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LOCUS NP_252417 1746 aa linear CON 24-JAN-2019 ACCESSION NP_252417 VERSION NP_252417.1 DBLINK BioProject: PRJNA57945 Assembly: GCF_000006765.1 DBSOURCE REFSEQ: accession NC_002516.2 KEYWORDS RefSeq. SOURCE Pseudomonas aeruginosa PAO1 ORGANISM Pseudomonas aeruginosa PAO1 Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas. REFERENCE 1 (residues 1 to 1746) AUTHORS Winsor,G.L., Van Rossum,T., Lo,R., Khaira,B., Whiteside,M.D., Hancock,R.E. and Brinkman,F.S. TITLE Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes JOURNAL Nucleic acids Res. 37 (DATABASE ISSUE), D483-D488 (2009) PUBMED 18978025 REFERENCE 2 (residues 1 to 1746) AUTHORS Cirz,R.T., O'Neill,B.M., Hammond,J.A., Head,S.R. and Romesberg,F.E. TITLE Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin JOURNAL J. Bacteriol. 188 (20), 7101-7110 (2006) PUBMED 17015649 REFERENCE 3 (residues 1 to 1746) AUTHORS Palmer,K.L., Mashburn,L.M., Singh,P.K. and Whiteley,M. TITLE Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology JOURNAL J. Bacteriol. 187 (15), 5267-5277 (2005) PUBMED 16030221 REFERENCE 4 (residues 1 to 1746) AUTHORS Salunkhe,P., Smart,C.H., Morgan,J.A., Panagea,S., Walshaw,M.J., Hart,C.A., Geffers,R., Tummler,B. and Winstanley,C. TITLE A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance JOURNAL J. Bacteriol. 187 (14), 4908-4920 (2005) PUBMED 15995206 REFERENCE 5 (residues 1 to 1746) AUTHORS Filiatrault,M.J., Wagner,V.E., Bushnell,D., Haidaris,C.G., Iglewski,B.H. and Passador,L. TITLE Effect of anaerobiosis and nitrate on gene expression in Pseudomonas aeruginosa JOURNAL Infect. Immun. 73 (6), 3764-3772 (2005) PUBMED 15908409 REFERENCE 6 (residues 1 to 1746) AUTHORS Rasmussen,T.B., Bjarnsholt,T., Skindersoe,M.E., Hentzer,M., Kristoffersen,P., Kote,M., Nielsen,J., Eberl,L. and Givskov,M. TITLE Screening for quorum-sensing inhibitors (QSI) by use of a novel genetic system, the QSI selector JOURNAL J. Bacteriol. 187 (5), 1799-1814 (2005) PUBMED 15716452 REFERENCE 7 (residues 1 to 1746) AUTHORS Winsor,G.L., Lo,R., Sui,S.J., Ung,K.S., Huang,S., Cheng,D., Ching,W.K., Hancock,R.E. and Brinkman,F.S. TITLE Pseudomonas aeruginosa Genome Database and PseudoCap: facilitating community-based, continually updated, genome annotation JOURNAL Nucleic acids Res. 33 (DATABASE ISSUE), D338-D343 (2005) PUBMED 15608211 REFERENCE 8 (residues 1 to 1746) AUTHORS Wagner,V.E., Bushnell,D., Passador,L., Brooks,A.I. and Iglewski,B.H. TITLE Microarray analysis of Pseudomonas aeruginosa quorum-sensing regulons: effects of growth phase and environment JOURNAL J. Bacteriol. 185 (7), 2080-2095 (2003) PUBMED 12644477 REFERENCE 9 (residues 1 to 1746) AUTHORS Schuster,M., Lostroh,C.P., Ogi,T. and Greenberg,E.P. TITLE Identification, timing, and signal specificity of Pseudomonas aeruginosa quorum-controlled genes: a transcriptome analysis JOURNAL J. Bacteriol. 