MULTISPECIES: DNA topoisomerase (ATP-hydrolyzing) subunit A

LOCUS       WP_001281242             875 aa            linear   BCT 16-DEC-2020
            [Enterobacteriaceae].
ACCESSION   WP_001281242
VERSION     WP_001281242.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01063.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..875
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..875
                     /gene="gyrA"
     Protein         1..875
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit A"
                     /EC_number="5.6.2.2"
                     /GO_component="GO:0009330 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) complex [Evidence
                     IEA]"
                     /GO_function="GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA]"
                     /GO_function="GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /calculated_mol_wt=96833
     Region          7..842
                     /region_name="PRK05560"
                     /note="DNA gyrase subunit A; Validated"
                     /db_xref="CDD:235502"
     Region          538..585
                     /region_name="GyrA_CTD repeat"
                     /note="GyrA_CTD repeat [structural motif]"
                     /db_xref="CDD:293790"
     Region          588..638
                     /region_name="GyrA_CTD repeat"
                     /note="GyrA_CTD repeat [structural motif]"
                     /db_xref="CDD:293790"
     Region          644..688
                     /region_name="GyrA_CTD repeat"
                     /note="GyrA_CTD repeat [structural motif]"
                     /db_xref="CDD:293790"
     Region          692..739
                     /region_name="GyrA_CTD repeat"
                     /note="GyrA_CTD repeat [structural motif]"
                     /db_xref="CDD:293790"
     Region          742..790
                     /region_name="GyrA_CTD repeat"
                     /note="GyrA_CTD repeat [structural motif]"
                     /db_xref="CDD:293790"
ORIGIN      
        1 msdlareitp vnieeelkss yldyamsviv gralpdvrdg lkpvhrrvly amnvlgndwn
       61 kaykksarvv gdvigkyhph gdsavydtiv rmaqpfslry mlvdgqgnfg sidgdsaaam
      121 ryteirlaki ahelmadlek etvdfvdnyd gtekipdvmp tkipnllvng ssgiavgmat
      181 nipphnltev ingclayidd edisieglme hipgpdfpta aiingrrgie eayrtgrgkv
      241 yiraraevev daktgretii vheipyqvnk arliekiael vkekrvegis alrdesdkdg
      301 mrivievkrd avgevvlnnl ysqtqlqvsf ginmvalhhg qpkimnlkdi iaafvrhrre
      361 vvtrrtifel rkardrahil ealavalani dpiielirha ptpaeaktal vanpwqlgnv
      421 aamleragdd aarpewlepe fgvrdglyyl teqqaqaild lrlqkltgle heklldeyke
      481 lldqiaellr ilgsadrlme vireelelvr eqfgdkrrte itansadinl edlitqedvv
      541 vtlshqgyvk yqplseyeaq rrggkgksaa rikeedfidr llvanthdhi lcfssrgrvy
      601 smkvyqlpea trgargrpiv nllpleqder itailpvtef eegvkvfmat angtvkktvl
      661 tefnrlrtag kvaiklvdgd eligvdltsg edevmlfsae gkvvrfkess vramgcnttg
      721 vrgirlgegd kvvslivprg dgailtatqn gygkrtavae yptksratkg visikvtern
      781 glvvgavqvd dcdqimmitd agtlvrtrvs eisivgrntq gvilirtaed envvglqrva
      841 epvdeedldt idgsaaegdd eiapevdvdd epeee