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putative diguanylate cyclase/phosphodiesterase domain 1 containing


LOCUS       NP_461351                729 aa            linear   CON 08-SEP-2022
            protein [Salmonella enterica subsp. enterica serovar Typhimurium
            str. LT2].
ACCESSION   NP_461351
VERSION     NP_461351.1
DBLINK      BioProject: PRJNA57799
            BioSample: SAMN02604315
DBSOURCE    REFSEQ: accession NC_003197.2
KEYWORDS    RefSeq.
SOURCE      Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Salmonella.
REFERENCE   1  (residues 1 to 729)
  AUTHORS   McClelland,M., Sanderson,K.E., Spieth,J., Clifton,S.W.,
            Latreille,P., Courtney,L., Porwollik,S., Ali,J., Dante,M., Du,F.,
            Hou,S., Layman,D., Leonard,S., Nguyen,C., Scott,K., Holmes,A.,
            Grewal,N., Mulvaney,E., Ryan,E., Sun,H., Florea,L., Miller,W.,
            Stoneking,T., Nhan,M., Waterston,R. and Wilson,R.K.
  TITLE     Complete genome sequence of Salmonella enterica serovar Typhimurium
            LT2
  JOURNAL   Nature 413 (6858), 852-856 (2001)
   PUBMED   11677609
REFERENCE   2  (residues 1 to 729)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-SEP-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 729)
  AUTHORS   McClelland,M., Jain,A., Saraogi,P., Mendelson,R., Westerman,R.,
            SanMiguel,P. and Csonka,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2016) Department of Microbiology and Molecular
            Genetics, University of California, Irvine, CA 92697, USA
  REMARK    Sequence update by submitter
REFERENCE   4  (residues 1 to 729)
  CONSRTM   The Salmonella typhimurium Genome Sequencing Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-MAR-2001) Genome Sequencing Center, Department of
            Genetics, Washington University School of Medicine, 4444 Forest
            Park Boulevard, St. Louis, MO 63108, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AAL21310.
            Supported by NIH grant 5U 01 AI43283
            
            Coding sequences below are predicted from manually evaluated
            computer analysis, using similarity information and the programs;
            GLIMMER; http://www.tigr.org/softlab/glimmer/glimmer.html and
            GeneMark; http://opal.biology.gatech.edu/GeneMark/
            
            EC numbers were kindly provided by Junko Yabuzaki and the Kyoto
            Encyclopedia of Genes and Genomes; http://www.genome.ad.jp/kegg/,
            and Pedro Romero and Peter Karp at EcoCyc;
            http://ecocyc.PangeaSystems.com/ecocyc/
            
            The analyses of ribosome binding sites and promoter binding sites
            were kindly provided by Heladia Salgado, Julio Collado-Vides and
            ReguonDB;
            http://kinich.cifn.unam.mx:8850/db/regulondb_intro.frameset
            
            This sequence was finished as follows unless otherwise noted: all
            regions were double stranded, sequenced with an alternate
            chemistries or covered by high quality data (i.e., phred quality >=
            30); an attempt was made to resolve all sequencing problems, such
            as compressions and repeats; all regions were covered by sequence
            from more than one m13 subclone.
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..729
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhimurium str. LT2"
                     /strain="LT2"
                     /serovar="Typhimurium"
                     /sub_species="enterica"
                     /culture_collection="ATCC:700720"
                     /culture_collection="SGSC:1412"
                     /type_material="type strain of Salmonella enterica"
                     /db_xref="taxon:99287"
                     /focus
     Protein         1..729
                     /product="putative diguanylate cyclase/phosphodiesterase
                     domain 1 containing protein"
                     /calculated_mol_wt=83066
     Region          163..727
                     /region_name="EAL"
                     /note="EAL domain, c-di-GMP-specific phosphodiesterase
                     class I (or its enzymatically inactive variant) [Signal
                     transduction mechanisms]; COG2200"
                     /db_xref="CDD:441802"
     Region          495..727
                     /region_name="EAL"
                     /note="EAL domain. This domain is found in diverse
                     bacterial signaling proteins. It is called EAL after its
                     conserved residues and is also known as domain of unknown
                     function 2 (DUF2). The EAL domain has been shown to
                     stimulate degradation of a second...; cd01948"
                     /db_xref="CDD:238923"
     CDS             1..729
                     /gene="yfeA"
                     /locus_tag="STM2410"
                     /coded_by="complement(NC_003197.2:2526557..2528746)"
                     /note="diguanylate cyclase/phosphodiesterase domain 2;
                     similar to E. coli orf, hypothetical protein (AAC75454.1);
                     Blastp hit to AAC75454.1 (768 aa), 68% identity in aa 45 -
                     766"
                     /transl_table=11
                     /db_xref="GeneID:1253932"
CONTIG      join(WP_001112946.1:1..729)
ORIGIN      
        1 mpdkcnvlkn ikifllafcl tvpaillsrl ispratidss yiflawlplc vmfsvlflfg
       61 rrgvapmvgg mmltnewnfh lplpqamvll fcqtfpvllv caivrwqlga rwrygipnqg
      121 iwlrvfwlgl mtpfgikism hlaghylafp vtistffgtg taifsivdll slisaalift
      181 lffyyplrmi vsphymrifw rrdvapylak ekrlftllwf atlatllavl ctpfetkyia
      241 gylvpvlfig ftigvgkisy pllnfswalt alfllsynrn flqgvgseys lafilsvlis
      301 fsicllymar inqrsewlnr qwhsqaltdp ltqlpnlral eqfllqdagq svcylrmenl
      361 eflsrhygmq mrvhcerevf rmlqplllek ekifhlpgse lllvltgpet earlqymlnv
      421 lnnrkiywnn tgldmeygas wgtfdgrqet lqpllgqlsw laeqscshrr vlaltqsiea
      481 asgqttervl rlqkirqale rgalvlyaqp irdaqgkgyd eiltrlrcdd gimmpnqfip
      541 liaqfnlsir fdmqvmeall qwlsahpsae qgarfsvnlm pltllqketa srimqlfkry
      601 gvppasviie iteeqafshs eismhninql rkfglkiaid dfgtgyanye rlkrlkadii
      661 kidgcfvkdi ltdsldamiv ksitdlakak slsvvaefve tpaqrdlllq lgvhslqgyl
      721 igrprplgk