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LOCUS NP_416734 875 aa linear CON 09-MAR-2022 ACCESSION NP_416734 VERSION NP_416734.1 DBLINK BioProject: PRJNA57779 BioSample: SAMN02604091 DBSOURCE REFSEQ: accession NC_000913.3 KEYWORDS RefSeq. SOURCE Escherichia coli str. K-12 substr. MG1655 ORGANISM Escherichia coli str. K-12 substr. MG1655 Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia. REFERENCE 1 (residues 1 to 875) AUTHORS Riley,M., Abe,T., Arnaud,M.B., Berlyn,M.K., Blattner,F.R., Chaudhuri,R.R., Glasner,J.D., Horiuchi,T., Keseler,I.M., Kosuge,T., Mori,H., Perna,N.T., Plunkett,G. III, Rudd,K.E., Serres,M.H., Thomas,G.H., Thomson,N.R., Wishart,D. and Wanner,B.L. TITLE Escherichia coli K-12: a cooperatively developed annotation snapshot--2005 JOURNAL Nucleic Acids Res. 34 (1), 1-9 (2006) PUBMED 16397293 REMARK Publication Status: Online-Only REFERENCE 2 (residues 1 to 875) AUTHORS Hayashi,K., Morooka,N., Yamamoto,Y., Fujita,K., Isono,K., Choi,S., Ohtsubo,E., Baba,T., Wanner,B.L., Mori,H. and Horiuchi,T. TITLE Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110 JOURNAL Mol. Syst. Biol. 2, 2006 (2006) PUBMED 16738553 REFERENCE 3 (residues 1 to 875) AUTHORS Blattner,F.R., Plunkett,G. III, Bloch,C.A., Perna,N.T., Burland,V., Riley,M., Collado-Vides,J., Glasner,J.D., Rode,C.K., Mayhew,G.F., Gregor,J., Davis,N.W., Kirkpatrick,H.A., Goeden,M.A., Rose,D.J., Mau,B. and Shao,Y. TITLE The complete genome sequence of Escherichia coli K-12 JOURNAL Science 277 (5331), 1453-1462 (1997) PUBMED 9278503 REFERENCE 4 (residues 1 to 875) AUTHORS Arnaud,M., Berlyn,M.K.B., Blattner,F.R., Galperin,M.Y., Glasner,J.D., Horiuchi,T., Kosuge,T., Mori,H., Perna,N.T., Plunkett,G. III, Riley,M., Rudd,K.E., Serres,M.H., Thomas,G.H. and Wanner,B.L. TITLE Workshop on Annotation of Escherichia coli K-12 JOURNAL Unpublished REMARK Woods Hole, Mass., on 14-18 November 2003 (sequence corrections) REFERENCE 5 (residues 1 to 875) AUTHORS Glasner,J.D., Perna,N.T., Plunkett,G. III, Anderson,B.D., Bockhorst,J., Hu,J.C., Riley,M., Rudd,K.E. and Serres,M.H. TITLE ASAP: Escherichia coli K-12 strain MG1655 version m56 JOURNAL Unpublished REMARK ASAP download 10 June 2004 (annotation updates) REFERENCE 6 (residues 1 to 875) AUTHORS Hayashi,K., Morooka,N., Mori,H. and Horiuchi,T. TITLE A more accurate sequence comparison between genomes of Escherichia coli K12 W3110 and MG1655 strains JOURNAL Unpublished REMARK GenBank accessions AG613214 to AG613378 (sequence corrections) REFERENCE 7 (residues 1 to 875) AUTHORS Perna,N.T. TITLE Escherichia coli K-12 MG1655 yqiK-rfaE intergenic region, genomic sequence correction JOURNAL Unpublished REMARK GenBank accession AY605712 (sequence corrections) REFERENCE 8 (residues 1 to 875) AUTHORS Rudd,K.E. TITLE A manual approach to accurate translation start site annotation: an E. coli K-12 case study JOURNAL Unpublished REFERENCE 9 (residues 1 to 875) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (08-MAR-2022) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 10 (residues 1 to 875) AUTHORS Blattner,F.R. and Plunkett,G. III. TITLE Direct Submission JOURNAL Submitted (30-JUL-2014) Laboratory of Genetics, University of Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA REMARK Protein update by submitter REFERENCE 11 (residues 1 to 875) AUTHORS Blattner,F.R. and Plunkett,G. III. TITLE Direct Submission JOURNAL Submitted (15-NOV-2013) Laboratory of Genetics, University of Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA REMARK Protein update by submitter REFERENCE 12 (residues 1 to 875) AUTHORS Blattner,F.R. and Plunkett,G. III. TITLE Direct Submission JOURNAL Submitted (26-SEP-2013) Laboratory of Genetics, University of Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA REMARK Sequence update by submitter REFERENCE 13 (residues 1 to 875) AUTHORS Rudd,K.E. TITLE Direct Submission JOURNAL Submitted (06-FEB-2013) Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, 118 Gautier Bldg., Miami, FL 33136, USA REMARK Sequence update by submitter REFERENCE 14 (residues 1 to 875) AUTHORS Rudd,K.E. TITLE Direct Submission