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alpha-2-macroglobulin family protein [Escherichia coli O157:H7 str.


LOCUS       NP_311138               1464 aa            linear   CON 12-FEB-2021
            Sakai].
ACCESSION   NP_311138
VERSION     NP_311138.2
DBLINK      BioProject: PRJNA226
            BioSample: SAMN01911278
DBSOURCE    REFSEQ: accession NC_002695.2
KEYWORDS    RefSeq.
SOURCE      Escherichia coli O157:H7 str. Sakai
  ORGANISM  Escherichia coli O157:H7 str. Sakai
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1
  AUTHORS   Hayashi,T., Makino,K., Ohnishi,M., Kurokawa,K., Ishii,K.,
            Yokoyama,K., Han,C.G., Ohtsubo,E., Nakayama,K., Murata,T.,
            Tanaka,M., Tobe,T., Iida,T., Takami,H., Honda,T., Sasakawa,C.,
            Ogasawara,N., Yasunaga,T., Kuhara,S., Shiba,T., Hattori,M. and
            Shinagawa,H.
  TITLE     Complete genome sequence of enterohemorrhagic Escherichia coli
            O157:H7 and genomic comparison with a laboratory strain K-12
  JOURNAL   DNA Res. 8 (1), 11-22 (2001)
   PUBMED   11258796
  REMARK    Erratum:[DNA Res 2001 Apr 27;8(2):96]
REFERENCE   2
  AUTHORS   Yokoyama,K., Makino,K., Kubota,Y., Watanabe,M., Kimura,S.,
            Yutsudo,C.H., Kurokawa,K., Ishii,K., Hattori,M., Tatsuno,I.,
            Abe,H., Yoh,M., Iida,T., Ohnishi,M., Hayashi,T., Yasunaga,T.,
            Honda,T., Sasakawa,C. and Shinagawa,H.
  TITLE     Complete nucleotide sequence of the prophage VT1-Sakai carrying the
            Shiga toxin 1 genes of the enterohemorrhagic Escherichia coli
            O157:H7 strain derived from the Sakai outbreak
  JOURNAL   Gene 258 (1-2), 127-139 (2000)
   PUBMED   11111050
REFERENCE   3
  AUTHORS   Ohnishi,M., Murata,T., Nakayama,K., Kuhara,S., Hattori,M.,
            Kurokawa,K., Yasunaga,T., Yokoyama,K., Makino,K., Shinagawa,H. and
            Hayashi,T.
  TITLE     Comparative analysis of the whole set of rRNA operons between an
            enterohemorrhagic Escherichia coli O157:H7 Sakai strain and an
            Escherichia coli K-12 strain MG1655
  JOURNAL   Syst. Appl. Microbiol. 23 (3), 315-324 (2000)
   PUBMED   11108008
REFERENCE   4
  AUTHORS   Makino,K., Yokoyama,K., Kubota,Y., Yutsudo,C.H., Kimura,S.,
            Kurokawa,K., Ishii,K., Hattori,M., Tatsuno,I., Abe,H., Iida,T.,
            Yamamoto,K., Onishi,M., Hayashi,T., Yasunaga,T., Honda,T.,
            Sasakawa,C. and Shinagawa,H.
  TITLE     Complete nucleotide sequence of the prophage VT2-Sakai carrying the
            verotoxin 2 genes of the enterohemorrhagic Escherichia coli O157:H7
            derived from the Sakai outbreak
  JOURNAL   Genes Genet. Syst. 74 (5), 227-239 (1999)
   PUBMED   10734605
REFERENCE   5  (residues 1 to 1464)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-AUG-2018) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   6  (residues 1 to 1464)
  AUTHORS   Ogura,Y., Kurokawa,K., Hayashi,T. and Hattori,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUN-2000) Contact:Yoshitoshi Ogura Kyushu University;
            31-1 Maidashi Higashi-ku, Fukuoka, Fukuoka 812-8582, Japan
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to BAB36534.
            
            On Aug 15, 2018 this sequence version replaced NP_311138.1.
            On May 10, 2018 this sequence version replased gi: 47118301
            
            This update is obtained as follows: the Sakai genome was
            resequenced by illumina MiSeq and PacBio RS II sequencers and 78
            sites of single base error, 11 sites of insertion (10 one-base
            insertions and a 141-base insertion) and 16 sites of deletion (14
            one-base deletions, a three-base deletion and a six-base deletion)
            were corrected. Annotation was performed using DFAST
            auto-annotation system with manual curation.
            
