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LOCUS NP_252801 1417 aa linear CON 24-JAN-2019 PAO1]. ACCESSION NP_252801 VERSION NP_252801.1 DBLINK BioProject: PRJNA57945 Assembly: GCF_000006765.1 DBSOURCE REFSEQ: accession NC_002516.2 KEYWORDS RefSeq. SOURCE Pseudomonas aeruginosa PAO1 ORGANISM Pseudomonas aeruginosa PAO1 Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas. REFERENCE 1 (residues 1 to 1417) AUTHORS Winsor,G.L., Van Rossum,T., Lo,R., Khaira,B., Whiteside,M.D., Hancock,R.E. and Brinkman,F.S. TITLE Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes JOURNAL Nucleic acids Res. 37 (DATABASE ISSUE), D483-D488 (2009) PUBMED 18978025 REFERENCE 2 (residues 1 to 1417) AUTHORS Cirz,R.T., O'Neill,B.M., Hammond,J.A., Head,S.R. and Romesberg,F.E. TITLE Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin JOURNAL J. Bacteriol. 188 (20), 7101-7110 (2006) PUBMED 17015649 REFERENCE 3 (residues 1 to 1417) AUTHORS Palmer,K.L., Mashburn,L.M., Singh,P.K. and Whiteley,M. TITLE Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology JOURNAL J. Bacteriol. 187 (15), 5267-5277 (2005) PUBMED 16030221 REFERENCE 4 (residues 1 to 1417) AUTHORS Salunkhe,P., Smart,C.H., Morgan,J.A., Panagea,S., Walshaw,M.J., Hart,C.A., Geffers,R., Tummler,B. and Winstanley,C. TITLE A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance JOURNAL J. Bacteriol. 187 (14), 4908-4920 (2005) PUBMED 15995206 REFERENCE 5 (residues 1 to 1417) AUTHORS Filiatrault,M.J., Wagner,V.E., Bushnell,D., Haidaris,C.G., Iglewski,B.H. and Passador,L. TITLE Effect of anaerobiosis and nitrate on gene expression in Pseudomonas aeruginosa JOURNAL Infect. Immun. 73 (6), 3764-3772 (2005) PUBMED 15908409 REFERENCE 6 (residues 1 to 1417) AUTHORS Rasmussen,T.B., Bjarnsholt,T., Skindersoe,M.E., Hentzer,M., Kristoffersen,P., Kote,M., Nielsen,J., Eberl,L. and Givskov,M. TITLE Screening for quorum-sensing inhibitors (QSI) by use of a novel genetic system, the QSI selector JOURNAL J. Bacteriol. 187 (5), 1799-1814 (2005) PUBMED 15716452 REFERENCE 7 (residues 1 to 1417) AUTHORS Winsor,G.L., Lo,R., Sui,S.J., Ung,K.S., Huang,S., Cheng,D., Ching,W.K., Hancock,R.E. and Brinkman,F.S. TITLE Pseudomonas aeruginosa Genome Database and PseudoCap: facilitating community-based, continually updated, genome annotation JOURNAL Nucleic acids Res. 33 (DATABASE ISSUE), D338-D343 (2005) PUBMED 15608211 REFERENCE 8 (residues 1 to 1417) AUTHORS Wagner,V.E., Bushnell,D., Passador,L., Brooks,A.I. and Iglewski,B.H. TITLE Microarray analysis of Pseudomonas aeruginosa quorum-sensing regulons: effects of growth phase and environment JOURNAL J. Bacteriol. 185 (7), 2080-2095 (2003) PUBMED 12644477 REFERENCE 9 (residues 1 to 1417) AUTHORS Schuster,M., Lostroh,C.P., Ogi,T. and Greenberg,E.P. TITLE Identification, timing, and signal specificity of Pseudomonas aeruginosa quorum-controlled genes: a transcriptome analysis JOURNAL J. Bacteriol. 