185 (7), 2066-2079 (2003) PUBMED 12644476 REFERENCE 10 (residues 1 to 1746) AUTHORS Stover,C.K., Pham,X.Q., Erwin,A.L., Mizoguchi,S.D., Warrener,P., Hickey,M.J., Brinkman,F.S., Hufnagle,W.O., Kowalik,D.J., Lagrou,M., Garber,R.L., Goltry,L., Tolentino,E., Westbrock-Wadman,S., Yuan,Y., Brody,L.L., Coulter,S.N., Folger,K.R., Kas,A., Larbig,K., Lim,R., Smith,K., Spencer,D., Wong,G.K., Wu,Z., Paulsen,I.T., Reizer,J., Saier,M.H., Hancock,R.E., Lory,S. and Olson,M.V. TITLE Complete genome sequence of Pseudomonas aeruginosa PA01, an opportunistic pathogen JOURNAL Nature 406 (6799), 959-964 (2000) PUBMED 10984043 REFERENCE 11 (residues 1 to 1746) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (06-OCT-2010) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 12 (residues 1 to 1746) AUTHORS Winsor,G.L., Hancock,R.E. and Brinkman,F.S. CONSRTM Pseudomonas aeruginosa Community Annotation Project (PseudoCap) TITLE Direct Submission JOURNAL Submitted (08-SEP-2010) Department of Molecular Biology and Biochemisry, Simon Fraser University, 8888 University Dr., Burnaby, British Columbia V5A 1S6, Canada REMARK protein update by submitter REFERENCE 13 (residues 1 to 1746) AUTHORS Winsor,G.L., Hancock,R.E. and Brinkman,F.S. CONSRTM Pseudomonas aeruginosa Community Annotation Project (PseudoCap) TITLE Direct Submission JOURNAL Submitted (02-OCT-2008) Department of Molecular Biology and Biochemisry, Simon Fraser University, 8888 University Dr., Burnaby, British Columbia V5A 1S6, Canada REMARK protein update by submitter REFERENCE 14 (residues 1 to 1746) AUTHORS Winsor,G.L., Hancock,R.E. and Brinkman,F.S. CONSRTM Pseudomonas aeruginosa Community Annotation Project (PseudoCap) TITLE Direct Submission JOURNAL Submitted (05-JUL-2006) Department of Molecular Biology and Biochemisry, Simon Fraser University, 8888 University Dr., Burnaby, British Columbia V5A 1S6, Canada REMARK Sequence update by submitter REFERENCE 15 (residues 1 to 1746) AUTHORS Ung,K.S., Hancock,R.E. and Brinkman,F.S. CONSRTM Pseudomonas aeruginosa Community Annotation Project (PseudoCap) TITLE Direct Submission JOURNAL Submitted (04-FEB-2003) Department of Molecular Biology and Biochemistry, Simon Fraser University, 8888 University Dr., Burnaby, British Columbia V5A 1S6, Canada REFERENCE 16 (residues 1 to 1746) AUTHORS Stover,C.K., Pham,X.-Q.T., Erwin,A.L., Mizoguchi,S.D., Warrener,P., Hickey,M.J., Brinkman,F.S.L., Hufnagle,W.O., Kowalik,D.J., Lagrou,M., Garber,R.L., Goltry,L., Tolentino,E., Westbrock-Wadman,S., Yuan,Y., Brody,L.L., Coulter,S.N., Folger,K.R., Kas,A., Larbig,K., Lim,R.M., Smith,K.A., Spencer,D.H., Wong,G.K.-S., Wu,Z., Paulsen,I.T., Reizer,J., Saier,M.H., Hancock,R.E.W., Lory,S. and Olson,M.V. CONSRTM Pseudomonas aeruginosa Community Annotation Project (PseudoCap) TITLE Direct Submission JOURNAL Submitted (16-MAY-2000) Department of Medicine and Genetics, University of Washington Genome Center, University Of Washington, Box 352145, Seattle, WA 98195, USA COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to AAG07115. Method: conceptual translation. FEATURES Location/Qualifiers source 1..1746 /organism="Pseudomonas aeruginosa PAO1" /strain="PAO1" /db_xref="taxon:208964" Protein 1..1746 /product="hypothetical protein" /calculated_mol_wt=197005 Region 38..485 /region_name="DUF3686" /note="ATPase involved in DNA repair; pfam12458" /db_xref="CDD:432568" Region <573..