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alanine racemase [Klebsiella pneumoniae subsp. pneumoniae HS11286].


LOCUS       YP_005227619             356 aa            linear   CON 02-JUN-2020
ACCESSION   YP_005227619
VERSION     YP_005227619.1
DBLINK      BioProject: PRJNA84387
            Assembly: GCF_000240185.1
DBSOURCE    REFSEQ: accession NC_016845.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae subsp. pneumoniae HS11286
  ORGANISM  Klebsiella pneumoniae subsp. pneumoniae HS11286
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 356)
  AUTHORS   Liu,P., Li,P., Jiang,X., Bi,D., Xie,Y., Tai,C., Deng,Z.,
            Rajakumar,K. and Ou,H.Y.
  TITLE     Complete genome sequence of Klebsiella pneumoniae subsp. pneumoniae
            HS11286, a multidrug-resistant strain isolated from human sputum
  JOURNAL   J. Bacteriol. 194 (7), 1841-1842 (2012)
   PUBMED   22408243
REFERENCE   2  (residues 1 to 356)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-FEB-2012) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 356)
  AUTHORS   Ou,H.-Y., Jiang,X., Liu,P. and Li,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-DEC-2011) State Key Laboratory of Microbial
            Metabolism, Shanghai Jiaotong University, 1954 Huashan Road,
            Shanghai 200030, China
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence is identical to AEW62017.
            RefSeq Category: Reference Genome
                        CLI: Clinical Isolate
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..356
                     /organism="Klebsiella pneumoniae subsp. pneumoniae
                     HS11286"
                     /strain="HS11286"
                     /sub_species="pneumoniae"
                     /db_xref="taxon:1125630"
     Protein         1..356
                     /product="alanine racemase"
                     /calculated_mol_wt=38601
     Region          2..356
                     /region_name="dadX"
                     /note="catabolic alanine racemase; PRK03646"
                     /db_xref="CDD:179622"
     Site            order(33,35,39,79,123,130,157,159,191..193,207..210,341)
                     /site_type="active"
                     /db_xref="CDD:143500"
     Site            order(33,35,39,79,159,191..192,207,209..210,341)
                     /site_type="other"
                     /note="pyridoxal 5'-phosphate (PLP) binding site [chemical
                     binding]"
                     /db_xref="CDD:143500"
     Site            order(35,39,130,159,341)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:143500"
     Site            order(35,253)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:143500"
     Site            order(240,243,249..250,252..254,267,272,278,300,302,339,
                     341..342,347,350)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:143500"
     CDS             1..356
                     /locus_tag="KPHS_33190"
                     /coded_by="complement(NC_016845.1:3302870..3303940)"
                     /transl_table=11
                     /db_xref="GeneID:11848342"
CONTIG      join(WP_002910887.1:1..356)
ORIGIN      
        1 mtrpvvasid llalrqnlqi vrraapgsrl wavvkanayg hgvarvwsal saadgfalln
       61 leeaillreq gwkgpillle gffhadelav ldqyrlttsv hsnwqikalq qaklrapldi
      121 ylkvnsgmnr lgfmpervht vwqqlraisn vgemtlmshf aeaenpqgiv epmrrieqaa
      181 egldcprsla nsaatlwhpe ahfdwvrpgi vlygaspsgq wqdiantglk pvmtlrseii
      241 gvqnlrpgea igygglyrtt qeqrigivac gyadgyprva psgtpvlvdg vrtttvgrvs
      301 mdmlavdltp cpqagigapv elwgkeikid dvaassgtvg yelmcalapr vpvvtl