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LOCUS NP_253179 1516 aa linear CON 24-JAN-2019 ACCESSION NP_253179 VERSION NP_253179.1 DBLINK BioProject: PRJNA57945 Assembly: GCF_000006765.1 DBSOURCE REFSEQ: accession NC_002516.2 KEYWORDS RefSeq. SOURCE Pseudomonas aeruginosa PAO1 ORGANISM Pseudomonas aeruginosa PAO1 Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas. REFERENCE 1 (residues 1 to 1516) AUTHORS Winsor,G.L., Van Rossum,T., Lo,R., Khaira,B., Whiteside,M.D., Hancock,R.E. and Brinkman,F.S. TITLE Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes JOURNAL Nucleic acids Res. 37 (DATABASE ISSUE), D483-D488 (2009) PUBMED 18978025 REFERENCE 2 (residues 1 to 1516) AUTHORS Cirz,R.T., O'Neill,B.M., Hammond,J.A., Head,S.R. and Romesberg,F.E. TITLE Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin JOURNAL J. Bacteriol. 188 (20), 7101-7110 (2006) PUBMED 17015649 REFERENCE 3 (residues 1 to 1516) AUTHORS Palmer,K.L., Mashburn,L.M., Singh,P.K. and Whiteley,M. TITLE Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology JOURNAL J. Bacteriol. 187 (15), 5267-5277 (2005) PUBMED 16030221 REFERENCE 4 (residues 1 to 1516) AUTHORS Salunkhe,P., Smart,C.H., Morgan,J.A., Panagea,S., Walshaw,M.J., Hart,C.A., Geffers,R., Tummler,B. and Winstanley,C. TITLE A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance JOURNAL J. Bacteriol. 187 (14), 4908-4920 (2005) PUBMED 15995206 REFERENCE 5 (residues 1 to 1516) AUTHORS Filiatrault,M.J., Wagner,V.E., Bushnell,D., Haidaris,C.G., Iglewski,B.H. and Passador,L. TITLE Effect of anaerobiosis and nitrate on gene expression in Pseudomonas aeruginosa JOURNAL Infect. Immun. 73 (6), 3764-3772 (2005) PUBMED 15908409 REFERENCE 6 (residues 1 to 1516) AUTHORS Rasmussen,T.B., Bjarnsholt,T., Skindersoe,M.E., Hentzer,M., Kristoffersen,P., Kote,M., Nielsen,J., Eberl,L. and Givskov,M. TITLE Screening for quorum-sensing inhibitors (QSI) by use of a novel genetic system, the QSI selector JOURNAL J. Bacteriol. 187 (5), 1799-1814 (2005) PUBMED 15716452 REFERENCE 7 (residues 1 to 1516) AUTHORS Winsor,G.L., Lo,R., Sui,S.J., Ung,K.S., Huang,S., Cheng,D., Ching,W.K., Hancock,R.E. and Brinkman,F.S. TITLE Pseudomonas aeruginosa Genome Database and PseudoCap: facilitating community-based, continually updated, genome annotation JOURNAL Nucleic acids Res. 33 (DATABASE ISSUE), D338-D343 (2005) PUBMED 15608211 REFERENCE 8 (residues 1 to 1516) AUTHORS Wagner,V.E., Bushnell,D., Passador,L., Brooks,A.I. and Iglewski,B.H. TITLE Microarray analysis of Pseudomonas aeruginosa quorum-sensing regulons: effects of growth phase and environment JOURNAL J. Bacteriol. 185 (7), 2080-2095 (2003) PUBMED 12644477 REFERENCE 9 (residues 1 to 1516) AUTHORS Schuster,M., Lostroh,C.P., Ogi,T. and Greenberg,E.P. TITLE Identification, timing, and signal specificity of Pseudomonas aeruginosa quorum-controlled genes: a transcriptome analysis JOURNAL J. Bacteriol. 