Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

dihydroxyacid dehydratase [Salmonella enterica subsp. enterica


LOCUS       NP_462795                616 aa            linear   CON 08-SEP-2022
            serovar Typhimurium str. LT2].
ACCESSION   NP_462795
VERSION     NP_462795.1
DBLINK      BioProject: PRJNA57799
            BioSample: SAMN02604315
DBSOURCE    REFSEQ: accession NC_003197.2
KEYWORDS    RefSeq.
SOURCE      Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Salmonella.
REFERENCE   1  (residues 1 to 616)
  AUTHORS   McClelland,M., Sanderson,K.E., Spieth,J., Clifton,S.W.,
            Latreille,P., Courtney,L., Porwollik,S., Ali,J., Dante,M., Du,F.,
            Hou,S., Layman,D., Leonard,S., Nguyen,C., Scott,K., Holmes,A.,
            Grewal,N., Mulvaney,E., Ryan,E., Sun,H., Florea,L., Miller,W.,
            Stoneking,T., Nhan,M., Waterston,R. and Wilson,R.K.
  TITLE     Complete genome sequence of Salmonella enterica serovar Typhimurium
            LT2
  JOURNAL   Nature 413 (6858), 852-856 (2001)
   PUBMED   11677609
REFERENCE   2  (residues 1 to 616)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-SEP-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 616)
  AUTHORS   McClelland,M., Jain,A., Saraogi,P., Mendelson,R., Westerman,R.,
            SanMiguel,P. and Csonka,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2016) Department of Microbiology and Molecular
            Genetics, University of California, Irvine, CA 92697, USA
  REMARK    Sequence update by submitter
REFERENCE   4  (residues 1 to 616)
  CONSRTM   The Salmonella typhimurium Genome Sequencing Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-MAR-2001) Genome Sequencing Center, Department of
            Genetics, Washington University School of Medicine, 4444 Forest
            Park Boulevard, St. Louis, MO 63108, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AAL22754.
            Supported by NIH grant 5U 01 AI43283
            
            Coding sequences below are predicted from manually evaluated
            computer analysis, using similarity information and the programs;
            GLIMMER; http://www.tigr.org/softlab/glimmer/glimmer.html and
            GeneMark; http://opal.biology.gatech.edu/GeneMark/
            
            EC numbers were kindly provided by Junko Yabuzaki and the Kyoto
            Encyclopedia of Genes and Genomes; http://www.genome.ad.jp/kegg/,
            and Pedro Romero and Peter Karp at EcoCyc;
            http://ecocyc.PangeaSystems.com/ecocyc/
            
            The analyses of ribosome binding sites and promoter binding sites
            were kindly provided by Heladia Salgado, Julio Collado-Vides and
            ReguonDB;
            http://kinich.cifn.unam.mx:8850/db/regulondb_intro.frameset
            
            This sequence was finished as follows unless otherwise noted: all
            regions were double stranded, sequenced with an alternate
            chemistries or covered by high quality data (i.e., phred quality >=
            30); an attempt was made to resolve all sequencing problems, such
            as compressions and repeats; all regions were covered by sequence
            from more than one m13 subclone.
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..616
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhimurium str. LT2"
                     /strain="LT2"
                     /serovar="Typhimurium"
                     /sub_species="enterica"
                     /culture_collection="ATCC:700720"
                     /culture_collection="SGSC:1412"
                     /type_material="type strain of Salmonella enterica"
                     /db_xref="taxon:99287"
                     /focus
     Protein         1..616
                     /product="dihydroxyacid dehydratase"
                     /EC_number="4.2.1.9"
                     /calculated_mol_wt=65571
     Region          2..616
                     /region_name="PRK12448"
                     /note="dihydroxy-acid dehydratase; Provisional"
                     /db_xref="CDD:237104"
     CDS             1..616
                     /gene="ilvD"
                     /locus_tag="STM3904"
                     /coded_by="NC_003197.2:4112000..4113850"
                     /note="dihydroxy-acid dehydratase. (SW:ILVD_SALTY)"
                     /transl_table=11
                     /db_xref="GeneID:1255430"
CONTIG      join(WP_001127434.1:1..616)
ORIGIN      
        1 mpkyrsattt hgrnmagara lwratgmtds dfgkpiiavv nsftqfvpgh vhlrdlgklv
       61 aeqieasggv akefntiavd dgiamghggm lyslpsreli adsveymvna hcadamvcis
      121 ncdkitpgml maslrlnipv ifvsggpmea gktklsdkii kldlvdamiq gadpkvsddq
      181 snqversacp tcgscsgmft ansmncltea lglsqpgngs llathadrkq lflnagkriv
      241 eltkryyeqn desalprnia skaafenamt ldiamggstn tvlhllaaaq eaeidftmsd
      301 idklsrkvpq lckvapstqk yhmedvhrag gvlgilgeld ragllnrnvk nvlgltlpqt
      361 leqyditvtq deavkkmfra gpagirttqa fsqdcrwdsl dddraagcir sleyayskdg
      421 glavlygnfa engcivktag vddsilkftg pakvyesqdd aveailggkv vegdvvviry
      481 egpkggpgmq emlyptsflk smglgkacal itdgrfsggt sglsighvsp eaasggtial
      541 iedgdtiaid ipnrsiqlql seaeiaarre aqeargdkaw tpknrqrqvs falrayasla
      601 tsadkgavrd ksklgg