>1135 /region_name="Smc" /note="Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; COG1196" /db_xref="CDD:440809" Region 1290..1382 /region_name="P-loop containing Nucleoside Triphosphate Hydrolases" /note="Members of the P-loop NTPase domain superfamily are characterized by a conserved nucleotide phosphate-binding motif, also referred to as the Walker A motif (GxxxxGK[S/T], where x is any residue), and the Walker B motif (hhhh[D/E], where h is a...; cl38936" /db_xref="CDD:476819" Site 1296..1303 /site_type="other" /note="Walker A motif" /db_xref="CDD:99707" Site order(1297..1304,1364) /site_type="other" /note="ATP binding site [chemical binding]" /db_xref="CDD:99707" Site 1360..1365 /site_type="other" /note="Walker B motif" /db_xref="CDD:99707" CDS 1..1746 /locus_tag="PA3728" /coded_by="complement(NC_002516.2:4173886..4179126)" /note="'Product name confidence: class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences)'" /transl_table=11 /db_xref="GeneID:880349" CONTIG join(WP_003113834.1:1..1746) ORIGIN 1 msdtqaatpa qdvldkavae ggayevlhkr lleqgqrlrq taerlnasrl eefgdsqmdv 61 igrvrirten nciardivqv gdcllfgynv figlrketgv advfslyrlv egsegyeaep 121 vplgdsflaa pgfvndfnel ytyykntrll qlairdgkll asfqigerit dirvfrwsis 181 sdgsevryid nrgerdialp apfdfewqra tremvvegrf phlnildtlf vetiggdlti 241 kvenntevgl giyreevmdk tqslddaqve farlgsllll kvlpyreeqw rylvfnsltg 301 kveridaigl aciqlpedhg iifpggyylq ngeyrtfeqs megmrfkrsv rspngedvqy 361 vfyhpeqgrn vlltynlinr qlqnplfghg yarledgrmv ifaaegeept rihpmqvwqt 421 pfcteeyaar qparsgflgr ignaelvrgv sdlydlcrei etpavsiqry sllcqntqrl 481 fdvyhwlgsd qldglapllr evaataelvl deyekvesir rqsaqamida eerhkallsg 541 llpdgwdrvq qfvdglngit aqrgslltir eyryidvarl dameaellaa hervaaatat 601 flaseqalqp llerlqsldg eaqkaetvaq lgeplaalea magdldmlss lmaslridda 661 tqrtriiesi seiyarlnqa karaeqrrkg lgssetvaqf gaqfklfgqg itnalaqaqd 721 percdeqlsr llvqleeles qfgdheqflg dilakreell etfeahkqtl lderqrkaqg 781 lldaarrild slqrrtarft qaeelnaffa adplilklre laerlrelkd svkaddvear 841 lkaardqavr alrdkselfe eggdvirlgp rhrfsvntqe ldltlmprgd alylhltgtd 901 fleplqdprl delrefwqvn lesesetlyr aeylagevla aadagrdgfs lerlqallaq 961 pdelaraird faaprykegy ekgihdhdaa ailvrllplr esagllryap sarafaslfw 1021 srrreereva gwperarssr siqqmfgrdd gllalrgeva aamrallaeq pialdpqhid 1081 eaaeylvwel saerpeftfs kyarqlqegl klrlqgarlw ddyrqtlerl gerpaaqwel 1141 agnwlrglcg daefqplaay ldeavalsll deemprrite vdlrfqvdgl mgehprifer 1201 glalavddff grlrrhrqqf lpglrryqal rqeivehere alrlaefkpr plssfvrnkl 1261 indvylgvig dnlakqmgtv genkrtdlmg llmlisppgy gkttlmeyva hrlglifmki 1321 ngpalghevr sldpgqapda tsrqelekln lalemgnnvm lyvddiqhth peflqkfisl 1381 cdgtrrvegv wkgrtktydm rgrkfcvvma gnpytesgev fripdmlanr adiynlgdtl 1441 sgmqeafsls yienaltsnp vlaplatrdm advyrfvaka egkpfssnel ahgysgaein 1501 eisstlqrlm qvrdvvlkvn qqyiasaaqa dqyrseppfk lqgsyrnmnk maekisavmn 1561 daellqliad hyqgesqllt tgaeenllkl aelrgnqspe qaerwaqikr dflrnksmgg 1621 sdadvggrlv aqlndlvesv rglarepqpv qpapwdella glrqlgqgap alnvevtapa 1681 qpgvqqvles laaclqdsfl plikvmdrki dvdlrthnri neissrldel grllggeqrp 1741 lendqp