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cytochrome o ubiquinol oxidase subunit I [Pseudomonas aeruginosa


LOCUS       NP_250009                658 aa            linear   CON 24-JAN-2019
            PAO1].
ACCESSION   NP_250009
VERSION     NP_250009.1
DBLINK      BioProject: PRJNA57945
            Assembly: GCF_000006765.1
DBSOURCE    REFSEQ: accession NC_002516.2
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa PAO1
  ORGANISM  Pseudomonas aeruginosa PAO1
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (residues 1 to 658)
  AUTHORS   Winsor,G.L., Van Rossum,T., Lo,R., Khaira,B., Whiteside,M.D.,
            Hancock,R.E. and Brinkman,F.S.
  TITLE     Pseudomonas Genome Database: facilitating user-friendly,
            comprehensive comparisons of microbial genomes
  JOURNAL   Nucleic acids Res. 37 (DATABASE ISSUE), D483-D488 (2009)
   PUBMED   18978025
REFERENCE   2  (residues 1 to 658)
  AUTHORS   Cirz,R.T., O'Neill,B.M., Hammond,J.A., Head,S.R. and Romesberg,F.E.
  TITLE     Defining the Pseudomonas aeruginosa SOS response and its role in
            the global response to the antibiotic ciprofloxacin
  JOURNAL   J. Bacteriol. 188 (20), 7101-7110 (2006)
   PUBMED   17015649
REFERENCE   3  (residues 1 to 658)
  AUTHORS   Palmer,K.L., Mashburn,L.M., Singh,P.K. and Whiteley,M.
  TITLE     Cystic fibrosis sputum supports growth and cues key aspects of
            Pseudomonas aeruginosa physiology
  JOURNAL   J. Bacteriol. 187 (15), 5267-5277 (2005)
   PUBMED   16030221
REFERENCE   4  (residues 1 to 658)
  AUTHORS   Salunkhe,P., Smart,C.H., Morgan,J.A., Panagea,S., Walshaw,M.J.,
            Hart,C.A., Geffers,R., Tummler,B. and Winstanley,C.
  TITLE     A cystic fibrosis epidemic strain of Pseudomonas aeruginosa
            displays enhanced virulence and antimicrobial resistance
  JOURNAL   J. Bacteriol. 187 (14), 4908-4920 (2005)
   PUBMED   15995206
REFERENCE   5  (residues 1 to 658)
  AUTHORS   Filiatrault,M.J., Wagner,V.E., Bushnell,D., Haidaris,C.G.,
            Iglewski,B.H. and Passador,L.
  TITLE     Effect of anaerobiosis and nitrate on gene expression in
            Pseudomonas aeruginosa
  JOURNAL   Infect. Immun. 73 (6), 3764-3772 (2005)
   PUBMED   15908409
REFERENCE   6  (residues 1 to 658)
  AUTHORS   Rasmussen,T.B., Bjarnsholt,T., Skindersoe,M.E., Hentzer,M.,
            Kristoffersen,P., Kote,M., Nielsen,J., Eberl,L. and Givskov,M.
  TITLE     Screening for quorum-sensing inhibitors (QSI) by use of a novel
            genetic system, the QSI selector
  JOURNAL   J. Bacteriol. 187 (5), 1799-1814 (2005)
   PUBMED   15716452
REFERENCE   7  (residues 1 to 658)
  AUTHORS   Winsor,G.L., Lo,R., Sui,S.J., Ung,K.S., Huang,S., Cheng,D.,
            Ching,W.K., Hancock,R.E. and Brinkman,F.S.
  TITLE     Pseudomonas aeruginosa Genome Database and PseudoCap: facilitating
            community-based, continually updated, genome annotation
  JOURNAL   Nucleic acids Res. 33 (DATABASE ISSUE), D338-D343 (2005)
   PUBMED   15608211
REFERENCE   8  (residues 1 to 658)
  AUTHORS   Wagner,V.E., Bushnell,D., Passador,L., Brooks,A.I. and
            Iglewski,B.H.
