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LOCUS NP_462991 833 aa linear CON 08-SEP-2022 serovar Typhimurium str. LT2]. ACCESSION NP_462991 VERSION NP_462991.1 DBLINK BioProject: PRJNA57799 BioSample: SAMN02604315 DBSOURCE REFSEQ: accession NC_003197.2 KEYWORDS RefSeq. SOURCE Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 ORGANISM Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Salmonella. REFERENCE 1 (residues 1 to 833) AUTHORS McClelland,M., Sanderson,K.E., Spieth,J., Clifton,S.W., Latreille,P., Courtney,L., Porwollik,S., Ali,J., Dante,M., Du,F., Hou,S., Layman,D., Leonard,S., Nguyen,C., Scott,K., Holmes,A., Grewal,N., Mulvaney,E., Ryan,E., Sun,H., Florea,L., Miller,W., Stoneking,T., Nhan,M., Waterston,R. and Wilson,R.K. TITLE Complete genome sequence of Salmonella enterica serovar Typhimurium LT2 JOURNAL Nature 413 (6858), 852-856 (2001) PUBMED 11677609 REFERENCE 2 (residues 1 to 833) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (08-SEP-2022) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 3 (residues 1 to 833) AUTHORS McClelland,M., Jain,A., Saraogi,P., Mendelson,R., Westerman,R., SanMiguel,P. and Csonka,L. TITLE Direct Submission JOURNAL Submitted (13-JAN-2016) Department of Microbiology and Molecular Genetics, University of California, Irvine, CA 92697, USA REMARK Sequence update by submitter REFERENCE 4 (residues 1 to 833) CONSRTM The Salmonella typhimurium Genome Sequencing Project TITLE Direct Submission JOURNAL Submitted (29-MAR-2001) Genome Sequencing Center, Department of Genetics, Washington University School of Medicine, 4444 Forest Park Boulevard, St. Louis, MO 63108, USA COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to AAL22950. Supported by NIH grant 5U 01 AI43283 Coding sequences below are predicted from manually evaluated computer analysis, using similarity information and the programs; GLIMMER; http://www.tigr.org/softlab/glimmer/glimmer.html and GeneMark; http://opal.biology.gatech.edu/GeneMark/ EC numbers were kindly provided by Junko Yabuzaki and the Kyoto Encyclopedia of Genes and Genomes; http://www.genome.ad.jp/kegg/, and Pedro Romero and Peter Karp at EcoCyc; http://ecocyc.PangeaSystems.com/ecocyc/ The analyses of ribosome binding sites and promoter binding sites were kindly provided by Heladia Salgado, Julio Collado-Vides and ReguonDB; http://kinich.cifn.unam.mx:8850/db/regulondb_intro.frameset This sequence was finished as follows unless otherwise noted: all regions were double stranded, sequenced with an alternate chemistries or covered by high quality data (i.e., phred quality >= 30); an attempt was made to resolve all sequencing problems, such as compressions and repeats; all regions were covered by sequence from more than one m13 subclone. Method: conceptual translation. FEATURES Location/Qualifiers source 1..833 /organism="Salmonella enterica subsp. enterica serovar Typhimurium str. LT2" /strain="LT2" /serovar="Typhimurium" /sub_species="enterica" /culture_collection="ATCC:700720" /culture_collection="SGSC:1412" /type_material="type strain of Salmonella enterica" /db_xref="taxon:99287" /focus Protein 1..833 /product="general PTS family enzyme I" /EC_number="2.7.3.9" /calculated_mol_wt=91952 Region 6..84 /region_name="PTS-HPr_like" /note="Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; cd00367" /db_xref="CDD:238217" Site 6..9 /site_type="other" /note="dimerization domain swap beta strand [polypeptide binding]" /db_xref="CDD:238217" Site order(15,17..18,20..21,25,28,48..51,54..55) /site_type="other" /note="regulatory protein interface [polypeptide binding]" /db_xref="CDD:238217" Site 16 /site_type="active" /db_xref="CDD:238217" Site 49 /site_type="other" /note="regulatory phosphorylation site [posttranslational modification]" /db_xref="CDD:238217" Region 118..684 /region_name="PtsA" /note="Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; COG1080" /db_xref="CDD:440698" Region 687..831 /region_name="PtsN" /note="Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) [Carbohydrate transport and metabolism, Signal transduction mechanisms]; COG1762" /db_xref="CDD:441368" CDS 1..833 /gene="ptsA" /locus_tag="STM4110" /coded_by="complement(NC_003197.2:4324504..4327005)" /note="similar to E. coli PEP-protein phosphotransferase system enzyme I (AAC76929.1); Blastp hit to AAC76929.1 (711 aa), 90% identity in aa 1 - 711" /transl_table=11 /db_xref="GeneID:1255637" CONTIG join(WP_001128495.1:1..833) ORIGIN 1 mpliveftce lpngvharpa shvetlcntf tsqiewhnlr tdrkgsaksa laligtdtla 61 gdhcqlvisg adeqvacqrl sqwlrdefpl cdaplaeikn seleplpasl tqlnpqiyra 121 rsvcsgsagg vltplssldl nalgelptan dteteqaald nglamlikhi efrqldsdga 181 asaileahrs lagdaslrqh lldgvlrgls caqaivesan hfcnefaras ssylqerald 241 vrdvcfqllq hiyggqrfpa pgqltrpsic maeeltpsqf leldktflkg lllksggtts 301 htvilarsfn iptlvgveie altpwrqqtv yidgnagaiv vapdepvtry yqqearvqda 361 lreqqriwlt qeartadgir mevaaniahs veaqaafsng aeavglfrte mlymdracap 421 denelynifc qalesakgrs iivrtmdigg dkpvdylnip aeanpflgyr avriyeeyas 481 lfttqlrsil rasahgnlki mipmissmee ilwvkeklae akqqlrnehi pfdekiplgi 541 mlevpsvmfi idqcceeidf fsigsndltq yllavdrdna kvtrhynsln paflraldfa 601 vqavhrqgkw iglcgelgak gsvlpllvgl gldeismgap sipaakarma qldsracrql 661 lnqamacrts levehllaqf rmsqqdaplv taqcitldsd wrskeevikg mtdnlllagr 721 cryprklead lwareavfst glgfsfaiph sksehieqst isvarlnapv rwgddeaqfi 781 imltlnkhaa gdqhmrifsr larrimheef rntlvnaasa daiasllqhe lel