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preprotein translocase; secretion protein of IISP family


LOCUS       NP_459141                901 aa            linear   CON 08-SEP-2022
            [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2].
ACCESSION   NP_459141
VERSION     NP_459141.1
DBLINK      BioProject: PRJNA57799
            BioSample: SAMN02604315
DBSOURCE    REFSEQ: accession NC_003197.2
KEYWORDS    RefSeq.
SOURCE      Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Salmonella.
REFERENCE   1  (residues 1 to 901)
  AUTHORS   McClelland,M., Sanderson,K.E., Spieth,J., Clifton,S.W.,
            Latreille,P., Courtney,L., Porwollik,S., Ali,J., Dante,M., Du,F.,
            Hou,S., Layman,D., Leonard,S., Nguyen,C., Scott,K., Holmes,A.,
            Grewal,N., Mulvaney,E., Ryan,E., Sun,H., Florea,L., Miller,W.,
            Stoneking,T., Nhan,M., Waterston,R. and Wilson,R.K.
  TITLE     Complete genome sequence of Salmonella enterica serovar Typhimurium
            LT2
  JOURNAL   Nature 413 (6858), 852-856 (2001)
   PUBMED   11677609
REFERENCE   2  (residues 1 to 901)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-SEP-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 901)
  AUTHORS   McClelland,M., Jain,A., Saraogi,P., Mendelson,R., Westerman,R.,
            SanMiguel,P. and Csonka,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2016) Department of Microbiology and Molecular
            Genetics, University of California, Irvine, CA 92697, USA
  REMARK    Sequence update by submitter
REFERENCE   4  (residues 1 to 901)
  CONSRTM   The Salmonella typhimurium Genome Sequencing Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-MAR-2001) Genome Sequencing Center, Department of
            Genetics, Washington University School of Medicine, 4444 Forest
            Park Boulevard, St. Louis, MO 63108, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AAL19100.
            Supported by NIH grant 5U 01 AI43283
            
            Coding sequences below are predicted from manually evaluated
            computer analysis, using similarity information and the programs;
            GLIMMER; http://www.tigr.org/softlab/glimmer/glimmer.html and
            GeneMark; http://opal.biology.gatech.edu/GeneMark/
            
            EC numbers were kindly provided by Junko Yabuzaki and the Kyoto
            Encyclopedia of Genes and Genomes; http://www.genome.ad.jp/kegg/,
            and Pedro Romero and Peter Karp at EcoCyc;
            http://ecocyc.PangeaSystems.com/ecocyc/
            
            The analyses of ribosome binding sites and promoter binding sites
            were kindly provided by Heladia Salgado, Julio Collado-Vides and
            ReguonDB;
            http://kinich.cifn.unam.mx:8850/db/regulondb_intro.frameset
            
            This sequence was finished as follows unless otherwise noted: all
            regions were double stranded, sequenced with an alternate
            chemistries or covered by high quality data (i.e., phred quality >=
            30); an attempt was made to resolve all sequencing problems, such
            as compressions and repeats; all regions were covered by sequence
            from more than one m13 subclone.
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..901
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhimurium str. LT2"
                     /strain="LT2"
                     /serovar="Typhimurium"
                     /sub_species="enterica"
                     /culture_collection="ATCC:700720"
                     /culture_collection="SGSC:1412"
                     /type_material="type strain of Salmonella enterica"
                     /db_xref="taxon:99287"
                     /focus
     Protein         1..901
                     /product="preprotein translocase; secretion protein of
                     IISP family"
                     /calculated_mol_wt=101695
     Region          2..901
                     /region_name="SecA"
                     /note="Preprotein translocase subunit SecA (ATPase, RNA
                     helicase) [Intracellular trafficking, secretion, and
                     vesicular transport]; COG0653"
                     /db_xref="CDD:440418"
     CDS             1..901
                     /gene="secA"
                     /locus_tag="STM0136"
                     /coded_by="NC_003197.2:158689..161394"
                     /note="similar to E. coli preprotein translocase;
                     secretion protein (AAC73209.1); Blastp hit to AAC73209.1
                     (901 aa), 95% identity in aa 1 - 900"
                     /transl_table=11
                     /db_xref="GeneID:1251654"
CONTIG      join(WP_000905756.1:1..901)
ORIGIN      
        1 mliklltkvf gsrndrtlrr mrkavslina mepemeklsd delkaktnef rariekgesv
       61 eslipeafav vreaskrvfg mrhfdvqllg gmvlndrcia emrtgegktl tatlpaylna
      121 lsgkgvhvvt vndylaqrda ennrplfefl gmsvginlpg mpapakreay aaditygtnn
      181 eygfdylrdn mafspeervq rklhyalvde vdsilidear tpliisgpae dssemykkvn
      241 kiiphlirqe kedsdtfqge ghfsvdekar qvnlterglv lieellvqeg imdegeslys
      301 pgnimlmhhv taalrahalf trdvdyivkd geviivdeht grtmqgrrws dglhqaveak
      361 egveiqnenq tlasitfqny frlyeklagm tgtadteafe fssiykldtv vvptnrpmir
      421 kdlpdlvymt eaekiqaiie dikertangq pvlvgtisie ksevvsrelt kagikhnvln
      481 akfhaneagi vaqagypaav tiatnmagrg tdimlggswq aevaaleapt eeqiaqikad
      541 wqvrhdavla agglhiigte rhesrridnq lrgrsgrqgd pgssrfylsm edalmrifas
      601 drvsgmmrkl gmkpgeaieh pwvtkaiana qrkvesrnfd irkqlleydd vandqrraiy
      661 tqrnelldvs dvsdtinsir edvfkatida yippqsleem wdipglqerl kndfdlempi
      721 aewldkepel heetlreril aqsievyqrk eevvgaemmr hfekgvmlqt ldslwkehla
      781 amdylrqgih lrgyaqkdpk qeykresfam faamleslky evistlskvq vrmpeeveam
      841 emqrreeaer laqmqqlshq dddaavaadl aaqtgerkig rndpcpcgsg kkykqchgrl
      901 s