            This work was done in collaboration with Tetsuya Hayashi, Makoto
            Ohnishi, Keisuke Nakayama (Miyazaki Medical College), Kozo Makino,
            Ken Kurokawa, Katsushi Yokoyama, Masashi Tanaka, Takeshi Honda,
            Teruo Yasunaga, Hideo Shinagawa (Osaka University), Takahiro Murata
            (Shinshu University), Chang-Gyun Han, Eiichi Ohtsubo, Toru Tobe,
            Chihiro Sasakawa (University of Tokyo), Hideto Takami (Japan Marine
            Science and Technology Center), Naotake Ogasawara (Nara Institute
            of Science and Technology), Satoru Kuhara (Kuyshu University), and
            supported by the Research for the Future Program of the Japan
            Society for the Promotion of Science.
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..1464
                     /organism="Escherichia coli O157:H7 str. Sakai"
                     /strain="Sakai"
                     /sub_strain="RIMD 0509952"
                     /serovar="O157:H7"
                     /db_xref="taxon:386585"
     Protein         1..1464
                     /product="alpha-2-macroglobulin family protein"
                     /calculated_mol_wt=162377
     Region          152..1456
                     /region_name="YfaS"
                     /note="Uncharacterized conserved protein YfaS,
                     alpha-2-macroglobulin family [General function prediction
                     only]; COG2373"
                     /db_xref="CDD:441940"
     CDS             1..1464
                     /gene="yfaS"
                     /locus_tag="ECs_3111"
                     /coded_by="complement(NC_002695.2:3055704..3060098)"
                     /transl_table=11
                     /db_xref="GeneID:916819"
CONTIG      join(WP_021502145.1:1..1464)
ORIGIN      
        1 mrleapgrdy rryqmeeygg vdvrlyripd pmaflrqqkn lhrivvqpqy lgdglnntlt
       61 wlwdnwygks rrvmqrtfss qsrqnvtqal pelqlgnaii kpsryvqnnq fsplkkyplv
      121 eqfryplwqa kpvepqqgvk legassnfis pqpgniyipl gqqepglylv eamvggyrat
      181 tvvfvsdtva lskvsgkell vwtagkkqge akpgseilwt dglgvmtrgv tddsgtlqlq
      241 hispersyil gkdaeggvfv senffyesei yntrlyiftd rplyragdrv dvkvmgrefh
      301 dplhsspivs apaklsvlda ngsllqtvdv tldarnggqg sfrlpenava ggyelrlayr
      361 nqvysssfrv anyikphfei glaldkkefk tgeavsgklq llypdgepvk narvqlslra
      421 qqlsmvgndl ryagrfpvsl egsetvsdas ghvalnlpaa dkpsrylltv sasdgaayrv
      481 tttkeilier glahyslsta aqysnsgesv vfryaaless kqvpvtyewl rledrtshsg
      541 dlpsggksft vnfdkpgnyn ltlrdkdgli laglshavsg kgsmshtgtv divadktlyq
      601 pgetakmlit fpepideall tlerdrveqq sllshpanwl tlqrlndtqy earvpvsnsf
      661 apnitfsvly trngqysfqn agikvavpql dirvktdkth yqpgelvnve ltsslkgkpv
      721 saqltvgvvd emiyalqpei apnigkffyp lgrnnvrtss slsfisydqa lssepvapga
      781 tnrserrvkm lerprreevd taawmpsltt dkqgkayftf lmpdsltrwr itargmngdg
      841 lvgqgraylr seknlymkws mptvyrvgdk psaglfifsq qdnepvalvt kfagaemrqt
      901 ltlhkganyi slaqniqqsg llsaelqqng qvqdsistkl sfvdnswpve qqknvmlggg
      961 dnalmlpeqa snirlqsset pqeifrnnld alvdepwggv intgsrlipl slawrsladh
     1021 qsaaandirq miqdnrlrlm qlagpgarft wwgedgngda fltawawyad wqasqalgvt
     1081 qqpeywqhml dsyaeqadnm pllhralvla waqemnlpck tllkgldeai arrgtktedf
     1141 seedtrdind slildtpesp ladavanvlt mtllkkaqlk stvmpqvqqy awdkavnsnq
     1201 plahtvvlln sggdatqaaa ilsgltaeqs tieralamnw lakymatmps vvlpapagaw
     1261 akhkltggge ywrwvgqgvp dilsfgdels pqnvqvrwre aaktaqqsni pvtverqlyr
     1321 lipgeeemsf tlqpvtsnei dsdalyldei tltseqdavl rygqvevplp pgadverttw
     1381 gisvnkpnag kqqgqlleka rnemgelaym vpvkeltgtv tfrhllrfsq kgqfvlppar
     1441 yvrsyapaqq svaagsewtg mqvk