2-hydroxyacid dehydrogenase [Klebsiella pneumoniae subsp.

LOCUS       YP_005229374             323 aa            linear   CON 02-JUN-2020
            pneumoniae HS11286].
ACCESSION   YP_005229374
VERSION     YP_005229374.1
DBLINK      BioProject: PRJNA84387
            Assembly: GCF_000240185.1
DBSOURCE    REFSEQ: accession NC_016845.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae subsp. pneumoniae HS11286
  ORGANISM  Klebsiella pneumoniae subsp. pneumoniae HS11286
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 323)
  AUTHORS   Liu,P., Li,P., Jiang,X., Bi,D., Xie,Y., Tai,C., Deng,Z.,
            Rajakumar,K. and Ou,H.Y.
  TITLE     Complete genome sequence of Klebsiella pneumoniae subsp. pneumoniae
            HS11286, a multidrug-resistant strain isolated from human sputum
  JOURNAL   J. Bacteriol. 194 (7), 1841-1842 (2012)
   PUBMED   22408243
REFERENCE   2  (residues 1 to 323)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-FEB-2012) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 323)
  AUTHORS   Ou,H.-Y., Jiang,X., Liu,P. and Li,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-DEC-2011) State Key Laboratory of Microbial
            Metabolism, Shanghai Jiaotong University, 1954 Huashan Road,
            Shanghai 200030, China
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence is identical to AEW63772.
            RefSeq Category: Reference Genome
                        CLI: Clinical Isolate
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Klebsiella pneumoniae subsp. pneumoniae
                     HS11286"
                     /strain="HS11286"
                     /sub_species="pneumoniae"
                     /db_xref="taxon:1125630"
     Protein         1..323
                     /product="2-hydroxyacid dehydrogenase"
                     /calculated_mol_wt=35283
     Region          1..322
                     /region_name="PRK15409"
                     /note="glyoxylate/hydroxypyruvate reductase GhrB"
                     /db_xref="CDD:185307"
     Site            order(9..10,12,52,53,73,101..102,105..106,108..109,112,
                     116,118,126,128,130,133..139,140..144,162..163,167..168,
                     266..267,275,281..287,289..292,294)
                     /site_type="other"
                     /note="dimerization interface [polypeptide binding]"
                     /db_xref="CDD:240626"
     Site            order(74..76,99,237,285,288)
                     /site_type="other"
                     /note="ligand binding site [chemical binding]"
                     /db_xref="CDD:240626"
     Site            order(75..76,103,152..156,175..177,180,207..209,213..214,
                     235..237,261..262,285,287..288)
                     /site_type="other"
                     /note="NADP binding site [chemical binding]"
                     /db_xref="CDD:240626"
     CDS             1..323
                     /locus_tag="KPHS_50740"
                     /coded_by="NC_016845.1:5093357..5094328"
                     /transl_table=11
                     /db_xref="GeneID:11850145"
CONTIG      join(WP_002921928.1:1..323)
ORIGIN      
        1 mkpsvilykt lpddllqhle ehfsvtqvkn lrpetvsqha eafaqaegll gssekvdaal
       61 lekmpklrat stvsvgydnf dvealnarrv llmhtptvlt etvadtvmal vlstarrvve
      121 vaervkagew tksigpdwfg tdvhhktlgi vgmgrigmal aqrahfgfgm pilynarrqh
      181 pqaeerfnar ycdldtllqe adfvclilpl seethhlfgq aqfakmkssa ifinagrgpv
      241 vdeqaliaal qngeihaagl dvfeheplak dspllslpnv valphigsat hetrynmaac
      301 avdnlidaln gnvekncvnp qvk