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LOCUS NP_252177 1099 aa linear CON 24-JAN-2019 ACCESSION NP_252177 VERSION NP_252177.1 DBLINK BioProject: PRJNA57945 Assembly: GCF_000006765.1 DBSOURCE REFSEQ: accession NC_002516.2 KEYWORDS RefSeq. SOURCE Pseudomonas aeruginosa PAO1 ORGANISM Pseudomonas aeruginosa PAO1 Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas. REFERENCE 1 (residues 1 to 1099) AUTHORS Winsor,G.L., Van Rossum,T., Lo,R., Khaira,B., Whiteside,M.D., Hancock,R.E. and Brinkman,F.S. TITLE Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes JOURNAL Nucleic acids Res. 37 (DATABASE ISSUE), D483-D488 (2009) PUBMED 18978025 REFERENCE 2 (residues 1 to 1099) AUTHORS Cirz,R.T., O'Neill,B.M., Hammond,J.A., Head,S.R. and Romesberg,F.E. TITLE Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin JOURNAL J. Bacteriol. 188 (20), 7101-7110 (2006) PUBMED 17015649 REFERENCE 3 (residues 1 to 1099) AUTHORS Palmer,K.L., Mashburn,L.M., Singh,P.K. and Whiteley,M. TITLE Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology JOURNAL J. Bacteriol. 187 (15), 5267-5277 (2005) PUBMED 16030221 REFERENCE 4 (residues 1 to 1099) AUTHORS Salunkhe,P., Smart,C.H., Morgan,J.A., Panagea,S., Walshaw,M.J., Hart,C.A., Geffers,R., Tummler,B. and Winstanley,C. TITLE A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance JOURNAL J. Bacteriol. 187 (14), 4908-4920 (2005) PUBMED 15995206 REFERENCE 5 (residues 1 to 1099) AUTHORS Filiatrault,M.J., Wagner,V.E., Bushnell,D., Haidaris,C.G., Iglewski,B.H. and Passador,L. TITLE Effect of anaerobiosis and nitrate on gene expression in Pseudomonas aeruginosa JOURNAL Infect. Immun. 73 (6), 3764-3772 (2005) PUBMED 15908409 REFERENCE 6 (residues 1 to 1099) AUTHORS Rasmussen,T.B., Bjarnsholt,T., Skindersoe,M.E., Hentzer,M., Kristoffersen,P., Kote,M., Nielsen,J., Eberl,L. and Givskov,M. TITLE Screening for quorum-sensing inhibitors (QSI) by use of a novel genetic system, the QSI selector JOURNAL J. Bacteriol. 187 (5), 1799-1814 (2005) PUBMED 15716452 REFERENCE 7 (residues 1 to 1099) AUTHORS Winsor,G.L., Lo,R., Sui,S.J., Ung,K.S., Huang,S., Cheng,D., Ching,W.K., Hancock,R.E. and Brinkman,F.S. TITLE Pseudomonas aeruginosa Genome Database and PseudoCap: facilitating community-based, continually updated, genome annotation JOURNAL Nucleic acids Res. 33 (DATABASE ISSUE), D338-D343 (2005) PUBMED 15608211 REFERENCE 8 (residues 1 to 1099) AUTHORS Wagner,V.E., Bushnell,D., Passador,L., Brooks,A.I. and Iglewski,B.H. TITLE Microarray analysis of Pseudomonas aeruginosa quorum-sensing regulons: effects of growth phase and environment JOURNAL J. Bacteriol. 185 (7), 2080-2095 (2003) PUBMED 12644477 REFERENCE 9 (residues 1 to 1099) AUTHORS Schuster,M., Lostroh,C.P., Ogi,T. and Greenberg,E.P. TITLE Identification, timing, and signal specificity of Pseudomonas aeruginosa quorum-controlled genes: a transcriptome analysis JOURNAL J. Bacteriol. 