185 (7), 2066-2079 (2003) PUBMED 12644476 REFERENCE 10 (residues 1 to 1417) AUTHORS Stover,C.K., Pham,X.Q., Erwin,A.L., Mizoguchi,S.D., Warrener,P., Hickey,M.J., Brinkman,F.S., Hufnagle,W.O., Kowalik,D.J., Lagrou,M., Garber,R.L., Goltry,L., Tolentino,E., Westbrock-Wadman,S., Yuan,Y., Brody,L.L., Coulter,S.N., Folger,K.R., Kas,A., Larbig,K., Lim,R., Smith,K., Spencer,D., Wong,G.K., Wu,Z., Paulsen,I.T., Reizer,J., Saier,M.H., Hancock,R.E., Lory,S. and Olson,M.V. TITLE Complete genome sequence of Pseudomonas aeruginosa PA01, an opportunistic pathogen JOURNAL Nature 406 (6799), 959-964 (2000) PUBMED 10984043 REFERENCE 11 (residues 1 to 1417) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (06-OCT-2010) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 12 (residues 1 to 1417) AUTHORS Winsor,G.L., Hancock,R.E. and Brinkman,F.S. CONSRTM Pseudomonas aeruginosa Community Annotation Project (PseudoCap) TITLE Direct Submission JOURNAL Submitted (08-SEP-2010) Department of Molecular Biology and Biochemisry, Simon Fraser University, 8888 University Dr., Burnaby, British Columbia V5A 1S6, Canada REMARK protein update by submitter REFERENCE 13 (residues 1 to 1417) AUTHORS Winsor,G.L., Hancock,R.E. and Brinkman,F.S. CONSRTM Pseudomonas aeruginosa Community Annotation Project (PseudoCap) TITLE Direct Submission JOURNAL Submitted (02-OCT-2008) Department of Molecular Biology and Biochemisry, Simon Fraser University, 8888 University Dr., Burnaby, British Columbia V5A 1S6, Canada REMARK protein update by submitter REFERENCE 14 (residues 1 to 1417) AUTHORS Winsor,G.L., Hancock,R.E. and Brinkman,F.S. CONSRTM Pseudomonas aeruginosa Community Annotation Project (PseudoCap) TITLE Direct Submission JOURNAL Submitted (05-JUL-2006) Department of Molecular Biology and Biochemisry, Simon Fraser University, 8888 University Dr., Burnaby, British Columbia V5A 1S6, Canada REMARK Sequence update by submitter REFERENCE 15 (residues 1 to 1417) AUTHORS Ung,K.S., Hancock,R.E. and Brinkman,F.S. CONSRTM Pseudomonas aeruginosa Community Annotation Project (PseudoCap) TITLE Direct Submission JOURNAL Submitted (04-FEB-2003) Department of Molecular Biology and Biochemistry, Simon Fraser University, 8888 University Dr., Burnaby, British Columbia V5A 1S6, Canada REFERENCE 16 (residues 1 to 1417) AUTHORS Stover,C.K., Pham,X.-Q.T., Erwin,A.L., Mizoguchi,S.D., Warrener,P., Hickey,M.J., Brinkman,F.S.L., Hufnagle,W.O., Kowalik,D.J., Lagrou,M., Garber,R.L., Goltry,L., Tolentino,E., Westbrock-Wadman,S., Yuan,Y., Brody,L.L., Coulter,S.N., Folger,K.R., Kas,A., Larbig,K., Lim,R.M., Smith,K.A., Spencer,D.H., Wong,G.K.