  TITLE     Microarray analysis of Pseudomonas aeruginosa quorum-sensing
            regulons: effects of growth phase and environment
  JOURNAL   J. Bacteriol. 185 (7), 2080-2095 (2003)
   PUBMED   12644477
REFERENCE   9  (residues 1 to 658)
  AUTHORS   Schuster,M., Lostroh,C.P., Ogi,T. and Greenberg,E.P.
  TITLE     Identification, timing, and signal specificity of Pseudomonas
            aeruginosa quorum-controlled genes: a transcriptome analysis
  JOURNAL   J. Bacteriol. 185 (7), 2066-2079 (2003)
   PUBMED   12644476
REFERENCE   10 (residues 1 to 658)
  AUTHORS   Stover,C.K., Pham,X.Q., Erwin,A.L., Mizoguchi,S.D., Warrener,P.,
            Hickey,M.J., Brinkman,F.S., Hufnagle,W.O., Kowalik,D.J., Lagrou,M.,
            Garber,R.L., Goltry,L., Tolentino,E., Westbrock-Wadman,S., Yuan,Y.,
            Brody,L.L., Coulter,S.N., Folger,K.R., Kas,A., Larbig,K., Lim,R.,
            Smith,K., Spencer,D., Wong,G.K., Wu,Z., Paulsen,I.T., Reizer,J.,
            Saier,M.H., Hancock,R.E., Lory,S. and Olson,M.V.
  TITLE     Complete genome sequence of Pseudomonas aeruginosa PA01, an
            opportunistic pathogen
  JOURNAL   Nature 406 (6799), 959-964 (2000)
   PUBMED   10984043
REFERENCE   11 (residues 1 to 658)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-OCT-2010) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   12 (residues 1 to 658)
  AUTHORS   Winsor,G.L., Hancock,R.E. and Brinkman,F.S.
  CONSRTM   Pseudomonas aeruginosa Community Annotation Project (PseudoCap)
  TITLE     Direct Submission
  JOURNAL   Submitted (08-SEP-2010) Department of Molecular Biology and
            Biochemisry, Simon Fraser University, 8888 University Dr., Burnaby,
            British Columbia V5A 1S6, Canada
  REMARK    protein update by submitter
REFERENCE   13 (residues 1 to 658)
  AUTHORS   Winsor,G.L., Hancock,R.E. and Brinkman,F.S.
  CONSRTM   Pseudomonas aeruginosa Community Annotation Project (PseudoCap)
  TITLE     Direct Submission
  JOURNAL   Submitted (02-OCT-2008) Department of Molecular Biology and
            Biochemisry, Simon Fraser University, 8888 University Dr., Burnaby,
            British Columbia V5A 1S6, Canada
  REMARK    protein update by submitter
REFERENCE   14 (residues 1 to 658)
  AUTHORS   Winsor,G.L., Hancock,R.E. and Brinkman,F.S.
  CONSRTM   Pseudomonas aeruginosa Community Annotation Project (PseudoCap)
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUL-2006) Department of Molecular Biology and
            Biochemisry, Simon Fraser University, 8888 University Dr., Burnaby,
            British Columbia V5A 1S6, Canada
  REMARK    Sequence update by submitter
REFERENCE   15 (residues 1 to 658)
  AUTHORS   Ung,K.S., Hancock,R.E. and Brinkman,F.S.
  CONSRTM   Pseudomonas aeruginosa Community Annotation Project (PseudoCap)
  TITLE     Direct Submission
  JOURNAL   Submitted (04-FEB-2003) Department of Molecular Biology and
            Biochemistry, Simon Fraser University, 8888 University Dr.,
            Burnaby, British Columbia V5A 1S6, Canada
REFERENCE   16 (residues 1 to 658)
  AUTHORS   Stover,C.K., Pham,X.-Q.T., Erwin,A.L., Mizoguchi,S.D., Warrener,P.,
            Hickey,M.J., Brinkman,F.S.L., Hufnagle,W.O., Kowalik,D.J.,
            Lagrou,M., Garber,R.L., Goltry,L., Tolentino,E.,
            Westbrock-Wadman,S., Yuan,Y., Brody,L.L., Coulter,S.N.,
            Folger,K.R., Kas,A., Larbig,K., Lim,R.M., Smith,K.A., Spencer,D.H.,
            Wong,G.K.-S., Wu,Z., Paulsen,I.T., Reizer,J., Saier,M.H.,
            Hancock,R.E.W., Lory,S. and Olson,M.V.