185 (7), 2066-2079 (2003) PUBMED 12644476 REFERENCE 10 (residues 1 to 1099) AUTHORS Stover,C.K., Pham,X.Q., Erwin,A.L., Mizoguchi,S.D., Warrener,P., Hickey,M.J., Brinkman,F.S., Hufnagle,W.O., Kowalik,D.J., Lagrou,M., Garber,R.L., Goltry,L., Tolentino,E., Westbrock-Wadman,S., Yuan,Y., Brody,L.L., Coulter,S.N., Folger,K.R., Kas,A., Larbig,K., Lim,R., Smith,K., Spencer,D., Wong,G.K., Wu,Z., Paulsen,I.T., Reizer,J., Saier,M.H., Hancock,R.E., Lory,S. and Olson,M.V. TITLE Complete genome sequence of Pseudomonas aeruginosa PA01, an opportunistic pathogen JOURNAL Nature 406 (6799), 959-964 (2000) PUBMED 10984043 REFERENCE 11 (residues 1 to 1099) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (06-OCT-2010) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 12 (residues 1 to 1099) AUTHORS Winsor,G.L., Hancock,R.E. and Brinkman,F.S. CONSRTM Pseudomonas aeruginosa Community Annotation Project (PseudoCap) TITLE Direct Submission JOURNAL Submitted (08-SEP-2010) Department of Molecular Biology and Biochemisry, Simon Fraser University, 8888 University Dr., Burnaby, British Columbia V5A 1S6, Canada REMARK protein update by submitter REFERENCE 13 (residues 1 to 1099) AUTHORS Winsor,G.L., Hancock,R.E. and Brinkman,F.S. CONSRTM Pseudomonas aeruginosa Community Annotation Project (PseudoCap) TITLE Direct Submission JOURNAL Submitted (02-OCT-2008) Department of Molecular Biology and Biochemisry, Simon Fraser University, 8888 University Dr., Burnaby, British Columbia V5A 1S6, Canada REMARK protein update by submitter REFERENCE 14 (residues 1 to 1099) AUTHORS Winsor,G.L., Hancock,R.E. and Brinkman,F.S. CONSRTM Pseudomonas aeruginosa Community Annotation Project (PseudoCap) TITLE Direct Submission JOURNAL Submitted (05-JUL-2006) Department of Molecular Biology and Biochemisry, Simon Fraser University, 8888 University Dr., Burnaby, British Columbia V5A 1S6, Canada REMARK Sequence update by submitter REFERENCE 15 (residues 1 to 1099) AUTHORS Ung,K.S., Hancock,R.E. and Brinkman,F.S. CONSRTM Pseudomonas aeruginosa Community Annotation Project (PseudoCap) TITLE Direct Submission JOURNAL Submitted (04-FEB-2003) Department of Molecular Biology and Biochemistry, Simon Fraser University, 8888 University Dr., Burnaby, British Columbia V5A 1S6, Canada REFERENCE 16 (residues 1 to 1099) AUTHORS Stover,C.K., Pham,X.-Q.T., Erwin,A.L., Mizoguchi,S.D., Warrener,P., Hickey,M.J., Brinkman,F.S.L., Hufnagle,W.O., Kowalik,D.J., Lagrou,M., Garber,R.L., Goltry,L., Tolentino,E., Westbrock-Wadman,S., Yuan,Y., Brody,L.L., Coulter,S.N., Folger,K.R., Kas,A., Larbig,K., Lim,R.M., Smith,K.A., Spencer,D.H., Wong,G.K.