185 (7), 2066-2079 (2003) PUBMED 12644476 REFERENCE 10 (residues 1 to 1516) AUTHORS Stover,C.K., Pham,X.Q., Erwin,A.L., Mizoguchi,S.D., Warrener,P., Hickey,M.J., Brinkman,F.S., Hufnagle,W.O., Kowalik,D.J., Lagrou,M., Garber,R.L., Goltry,L., Tolentino,E., Westbrock-Wadman,S., Yuan,Y., Brody,L.L., Coulter,S.N., Folger,K.R., Kas,A., Larbig,K., Lim,R., Smith,K., Spencer,D., Wong,G.K., Wu,Z., Paulsen,I.T., Reizer,J., Saier,M.H., Hancock,R.E., Lory,S. and Olson,M.V. TITLE Complete genome sequence of Pseudomonas aeruginosa PA01, an opportunistic pathogen JOURNAL Nature 406 (6799), 959-964 (2000) PUBMED 10984043 REFERENCE 11 (residues 1 to 1516) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (06-OCT-2010) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 12 (residues 1 to 1516) AUTHORS Winsor,G.L., Hancock,R.E. and Brinkman,F.S. CONSRTM Pseudomonas aeruginosa Community Annotation Project (PseudoCap) TITLE Direct Submission JOURNAL Submitted (08-SEP-2010) Department of Molecular Biology and Biochemisry, Simon Fraser University, 8888 University Dr., Burnaby, British Columbia V5A 1S6, Canada REMARK protein update by submitter REFERENCE 13 (residues 1 to 1516) AUTHORS Winsor,G.L., Hancock,R.E. and Brinkman,F.S. CONSRTM Pseudomonas aeruginosa Community Annotation Project (PseudoCap) TITLE Direct Submission JOURNAL Submitted (02-OCT-2008) Department of Molecular Biology and Biochemisry, Simon Fraser University, 8888 University Dr., Burnaby, British Columbia V5A 1S6, Canada REMARK protein update by submitter REFERENCE 14 (residues 1 to 1516) AUTHORS Winsor,G.L., Hancock,R.E. and Brinkman,F.S. CONSRTM Pseudomonas aeruginosa Community Annotation Project (PseudoCap) TITLE Direct Submission JOURNAL Submitted (05-JUL-2006) Department of Molecular Biology and Biochemisry, Simon Fraser University, 8888 University Dr., Burnaby, British Columbia V5A 1S6, Canada REMARK Sequence update by submitter REFERENCE 15 (residues 1 to 1516) AUTHORS Ung,K.S., Hancock,R.E. and Brinkman,F.S. CONSRTM Pseudomonas aeruginosa Community Annotation Project (PseudoCap) TITLE Direct Submission JOURNAL Submitted (04-FEB-2003) Department of Molecular Biology and Biochemistry, Simon Fraser University, 8888 University Dr., Burnaby, British Columbia V5A 1S6, Canada REFERENCE 16 (residues 1 to 1516) AUTHORS Stover,C.K., Pham,X.-Q.T., Erwin,A.L., Mizoguchi,S.D., Warrener,P., Hickey,M.J., Brinkman,F.S.L., Hufnagle,W.O., Kowalik,D.J., Lagrou,M., Garber,R.L., Goltry,L., Tolentino,E., Westbrock-Wadman,S., Yuan,Y., Brody,L.L., Coulter,S.N., Folger,K.R., Kas,A., Larbig,K., Lim,R.M., Smith,K.A., Spencer,D.H., Wong,G.K.