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2,4-dienoyl-CoA reductase [Klebsiella pneumoniae subsp. pneumoniae


LOCUS       YP_005228943             673 aa            linear   CON 02-JUN-2020
            HS11286].
ACCESSION   YP_005228943
VERSION     YP_005228943.1
DBLINK      BioProject: PRJNA84387
            Assembly: GCF_000240185.1
DBSOURCE    REFSEQ: accession NC_016845.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae subsp. pneumoniae HS11286
  ORGANISM  Klebsiella pneumoniae subsp. pneumoniae HS11286
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 673)
  AUTHORS   Liu,P., Li,P., Jiang,X., Bi,D., Xie,Y., Tai,C., Deng,Z.,
            Rajakumar,K. and Ou,H.Y.
  TITLE     Complete genome sequence of Klebsiella pneumoniae subsp. pneumoniae
            HS11286, a multidrug-resistant strain isolated from human sputum
  JOURNAL   J. Bacteriol. 194 (7), 1841-1842 (2012)
   PUBMED   22408243
REFERENCE   2  (residues 1 to 673)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-FEB-2012) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 673)
  AUTHORS   Ou,H.-Y., Jiang,X., Liu,P. and Li,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-DEC-2011) State Key Laboratory of Microbial
            Metabolism, Shanghai Jiaotong University, 1954 Huashan Road,
            Shanghai 200030, China
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence is identical to AEW63341.
            RefSeq Category: Reference Genome
                        CLI: Clinical Isolate
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..673
                     /organism="Klebsiella pneumoniae subsp. pneumoniae
                     HS11286"
                     /strain="HS11286"
                     /sub_species="pneumoniae"
                     /db_xref="taxon:1125630"
     Protein         1..673
                     /product="2,4-dienoyl-CoA reductase"
                     /calculated_mol_wt=72090
     Region          7..359
                     /region_name="DCR_FMN"
                     /note="2,4-dienoyl-CoA reductase (DCR) FMN-binding domain.
                     DCR in E. coli is an iron-sulfur flavoenzyme which
                     contains FMN, FAD, and a 4Fe-4S cluster. It is also a
                     monomer, unlike that of its eukaryotic counterparts which
                     form homotetramers and lack the...; cd02930"
                     /db_xref="CDD:239240"
     Site            order(26,28,60,102,166,168,177,216,254,257,312..313,336,
                     339,343,355)
                     /site_type="active"
                     /db_xref="CDD:239240"
     Site            order(26,28,60,102,216,312..313)
                     /site_type="other"
                     /note="FMN binding site [chemical binding]"
                     /db_xref="CDD:239240"
     Site            order(166,168,177,254,257)
                     /site_type="other"
                     /note="2,4-decadienoyl-CoA binding site"
                     /db_xref="CDD:239240"
     Site            168
                     /site_type="active"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:239240"
     Site            order(336,339,343,355)
                     /site_type="other"
                     /note="4Fe-4S cluster binding site [ion binding]"
                     /db_xref="CDD:239240"
     Region          <376..>513
                     /region_name="GltD"
                     /note="NADPH-dependent glutamate synthase beta chain or
                     related oxidoreductase [Amino acid transport and
                     metabolism, General function prediction only]; COG0493"
                     /db_xref="CDD:440259"
     Region          401..>653
                     /region_name="FadH2"
                     /note="NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur
                     reductase, or a related oxidoreductase [Lipid transport
                     and metabolism]; COG0446"
                     /db_xref="CDD:440215"
     CDS             1..673
                     /locus_tag="KPHS_46430"
                     /coded_by="NC_016845.1:4667987..4670008"
                     /transl_table=11
                     /db_xref="GeneID:11849698"
CONTIG      join(WP_004181395.1:1..673)
ORIGIN      
        1 msrypslfap lelgfttlkn rvlmgsmhtg leelpdgaqr laafyaerar hgvalivtgg
       61 iapapsgvtm aggavlndas hlahhrhitd avhqeggkia lqilhtgrys yqpalvapsa
      121 lqapinrftp helshdeilt liddfahcaq lareagydgv evmgsegyli neflaartnq
      181 rddqwggdya rrmrfavevv kavrqraghd fiiiyrlsml dlvndgstla evtelakaie
      241 aagatiintg igwheaript iatpvprgaf swvtrklkga vsiplittnr indpqvaedi
      301 largdadmvs marpfladae fiskaqddra dqintcigcn qacldrifvg kvtsclvnpr
      361 achetlmpvl panapkrlav vgagpaglaf avnaaarghh vtlfdalpei ggqfniakqi
      421 pgkeefhetl ryyrtmldlh gvdlrlntrv ttddllafde tilatgiapr lpaidgidhp
      481 kvlsyldvlr dkapvgakva iigcggigfd tamflsqsga atsqdigefc rewgidtslq
      541 tagglsaegp qlsksprqiv mlqrkaskpg eglgkttgwi hratllargv kmipavsyek
      601 iddeglhvti ggerqllavd qvvicagqep rreladplra agktvhligg cdvaaeldar
      661 raiaqgtkla lai