Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

sensory histidine kinase in two-component regulatory system with


LOCUS       NP_461213                948 aa            linear   CON 08-SEP-2022
            RcsB [Salmonella enterica subsp. enterica serovar Typhimurium str.
            LT2].
ACCESSION   NP_461213
VERSION     NP_461213.1
DBLINK      BioProject: PRJNA57799
            BioSample: SAMN02604315
DBSOURCE    REFSEQ: accession NC_003197.2
KEYWORDS    RefSeq.
SOURCE      Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Salmonella.
REFERENCE   1  (residues 1 to 948)
  AUTHORS   McClelland,M., Sanderson,K.E., Spieth,J., Clifton,S.W.,
            Latreille,P., Courtney,L., Porwollik,S., Ali,J., Dante,M., Du,F.,
            Hou,S., Layman,D., Leonard,S., Nguyen,C., Scott,K., Holmes,A.,
            Grewal,N., Mulvaney,E., Ryan,E., Sun,H., Florea,L., Miller,W.,
            Stoneking,T., Nhan,M., Waterston,R. and Wilson,R.K.
  TITLE     Complete genome sequence of Salmonella enterica serovar Typhimurium
            LT2
  JOURNAL   Nature 413 (6858), 852-856 (2001)
   PUBMED   11677609
REFERENCE   2  (residues 1 to 948)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-SEP-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 948)
  AUTHORS   McClelland,M., Jain,A., Saraogi,P., Mendelson,R., Westerman,R.,
            SanMiguel,P. and Csonka,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2016) Department of Microbiology and Molecular
            Genetics, University of California, Irvine, CA 92697, USA
  REMARK    Sequence update by submitter
REFERENCE   4  (residues 1 to 948)
  CONSRTM   The Salmonella typhimurium Genome Sequencing Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-MAR-2001) Genome Sequencing Center, Department of
            Genetics, Washington University School of Medicine, 4444 Forest
            Park Boulevard, St. Louis, MO 63108, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AAL21172.
            Supported by NIH grant 5U 01 AI43283
            
            Coding sequences below are predicted from manually evaluated
            computer analysis, using similarity information and the programs;
            GLIMMER; http://www.tigr.org/softlab/glimmer/glimmer.html and
            GeneMark; http://opal.biology.gatech.edu/GeneMark/
            
            EC numbers were kindly provided by Junko Yabuzaki and the Kyoto
            Encyclopedia of Genes and Genomes; http://www.genome.ad.jp/kegg/,
            and Pedro Romero and Peter Karp at EcoCyc;
            http://ecocyc.PangeaSystems.com/ecocyc/
            
            The analyses of ribosome binding sites and promoter binding sites
            were kindly provided by Heladia Salgado, Julio Collado-Vides and
            ReguonDB;
            http://kinich.cifn.unam.mx:8850/db/regulondb_intro.frameset
            
            This sequence was finished as follows unless otherwise noted: all
            regions were double stranded, sequenced with an alternate
            chemistries or covered by high quality data (i.e., phred quality >=
            30); an attempt was made to resolve all sequencing problems, such
            as compressions and repeats; all regions were covered by sequence
            from more than one m13 subclone.
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..948
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhimurium str. LT2"
                     /strain="LT2"
                     /serovar="Typhimurium"
                     /sub_species="enterica"
                     /culture_collection="ATCC:700720"
                     /culture_collection="SGSC:1412"
                     /type_material="type strain of Salmonella enterica"
                     /db_xref="taxon:99287"
                     /focus
     Protein         1..948
                     /product="sensory histidine kinase in two-component
                     regulatory system with RcsB"
                     /EC_number="2.7.3.-"
                     /calculated_mol_wt=106149
     Region          31..947
                     /region_name="PRK10841"
                     /note="two-component system sensor histidine kinase RcsC"
                     /db_xref="CDD:182772"
     CDS             1..948
                     /gene="rcsC"
                     /locus_tag="STM2271"
                     /coded_by="complement(NC_003197.2:2370746..2373592)"
                     /note="regulates colanic capsule biosynthesis; similar to
                     E. coli sensor for ctr capsule biosynthesis, probable
                     histidine kinase acting on RcsB (AAC75278.1); Blastp hit
                     to AAC75278.1 (933 aa), 89% identity in aa 1 - 931"
                     /transl_table=11
                     /db_xref="GeneID:1253793"
CONTIG      join(WP_000876078.1:1..948)
ORIGIN      
        1 mkylasfrtt lkvsrylfra lalliwllia fvsvfyivna lhqreseirq efnlssdqaq
       61 rfiqrtsdvm kelkyiaenr ltaengvmss rarddkmvvp dfeplfadsd caamgsawrg
      121 sleslawfmr ywrdnfsaay dlnrvfligs dnlcmanfgl rempverdda lkalherimk
      181 yrnapqeesg nnlfwisqga rqgvgyfyal tpvylanrlq allgveqsir menfftpgsl
      241 pmgvtiiden ghslisltgp dgiikaeprw mqerswfgyt pgfrelvlkk slppsslsiv
      301 ysvpvdlvle rirililnai llnvlvgagl ftlarmyerr ifipaesdaq rleeheqfnr
      361 kivasapvgi cilrtidgvn ilsnelahty lnmlthedrq rltqiicgqq vnfvdvltsn
      421 ntnlqisfvh sryrnenvai cvlvdvstrv kmeeslqema qaaeqasqsk smflatvshe
      481 lrtplygiig nldllqtkel pkgverlvta mnnssslllk iisdildfsk ieseqlkiep
      541 refsprevmn hitanylplv vrkqlglycf iepdvpvsln gdpmrlqqvi snllsnaikf
      601 tdigcivlhv rcdgdylsir vrdtgvgipa kevvrlfdpf fqvgtgvqrn fqgtglglai
      661 ceklismmdg disvdsepgm gsqftlripl ygaqypvkks veglagtccw lavrntslcq
      721 fietslarsg vhtqryegqe paaddilivd dalehtwqgr aavvfcrrhi giplerapge
      781 wvhsvasvhe lpallariys ieldsealss alpttdktad snddmmilvv ddhpinrrll
      841 adqlgslgyq cktandgvda lnvlsknaid ivlsdvnmpn mdgyrltqri rqlgltlpvv
      901 gvtanalaee kqrclesgmd sclskpvtld vlkqtlavya ervrktra