  CONSRTM   Pseudomonas aeruginosa Community Annotation Project (PseudoCap)
  TITLE     Direct Submission
  JOURNAL   Submitted (16-MAY-2000) Department of Medicine and Genetics,
            University of Washington Genome Center, University Of Washington,
            Box 352145, Seattle, WA 98195, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AAG04707.
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..658
                     /organism="Pseudomonas aeruginosa PAO1"
                     /strain="PAO1"
                     /db_xref="taxon:208964"
     Protein         1..658
                     /product="cytochrome o ubiquinol oxidase subunit I"
                     /calculated_mol_wt=73804
     Region          2..647
                     /region_name="CyoB"
                     /note="cytochrome o ubiquinol oxidase, subunit I;
                     TIGR02843"
                     /db_xref="CDD:131890"
     Site            order(61,125,135,142,145,200..201,207,211)
                     /site_type="active"
                     /note="D-pathway [active]"
                     /db_xref="CDD:238832"
     Site            order(71,75,78..79,98,101..103)
                     /site_type="other"
                     /note="Putative ubiquinol binding site [chemical binding]"
                     /db_xref="CDD:238832"
     Site            order(106,421,425,467,505)
                     /site_type="other"
                     /note="Low-spin heme (heme b) binding site [chemical
                     binding]"
                     /db_xref="CDD:238832"
     Site            order(271,276..277,407,411..412,481)
                     /site_type="other"
                     /note="Putative water exit pathway"
                     /db_xref="CDD:238832"
     Site            order(284,333..334,419)
                     /site_type="other"
                     /note="Binuclear center (heme o3/CuB) [ion binding]"
                     /db_xref="CDD:238832"
     Site            order(284,288,299,333..334,359,362)
                     /site_type="active"
                     /note="K-pathway [active]"
                     /db_xref="CDD:238832"
     Site            order(334,411..412,481..482)
                     /site_type="other"
                     /note="Putative proton exit pathway"
                     /db_xref="CDD:238832"
     CDS             1..658
                     /gene="cyoB"
                     /locus_tag="PA1318"
                     /coded_by="NC_002516.2:1429082..1431058"
                     /note="Product name confidence: class 2 (High similarity
                     to functionally studied protein)"
                     /transl_table=11
                     /db_xref="GeneID:881481"
CONTIG      join(WP_003112371.1:1..658)
ORIGIN      
        1 mfgkltlsav pyhepivmvt lavvallglg vvgaityyrk wtylwtewlt svdhkkigvm
       61 yivvalvmlv rgfadaimmr gqlalaegan hgylppehyd qiftahgvim iifmampfmt
      121 glmnlavplq igardvafpf lnslsfwllv vsamlvnvsl glgefartgw vaypplsela
      181 yspgvgvdyy iwalqisgmg tlltginflv tvfkmrtpgm klmqmpiftw tctfaniliv
      241 asfpiltaal gllsldryld mhfftnelgg nammyinlfw awghpevyil ilpafgifse
      301 vtatfagkrm fgyksmvwas aaitflgftv wlhhfftmgs ggdvngffgv atmlisiptg
      361 vklfnwlfti ykgrlrfstp ilwtlgfmvt ftiggmtgvl laipgadfll hnslfliahf
      421 hntiiggavf gylagfafwf pkafgftlde kwgkrsfwcw lvgfymafmp lyilgfmgmt
      481 rrlnhydnpl wkpylvvaff gavlifcgia cqliqlfvsv rnrkqladvn gdpwegrtle
      541 watsspppfy nfaelpkvqd vdafhdmkka gtayrklpay qpihmpknta agfsiavfaf
      601 vfgfaaiwhi wwlmavgfvg migsfivrsy nqdvdyyvqp eeiekiesar fqqlakqv