions and repeats; all regions were covered by sequence
            from more than one m13 subclone.
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..258
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhimurium str. LT2"
                     /strain="LT2"
                     /serovar="Typhimurium"
                     /sub_species="enterica"
                     /culture_collection="ATCC:700720"
                     /culture_collection="SGSC:1412"
                     /type_material="type strain of Salmonella enterica"
                     /db_xref="taxon:99287"
                     /focus
     Protein         1..258
                     /product="acetylglutamate kinase"
                     /EC_number="2.7.2.8"
                     /calculated_mol_wt=26876
     Region          5..256
                     /region_name="AAK_NAGK-NC"
                     /note="N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC)
                     catalyzes the phosphorylation of the gamma-COOH group of
                     N-acetyl-L-glutamate (NAG) by ATP in the second step of
                     microbial arginine biosynthesis using the acetylated,
                     noncyclic route of ornithine...; cd04249"
                     /db_xref="CDD:239782"
     Site            order(8,10..11,44..45,180,186,209,211,217)
                     /site_type="other"
                     /note="nucleotide binding site [chemical binding]"
                     /db_xref="CDD:239782"
     Site            order(44..45,66,158..159,161)
                     /site_type="other"
                     /note="N-acetyl-L-glutamate binding site [chemical
                     binding]"
                     /db_xref="CDD:239782"
     CDS             1..258
                     /gene="argB"
                     /locus_tag="STM4122"
                     /coded_by="NC_003197.2:4340538..4341314"
                     /note="similar to E. coli acetylglutamate kinase
                     (AAC76941.1); Blastp hit to AAC76941.1 (258 aa), 94%
                     identity in aa 1 - 258"
                     /transl_table=11
                     /db_xref="GeneID:1255649"
CONTIG      join(WP_001575262.1:1..258)
ORIGIN      
        1 mmnpliiklg gvlldseeal erlftalvny reshqrplvi vhgggcvvde lmkglnlpvk
       61 kkdglrvtpa dqigiitgal agtanktlla wakkhhiasv glflgdgdsv nvtqldealg
      121 hvglaqpgsp klinmlleng flpvvssigv tddgqlmnvn adqaatalaa tlgadlills
      181 dvsgildgkg qriaemtask aeqlidqgii tdgmivkvna aldaaralgr pvdiaswrha
      241 eqlpalfngt pigtrila