JOURNAL Submitted (24-APR-2007) Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, 118 Gautier Bldg., Miami, FL 33136, USA REMARK Annotation update from ecogene.org as a multi-database collaboration REFERENCE 15 (residues 1 to 875) AUTHORS Plunkett,G. III. TITLE Direct Submission JOURNAL Submitted (07-FEB-2006) Laboratory of Genetics, University of Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA REMARK Protein updates by submitter REFERENCE 16 (residues 1 to 875) AUTHORS Plunkett,G. III. TITLE Direct Submission JOURNAL Submitted (10-JUN-2004) Laboratory of Genetics, University of Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA REMARK Sequence update by submitter REFERENCE 17 (residues 1 to 875) AUTHORS Plunkett,G. III. TITLE Direct Submission JOURNAL Submitted (13-OCT-1998) Laboratory of Genetics, University of Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA REFERENCE 18 (residues 1 to 875) AUTHORS Blattner,F.R. and Plunkett,G. III. TITLE Direct Submission JOURNAL Submitted (02-SEP-1997) Laboratory of Genetics, University of Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA REFERENCE 19 (residues 1 to 875) AUTHORS Blattner,F.R. and Plunkett,G. III. TITLE Direct Submission JOURNAL Submitted (16-JAN-1997) Laboratory of Genetics, University of Wisconsin, 425G Henry Mall, Madison, WI 53706-1580, USA COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to AAC75291. Changes to proteins and annotation made on March 7, 2022. Current U00096 annotation updates are derived from EcoCyc https://ecocyc.org/. Suggestions for updates can be sent to [email protected]. These updates are being generated from a collaboration that includes EcoCyc, the University of Wisconsin, UniProtKB/Swiss-Prot, and the National Center for Biotechnology Information (NCBI). COMPLETENESS: full length. Method: conceptual translation. FEATURES Location/Qualifiers source 1..875 /organism="Escherichia coli str. K-12 substr. MG1655" /strain="K-12" /sub_strain="MG1655" /db_xref="taxon:511145" Protein 1..875 /product="DNA gyrase subunit A" /EC_number="5.6.2.2" /calculated_mol_wt=96833 Region 7..842 /region_name="PRK05560" /note="DNA gyrase subunit A; Validated" /db_xref="CDD:235502" Region 538..585 /region_name="GyrA_CTD repeat" /note="GyrA_CTD repeat [structural motif]" /db_xref="CDD:293790" Region 588..638 /region_name="GyrA_CTD repeat" /note="GyrA_CTD repeat [structural motif]" /db_xref="CDD:293790" Region 644..688 /region_name="GyrA_CTD repeat" /note="GyrA_CTD repeat [structural motif]" /db_xref="CDD:293790" Region 692..739 /region_name="GyrA_CTD repeat" /note="GyrA_CTD repeat [structural motif]" /db_xref="CDD:293790" Region 742..790 /region_name="GyrA_CTD repeat" /note="GyrA_CTD repeat [structural motif]" /db_xref="CDD:293790" CDS 1..875 /gene="gyrA" /locus_tag="b2231" /gene_synonym="ECK2223; hisW; nalA; nfxA; norA; parD" /coded_by="complement(NC_000913.3:2336793..2339420)" /transl_table=11 /db_xref="UniProtKB/Swiss-Prot:P0AES4" /db_xref="ASAP:ABE-0007370" /db_xref="ECOCYC:EG10423" /db_xref="GeneID:946614" CONTIG join(WP_001281242.1:1..875) ORIGIN 1 msdlareitp vnieeelkss yldyamsviv gralpdvrdg lkpvhrrvly amnvlgndwn 61 kaykksarvv gdvigkyhph gdsavydtiv rmaqpfslry mlvdgqgnfg sidgdsaaam 121 ryteirlaki ahelmadlek etvdfvdnyd gtekipdvmp tkipnllvng ssgiavgmat 181 nipphnltev ingclayidd edisieglme hipgpdfpta aiingrrgie eayrtgrgkv 241 yiraraevev daktgretii vheipyqvnk arliekiael vkekrvegis alrdesdkdg 301 mrivievkrd avgevvlnnl ysqtqlqvsf ginmvalhhg qpkimnlkdi iaafvrhrre 361 vvtrrtifel rkardrahil ealavalani dpiielirha ptpaeaktal vanpwqlgnv 421 aamleragdd aarpewlepe fgvrdglyyl teqqaqaild lrlqkltgle heklldeyke 481 lldqiaellr ilgsadrlme vireelelvr eqfgdkrrte itansadinl edlitqedvv 541 vtlshqgyvk yqplseyeaq rrggkgksaa rikeedfidr llvanthdhi lcfssrgrvy 601 smkvyqlpea trgargrpiv nllpleqder itailpvtef eegvkvfmat angtvkktvl 661 tefnrlrtag kvaiklvdgd eligvdltsg edevmlfsae gkvvrfkess vramgcnttg 721 vrgirlgegd kvvslivprg dgailtatqn gygkrtavae yptksratkg visikvtern 781 glvvgavqvd dcdqimmitd agtlvrtrvs eisivgrntq gvilirtaed envvglqrva 841 epvdeedldt idgsaaegdd eiapevdvdd epeee