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LOCUS NP_461214 878 aa linear CON 08-SEP-2022 Typhimurium str. LT2]. ACCESSION NP_461214 VERSION NP_461214.1 DBLINK BioProject: PRJNA57799 BioSample: SAMN02604315 DBSOURCE REFSEQ: accession NC_003197.2 KEYWORDS RefSeq. SOURCE Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 ORGANISM Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Salmonella. REFERENCE 1 (residues 1 to 878) AUTHORS McClelland,M., Sanderson,K.E., Spieth,J., Clifton,S.W., Latreille,P., Courtney,L., Porwollik,S., Ali,J., Dante,M., Du,F., Hou,S., Layman,D., Leonard,S., Nguyen,C., Scott,K., Holmes,A., Grewal,N., Mulvaney,E., Ryan,E., Sun,H., Florea,L., Miller,W., Stoneking,T., Nhan,M., Waterston,R. and Wilson,R.K. TITLE Complete genome sequence of Salmonella enterica serovar Typhimurium LT2 JOURNAL Nature 413 (6858), 852-856 (2001) PUBMED 11677609 REFERENCE 2 (residues 1 to 878) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (08-SEP-2022) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 3 (residues 1 to 878) AUTHORS McClelland,M., Jain,A., Saraogi,P., Mendelson,R., Westerman,R., SanMiguel,P. and Csonka,L. TITLE Direct Submission JOURNAL Submitted (13-JAN-2016) Department of Microbiology and Molecular Genetics, University of California, Irvine, CA 92697, USA REMARK Sequence update by submitter REFERENCE 4 (residues 1 to 878) CONSRTM The Salmonella typhimurium Genome Sequencing Project TITLE Direct Submission JOURNAL Submitted (29-MAR-2001) Genome Sequencing Center, Department of Genetics, Washington University School of Medicine, 4444 Forest Park Boulevard, St. Louis, MO 63108, USA COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to AAL21173. Supported by NIH grant 5U 01 AI43283 Coding sequences below are predicted from manually evaluated computer analysis, using similarity information and the programs; GLIMMER; http://www.tigr.org/softlab/glimmer/glimmer.html and GeneMark; http://opal.biology.gatech.edu/GeneMark/ EC numbers were kindly provided by Junko Yabuzaki and the Kyoto Encyclopedia of Genes and Genomes; http://www.genome.ad.jp/kegg/, and Pedro Romero and Peter Karp at EcoCyc; http://ecocyc.PangeaSystems.com/ecocyc/ The analyses of ribosome binding sites and promoter binding sites were kindly provided by Heladia Salgado, Julio Collado-Vides and ReguonDB; http://kinich.cifn.unam.mx:8850/db/regulondb_intro.frameset This sequence was finished as follows unless otherwise noted: all regions were double stranded, sequenced with an alternate chemistries or covered by high quality data (i.e., phred quality >= 30); an attempt was made to resolve all sequencing problems, such as compressions and repeats; all regions were covered by sequence from more than one m13 subclone. Method: conceptual translation. FEATURES Location/Qualifiers source 1..878 /organism="Salmonella enterica subsp. enterica serovar Typhimurium str. LT2" /strain="LT2" /serovar="Typhimurium" /sub_species="enterica" /culture_collection="ATCC:700720" /culture_collection="SGSC:1412" /type_material="type strain of Salmonella enterica" /db_xref="taxon:99287" /focus Protein 1..878 /product="DNA gyrase, subunit A" /EC_number="5.6.2.2" /calculated_mol_wt=96933 Region 7..842 /region_name="PRK05560" /note="DNA gyrase subunit A; Validated" /db_xref="CDD:235502" Region 538..585 /region_name="GyrA_CTD repeat" /note="GyrA_CTD repeat [structural motif]" /db_xref="CDD:293790" Region 588..638 /region_name="GyrA_CTD repeat" /note="GyrA_CTD repeat [structural motif]" /db_xref="CDD:293790" Region 644..688 /region_name="GyrA_CTD repeat" /note="GyrA_CTD repeat [structural motif]" /db_xref="CDD:293790" Region 692..739 /region_name="GyrA_CTD repeat" /note="GyrA_CTD repeat [structural motif]" /db_xref="CDD:293790" Region 742..790 /region_name="GyrA_CTD repeat" /note="GyrA_CTD repeat [structural motif]" /db_xref="CDD:293790" CDS 1..878 /gene="gyrA" /locus_tag="STM2272" /coded_by="complement(NC_003197.2:2373710..2376346)" /note="type II topoisomerase; similar to E. coli DNA gyrase, subunit A, type II topoisomerase (AAC75291.1); Blastp hit to AAC75291.1 (875 aa), 91% identity in aa 1 - 875" /transl_table=11 /db_xref="GeneID:1253794" CONTIG join(WP_001281271.1:1..878) ORIGIN 1 msdlareitp vnieeelkss yldyamsviv gralpdvrdg lkpvhrrvly amnvlgndwn 61 kaykksarvv gdvigkyhph gdsavydtiv rmaqpfslry mlvdgqgnfg sidgdsaaam 121 ryteirlaki ahelmadlek etvdfvdnyd gtekipdvmp tkipnllvng ssgiavgmat 181 nipphnltev ingclayidn edisieglme hipgpdfpta aiingrrgie eayrtgrgkv 241 yiraraevea daktgretii vheipyqvnk arliekiael vkdkrvegis alrdesdkdg 301 mrivievkrd avgevvlnnl ysqtqlqvsf ginmvalhhg qpkimnlkdi isafvrhrre 361 vvtrrtifel rkardrahil ealaialani dpiielirra ptpaeakaal isrpwdlgnv 421 aamleragdd aarpewlepe fgvrdgqyyl teqqaqaild lrlqkltgle heklldeyke 481 lleqiaellh ilgsadrlme vireemelir dqfgderrte itansadini edlisqedvv 541 vtlshqgyvk yqpltdyeaq rrggkgksaa rikeedfidr llvanthdti lcfssrgrly 601 wmkvyqlpea srgargrpiv nllpleaner itailpvrey eegvnvfmat asgtvkktal 661 tefsrprsag iiavnlndgd eligvdltsg sdevmlfsaa gkvvrfkeda vramgrtatg 721 vrgiklagdd kvvsliiprg egailtvtqn gygkrtaade yptksratqg visikvtern 781 gsvvgavqvd dcdqimmitd agtlvrtrvs eisvvgrntq gvilirtaed envvglqrva 841 epvddeelda idgsvaegde diapeaesdd dvaddade