-S., Wu,Z., Paulsen,I.T., Reizer,J., Saier,M.H., Hancock,R.E.W., Lory,S. and Olson,M.V. CONSRTM Pseudomonas aeruginosa Community Annotation Project (PseudoCap) TITLE Direct Submission JOURNAL Submitted (16-MAY-2000) Department of Medicine and Genetics, University of Washington Genome Center, University Of Washington, Box 352145, Seattle, WA 98195, USA COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to AAG06875. Method: conceptual translation. FEATURES Location/Qualifiers source 1..1099 /organism="Pseudomonas aeruginosa PAO1" /strain="PAO1" /db_xref="taxon:208964" Protein 1..1099 /product="phospholipase D" /calculated_mol_wt=122211 Region 51..200 /region_name="PLDc_vPLD1_2_like_1" /note="Catalytic domain, repeat 1, of vertebrate phospholipases, PLD1 and PLD2, and similar proteins; cd09104" /db_xref="CDD:197203" Site order(167,169,182,184,195) /site_type="active" /note="putative active site [active]" /db_xref="CDD:197203" Site 167 /site_type="active" /note="catalytic site [active]" /db_xref="CDD:197203" Region <461..1003 /region_name="PLN02866" /note="phospholipase D" /db_xref="CDD:215467" Region 600..894 /region_name="PLDc_vPLD1_2_yPLD_like_2" /note="Catalytic domain, repeat 2, of vertebrate phospholipases, PLD1 and PLD2, yeast PLDs, and similar proteins; cd09141" /db_xref="CDD:197239" Site order(855,857,870,872,885) /site_type="active" /note="putative active site [active]" /db_xref="CDD:197239" Site 855 /site_type="active" /note="catalytic site [active]" /db_xref="CDD:197239" CDS 1..1099 /gene="pldA" /locus_tag="PA3487" /coded_by="NC_002516.2:3902663..3905962" /note="Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)" /transl_table=11 /db_xref="GeneID:880040" CONTIG join(WP_003112916.1:1..1099) ORIGIN 1 mlqkkpyngl hekelnqinq qdgspcvais apgcfikgsn lfsekragnr vrffttgrdy 61 fsdlasalds asssifitgw qvnydvlldg rrslwqclrq alerspalkv yvmpwlspsg 121 slgtydfetm lavfqlnagl eggarafctp aiqqsdmqgl gvafshhqks vvidnrigyv 181 ggidlaygrr ddndfsldas grrgndaynp glphlgwmae dehvssmglm matlfdlsrp 241 lasltlhapt lrlspfphia asdepllsip lapsraraln gaaylsdlfr spmlpslqwl 301 graynsskeg ldegferlda lrrqmvassi raianliadn ldalpiepel errlrawlee 361 lrtaalnlpe alriksllli nqwmsetelg qvltlisgkg fedipqnlsg kagelagslf 421 wtlhrlmqar agghqqpyry ldeapqplas pdnarlaadq prmpwqdvhc riegpsvydl 481 arnfidrwng qqaylaktpa lqdtalvrsa leavmkwlns laaaagleny ldekrnlrle 541 ldpptpcwin apeqlpqepe vrrggmtvqv lrsaaarmle qeqagrlgag vnlplqvgvs 601 tegvqsnckd amllaisgaq qfiyienqff qsefgkegev fkdlplsgpm aslrdvgslr 661 rdfvvrirle ealeqrdlwl ldwaevekia qepgtearqf lksmlamwgv naqgwlthkl 721 geaqhgllne igealarrie raiqrehpfh vylvlpvhpe galnvpnimh qvhltqqslv 781 fgeqslvkri qrqmalkale gksdpaqare iierkdargr pvyeqqdwsr yltllnlrtw 841 avlggrvvte qiyvhsklli addrvailgs anindrslqg erdselavmv rdsepltvrl 901 dgkndaivgk aihqlrvnlw kkhfglsqgp ggfvkpasel saylsipaaq eaweaiqtla 961 kentrayert fnfipqnisq tqlqltpepp kgfedgfpas iwptwayrkp gelraggqlm 1021 epmpyqeifw rssnltsvkt fpppngvsgf italptswtr gerndsglnl silahqdsrs 1081 lptqvamngd ssaqgkhrt