-S., Wu,Z., Paulsen,I.T., Reizer,J., Saier,M.H., Hancock,R.E.W., Lory,S. and Olson,M.V. CONSRTM Pseudomonas aeruginosa Community Annotation Project (PseudoCap) TITLE Direct Submission JOURNAL Submitted (16-MAY-2000) Department of Medicine and Genetics, University of Washington Genome Center, University Of Washington, Box 352145, Seattle, WA 98195, USA COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to AAG07877. Method: conceptual translation. FEATURES Location/Qualifiers source 1..1516 /organism="Pseudomonas aeruginosa PAO1" /strain="PAO1" /db_xref="taxon:208964" Protein 1..1516 /product="hypothetical protein" /calculated_mol_wt=167299 Region 4..1506 /region_name="YfaS" /note="Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family [General function prediction only]; COG2373" /db_xref="CDD:441940" CDS 1..1516 /locus_tag="PA4489" /coded_by="complement(NC_002516.2:5020402..5024952)" /note="'Product name confidence: class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences)'" /transl_table=11 /db_xref="GeneID:881072" CONTIG join(WP_003112866.1:1..1516) ORIGIN 1 msnlrrfsrs lavaalvllp faavqaedtv epsgytpmag esfflladss fatdeearvr 61 leapgrdyrr yrmepyggvd vrlyrieqpl eflkrqknlh rvlaegqfkg eglsntlayl 121 wdnwyrksrr vmqrafsyes rqqvteavpe lkmgnamtap tpydaqpqya pipglplvsq 181 fryplwdakp ieppqdvkla gsssefinvv pgnvyiplgk lkpglylvea lvgkyrattv 241 vfvsnsvavs kvagdellvw tarkhegtpv pdtkvlwtdg lgvmssgntd adgllrlkha 301 spersyvige dreggvfvse nfyydseiyd tkiyaftdrp lyrpgdwvsl kmvgrefkda 361 rqsqaaasap vrlsvidasg tvlqsldlrf daksgangrf qlpenavagg yelrfdyrgq 421 tyssafrvae yikphfeval dlakpdfkta epvkgeivll ypdgkpvana rlqlslraqq 481 lsmvdnelqy lgqfpvelss telttdgkgr aaielppaek psrymltifa sdgaayrvkt 541 skeilierga aryrlsapqr fsaagekvef syaseqptpl kpssyqwirl edratdsgpv 601 adgrfaltfe rpgtysvelr ddkgqllgat ghsvsgegvk svpgtvevvf dkpeyrtgee 661 asalitfpep vedallsler dkveatalls kgadwlrlek lnptqyrvwi pvreefspnl 721 tfsvlytkgg dysfqnagik vgmpqveidi atdkeryepg etvtvtlatr fagkpvsshl 781 tvsvvdemvy alqaeiapgi dqffyhprrn nvrtsaslaf isydvalpgs tsapgranrs 841 ergvkvlerp rredvdtaaw qpelvtdaqg kasfsfrmpd sltrwritar aiddngqvgq 901 kkqflrsekp lylkwsgptr frqgdqpdlg lfvfnqgeqp vkaellsgpp gsqrsqtlel 961 akgvnyipla qqplsdgdws aelrqdgqvr drlavrfnll adgwqveqmq nlslaaasnp 1021 lqlpadardv rlrladgpaa aylgnlddll eypyggveqt asqllplsia ypalaggepr 1081 irdrlrlimq nsrlrlvqma gpdawfawwg gdvdgdaflt ayayyadwya sraleiqlpa 1141 ehwqrilepy akqatqtpll qralilafar dmqlpvntll ggllndlana gegqaraepl 1201 eaddglvlgd pdsavglaaa rvlavdlarq lrvavpapla aqaetatqrl reaglpftda 1261 llasrsavdg qqasallqrl apaqstlera laltwlqgal aqapqgklpq ppkdwqaqrg 1321 asgetywqwr grgipswvdl deaparplpv alsyrsaqap sgqlpvqisr rllrlvpgeg 1381 afefkveevg dkplssdely ldevtlnvpe dtalrygmle lplppgadve rttwgikisg 1441 lagdeattle rarnepgelf ygvpvdslsg eqrfrhlvrf sqkgsfnlpp arylrlyape 1501 qqaleakpal akvkve