5-methyltetrahydropteroyltriglutamate/homocysteine

LOCUS       YP_005227444             343 aa            linear   CON 02-JUN-2020
            S-methyltransferase [Klebsiella pneumoniae subsp. pneumoniae
            HS11286].
ACCESSION   YP_005227444
VERSION     YP_005227444.1
DBLINK      BioProject: PRJNA84387
            Assembly: GCF_000240185.1
DBSOURCE    REFSEQ: accession NC_016845.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae subsp. pneumoniae HS11286
  ORGANISM  Klebsiella pneumoniae subsp. pneumoniae HS11286
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 343)
  AUTHORS   Liu,P., Li,P., Jiang,X., Bi,D., Xie,Y., Tai,C., Deng,Z.,
            Rajakumar,K. and Ou,H.Y.
  TITLE     Complete genome sequence of Klebsiella pneumoniae subsp. pneumoniae
            HS11286, a multidrug-resistant strain isolated from human sputum
  JOURNAL   J. Bacteriol. 194 (7), 1841-1842 (2012)
   PUBMED   22408243
REFERENCE   2  (residues 1 to 343)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-FEB-2012) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 343)
  AUTHORS   Ou,H.-Y., Jiang,X., Liu,P. and Li,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-DEC-2011) State Key Laboratory of Microbial
            Metabolism, Shanghai Jiaotong University, 1954 Huashan Road,
            Shanghai 200030, China
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence is identical to AEW61842.
            RefSeq Category: Reference Genome
                        CLI: Clinical Isolate
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..343
                     /organism="Klebsiella pneumoniae subsp. pneumoniae
                     HS11286"
                     /strain="HS11286"
                     /sub_species="pneumoniae"
                     /db_xref="taxon:1125630"
     Protein         1..343
                     /product="5-
                     methyltetrahydropteroyltriglutamate/homocysteine
                     S-methyltransferase"
                     /calculated_mol_wt=38343
     Region          3..341
                     /region_name="PRK09121"
                     /note="methionine synthase"
                     /db_xref="CDD:181659"
     Site            order(10..12,63,69,176,178,211,213,312..313)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:239427"
     Site            order(93..95,140,180)
                     /site_type="active"
                     /note="THF binding site [active]"
                     /db_xref="CDD:239427"
     Site            order(211,213,253,312)
                     /site_type="other"
                     /note="zinc-binding site [ion binding]"
                     /db_xref="CDD:239427"
     CDS             1..343
                     /locus_tag="KPHS_31440"
                     /coded_by="complement(NC_016845.1:3131932..3132963)"
                     /transl_table=11
                     /db_xref="GeneID:11848165"
CONTIG      join(WP_002909005.1:1..343)
ORIGIN      
        1 mktwlptsta gslpkpswla qpetlwspwk lsseellagk rdalrlsldd qlragidivs
       61 dgeqtrqhfv ttfiehlsgv dfakreivki rnryeasvpt vvgaverqkp vfvedarylr
      121 qltsqpikwa lpgpmtmidt lydnhyksre klawefakil nqeakeleaa gvdiiqfdep
      181 afnvffdevn dwgiaalera teglkcetav hicygygika ntdwkktlgs ewrqyeeafp
      241 qlqkssldii slechnsrvp mdllelirgk kvmvgaidva shaietpeev agtlrkalaf
      301 vdadklypst ncgmaplprh vatgklhals agaeiirrel aak