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cystathionine-beta-synthase [Klebsiella pneumoniae subsp.


LOCUS       YP_005228836             458 aa            linear   CON 02-JUN-2020
            pneumoniae HS11286].
ACCESSION   YP_005228836
VERSION     YP_005228836.1
DBLINK      BioProject: PRJNA84387
            Assembly: GCF_000240185.1
DBSOURCE    REFSEQ: accession NC_016845.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae subsp. pneumoniae HS11286
  ORGANISM  Klebsiella pneumoniae subsp. pneumoniae HS11286
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 458)
  AUTHORS   Liu,P., Li,P., Jiang,X., Bi,D., Xie,Y., Tai,C., Deng,Z.,
            Rajakumar,K. and Ou,H.Y.
  TITLE     Complete genome sequence of Klebsiella pneumoniae subsp. pneumoniae
            HS11286, a multidrug-resistant strain isolated from human sputum
  JOURNAL   J. Bacteriol. 194 (7), 1841-1842 (2012)
   PUBMED   22408243
REFERENCE   2  (residues 1 to 458)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-FEB-2012) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 458)
  AUTHORS   Ou,H.-Y., Jiang,X., Liu,P. and Li,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-DEC-2011) State Key Laboratory of Microbial
            Metabolism, Shanghai Jiaotong University, 1954 Huashan Road,
            Shanghai 200030, China
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence is identical to AEW63234.
            RefSeq Category: Reference Genome
                        CLI: Clinical Isolate
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Klebsiella pneumoniae subsp. pneumoniae
                     HS11286"
                     /strain="HS11286"
                     /sub_species="pneumoniae"
                     /db_xref="taxon:1125630"
     Protein         1..458
                     /product="cystathionine-beta-synthase"
                     /calculated_mol_wt=49981
     Region          3..311
                     /region_name="CysK"
                     /note="Cysteine synthase [Amino acid transport and
                     metabolism]; COG0031"
                     /db_xref="CDD:439802"
     Region          334..451
                     /region_name="CBS_pair_CBS"
                     /note="Two tandem repeats of the cystathionine
                     beta-synthase (CBS pair) domains associated with the
                     pyridoxal-phosphate (PALP) dependent enzyme domain;
                     cd04608"
                     /db_xref="CDD:341382"
     Site            order(342,344,346,368..370,430,442,444,446..447,450)
                     /site_type="other"
                     /note="ligand binding site II [chemical binding]"
                     /db_xref="CDD:341382"
     Region          342..405
                     /region_name="CBS repeat"
                     /note="CBS repeat [structural motif]"
                     /db_xref="CDD:341382"
     Site            order(368,380,384..385,388,410,430..432,446)
                     /site_type="other"
                     /note="putative ligand binding site I [chemical binding]"
                     /db_xref="CDD:341382"
     Region          410..450
                     /region_name="CBS repeat"
                     /note="CBS repeat [structural motif]"
                     /db_xref="CDD:341382"
     CDS             1..458
                     /locus_tag="KPHS_45360"
                     /coded_by="NC_016845.1:4562338..4563714"
                     /transl_table=11
                     /db_xref="GeneID:11849589"
CONTIG      join(WP_004217775.1:1..458)
ORIGIN      
        1 mvmslfhsvs dlightpllq lhkldtgpcs lflklenqnp ggsikdrval smineaerqg
       61 klapggtiie atagntglgl aliaaqknyr lilvvpdkms rekifhlral gatvlltrsd
      121 vnkghpayyq dyarrladet pgafyidqfn ndanplahat stapelyqql egdidaivvg
      181 vgsggtlggl qawfaehspk tefiladpag siladqvdtg rygetgswlv egigedfipp
      241 larlegvhta yrvsdreafh tarqllqveg vlagsstgtl lsaalrycra qsrpkrvvtf
      301 acdsgnkyls kmfnddwmrq qgliarpeqg dlsdfialrh degatvtaap ddtlaavftr
      361 mrlydisqlp vledgrvvgi vdewdlirhv qgdrqrfslp vseamsrhve tldkrapese
      421 lqaildrglv aviadntrfl glvtrsdvlt awrnrvaq