-S., Wu,Z., Paulsen,I.T., Reizer,J., Saier,M.H., Hancock,R.E.W., Lory,S. and Olson,M.V. CONSRTM Pseudomonas aeruginosa Community Annotation Project (PseudoCap) TITLE Direct Submission JOURNAL Submitted (16-MAY-2000) Department of Medicine and Genetics, University of Washington Genome Center, University Of Washington, Box 352145, Seattle, WA 98195, USA COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to AAG07499. Method: conceptual translation. FEATURES Location/Qualifiers source 1..1417 /organism="Pseudomonas aeruginosa PAO1" /strain="PAO1" /db_xref="taxon:208964" Protein 1..1417 /product="sensor/response regulator hybrid protein" /calculated_mol_wt=153764 Region 36..587 /region_name="CHASE1" /note="Extracytoplasmic sensor domain CHASE1 (specificity unknown) [Signal transduction mechanisms]; COG3614" /db_xref="CDD:442832" Region 480..751 /region_name="PAS" /note="PAS domain [Signal transduction mechanisms]; COG2202" /db_xref="CDD:441804" Region <771..1379 /region_name="PRK11107" /note="hybrid sensory histidine kinase BarA; Provisional" /db_xref="CDD:236848" CDS 1..1417 /locus_tag="PA4112" /coded_by="complement(NC_002516.2:4595849..4600102)" /note="'Product name confidence: class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene)'" /transl_table=11 /db_xref="GeneID:877889" CONTIG join(WP_003113014.1:1..1417) ORIGIN 1 mnvqqskfrl srwagatlal glllsglgaw glalvneqqa rmalereael laeavtrrve 61 lyqyglrgvr galltagevh idrelfrrys ltrdidrefp gargfgfirr vaaadeagfl 121 rqaradgqpe friqqltphd geryviqyie pvarngqalg ldiaseanrr eaaraaletg 181 qvrltgpitl vqasglrqqs flilmpiyrs gitpppgpqr elegfgwsya plltgevlag 241 lpidnaaihl elsdvtgdga avpffvngaa apaqrlfghm lrreiygrhw qmafsalplf 301 vqrlhqpspr ilflagslvs lllaalvnas algrlrrrre aatqarlaai vgnsadgiig 361 vgldgvisdw nrgaealfgy reeqavgrrv vdllvppske neeldilari arkeqvvsfd 421 tvrrhqdghl ldvavtvspi lgpdggvvga sktvrdisak kaaearirel ntglehqiae 481 rtaelrrlnv llgsvlqaas evsiitldrd giisgfnlga ermlgyrade vvgkasptll 541 hserellarg qelgeegfrv lvaraeqega etrewtylrk dgsplsvtls vtvlrdeaga 601 ingylgiavd vtewrnaere maaardqlqm aadvarlgiw rwnladdslq wnermcemyg 661 qplalrdggl vyehwrsrlh pedlerteas lraavegrgn ydvifrvvlp dggirfiqag 721 aqverdadgn plqvtginid itsdqqlqar lreakeqada asaakssfla nmsheirtpm 781 navlgmlqla rqtdlnerqr dyldkassaa tsllgllndi ldyskieagk lvlemlpfel 841 eplmqdlavv lsgnqgdkdv evifdidpel psavvgdrlr lqqilinlag nalkftargh 901 vlvslrrlah dahlvrlrvl vadtgigisa eqqqrifegf tqaeastsrr fggtglglfi 961 ckrlvdlmgg elrvesapgs gsrfwfdldl dvahdqplra acpgageplr llvaddnlva 1021 gellertvga lgwradcvgs gseavarvqa amaegrrydv vlmdwrmpdl dglsaaqlir 1081 qlqgdlpppm vimitaygre vladardhsa ppfvdfltkp vtpkqladsv lhalhgeqga 1141 panppprpve rtqrlrgvrl lvvednalnr qvaaellsse garvaladgg lagvqqvlea 1201 svpfdavlmd mqmpdidgle atrriradgr faglpilamt anasladrea claagmndhv 1261 akpidkerlv lcllghlgrs gargapataa dagelvearg divgrfggsl elivqvlrrf 1321 vpdmqdlfaq lerqlgegdv qgsaatlhti kgsastvgas alagrasele qalrradplr 1381 gmeilagirl delrtlcdac llrlqamfgd vqaesas