Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

(p)ppGpp synthetase I [Salmonella enterica subsp. enterica serovar


LOCUS       NP_461877                744 aa            linear   CON 08-SEP-2022
            Typhimurium str. LT2].
ACCESSION   NP_461877
VERSION     NP_461877.1
DBLINK      BioProject: PRJNA57799
            BioSample: SAMN02604315
DBSOURCE    REFSEQ: accession NC_003197.2
KEYWORDS    RefSeq.
SOURCE      Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Salmonella.
REFERENCE   1  (residues 1 to 744)
  AUTHORS   McClelland,M., Sanderson,K.E., Spieth,J., Clifton,S.W.,
            Latreille,P., Courtney,L., Porwollik,S., Ali,J., Dante,M., Du,F.,
            Hou,S., Layman,D., Leonard,S., Nguyen,C., Scott,K., Holmes,A.,
            Grewal,N., Mulvaney,E., Ryan,E., Sun,H., Florea,L., Miller,W.,
            Stoneking,T., Nhan,M., Waterston,R. and Wilson,R.K.
  TITLE     Complete genome sequence of Salmonella enterica serovar Typhimurium
            LT2
  JOURNAL   Nature 413 (6858), 852-856 (2001)
   PUBMED   11677609
REFERENCE   2  (residues 1 to 744)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-SEP-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 744)
  AUTHORS   McClelland,M., Jain,A., Saraogi,P., Mendelson,R., Westerman,R.,
            SanMiguel,P. and Csonka,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2016) Department of Microbiology and Molecular
            Genetics, University of California, Irvine, CA 92697, USA
  REMARK    Sequence update by submitter
REFERENCE   4  (residues 1 to 744)
  CONSRTM   The Salmonella typhimurium Genome Sequencing Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-MAR-2001) Genome Sequencing Center, Department of
            Genetics, Washington University School of Medicine, 4444 Forest
            Park Boulevard, St. Louis, MO 63108, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AAL21836.
            Supported by NIH grant 5U 01 AI43283
            
            Coding sequences below are predicted from manually evaluated
            computer analysis, using similarity information and the programs;
            GLIMMER; http://www.tigr.org/softlab/glimmer/glimmer.html and
            GeneMark; http://opal.biology.gatech.edu/GeneMark/
            
            EC numbers were kindly provided by Junko Yabuzaki and the Kyoto
            Encyclopedia of Genes and Genomes; http://www.genome.ad.jp/kegg/,
            and Pedro Romero and Peter Karp at EcoCyc;
            http://ecocyc.PangeaSystems.com/ecocyc/
            
            The analyses of ribosome binding sites and promoter binding sites
            were kindly provided by Heladia Salgado, Julio Collado-Vides and
            ReguonDB;
            http://kinich.cifn.unam.mx:8850/db/regulondb_intro.frameset
            
            This sequence was finished as follows unless otherwise noted: all
            regions were double stranded, sequenced with an alternate
            chemistries or covered by high quality data (i.e., phred quality >=
            30); an attempt was made to resolve all sequencing problems, such
            as compressions and repeats; all regions were covered by sequence
            from more than one m13 subclone.
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..744
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhimurium str. LT2"
                     /strain="LT2"
                     /serovar="Typhimurium"
                     /sub_species="enterica"
                     /culture_collection="ATCC:700720"
                     /culture_collection="SGSC:1412"
                     /type_material="type strain of Salmonella enterica"
                     /db_xref="taxon:99287"
                     /focus
     Protein         1..744
                     /product="(p)ppGpp synthetase I"
                     /EC_number="2.7.6.5"
                     /calculated_mol_wt=83983
     Region          1..743
                     /region_name="relA"
                     /note="(p)ppGpp synthetase I/GTP pyrophosphokinase;
                     Provisional; PRK10872"
                     /db_xref="CDD:182797"
     CDS             1..744
                     /gene="relA"
                     /locus_tag="STM2956"
                     /coded_by="complement(NC_003197.2:3102887..3105121)"
                     /note="similar to E. coli (p)ppGpp synthetase I (GTP
                     pyrophosphokinase); regulation of RNA synthesis; stringent
                     factor (AAC75826.1); Blastp hit to AAC75826.1 (744 aa),
                     96% identity in aa 1 - 743"
                     /transl_table=11
                     /db_xref="GeneID:1254479"
CONTIG      join(WP_000226838.1:1..744)
ORIGIN      
        1 mvavrsahin kagefdpkkw iaslgissqq scerlaetwa yclqqtqghp dadlllwrgv
       61 emveilstls mdidtlraal lfpladanvv sedvlresvg ksivtlihgv rdmaairqln
      121 athndsvsse qvdnvrrmll amvddfrcvv iklaeriahl revkeapede rvlaakectn
      181 iyaplanrlg igqlkweled ycfrylhpae ykriakllhe rrldrehyie efvghlraem
      241 knegvqaevy grpkhiysiw rkmqkkhlaf delfdvravr ivaerlqdcy aalgivhthy
      301 rhlpdefddy vanpkpngyq sihtvvlgpg gktveiqirt kqmhedaelg vaahwkykeg
      361 aasggvrsgh edriawlrkl iawqeemads gemldevrsq vfddrvyvft pkgdvvdlpa
      421 gstpldfayh ihsdvghrci gakiggrivp ftyqlqmgdq ieiitqkqpn psrdwlnpnl
      481 gyvttsrgrs kihawfrkqd rdkniqagrq ilddelahlg islkeaekhl lprynfnele
      541 ellaaigggd irlnqmvnfl qsqfnkpsae eqdaaalkql qqktyapqnr rkddgrvvve
      601 gvgnlmhhia rccqpipgde ivgfitqgrg isvhradceq laelrshape riveavwges
      661 ysagyslvvr vqandrsgll rdittilane kvnvlgvasr sdikqqiati dmtieiynlq
      721 vlgrvlgkln qvpdvidarr lhgg