2-ketoacid reductase [Klebsiella pneumoniae subsp. pneumoniae

LOCUS       YP_005226232             312 aa            linear   CON 02-JUN-2020
            HS11286].
ACCESSION   YP_005226232
VERSION     YP_005226232.1
DBLINK      BioProject: PRJNA84387
            Assembly: GCF_000240185.1
DBSOURCE    REFSEQ: accession NC_016845.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae subsp. pneumoniae HS11286
  ORGANISM  Klebsiella pneumoniae subsp. pneumoniae HS11286
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 312)
  AUTHORS   Liu,P., Li,P., Jiang,X., Bi,D., Xie,Y., Tai,C., Deng,Z.,
            Rajakumar,K. and Ou,H.Y.
  TITLE     Complete genome sequence of Klebsiella pneumoniae subsp. pneumoniae
            HS11286, a multidrug-resistant strain isolated from human sputum
  JOURNAL   J. Bacteriol. 194 (7), 1841-1842 (2012)
   PUBMED   22408243
REFERENCE   2  (residues 1 to 312)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-FEB-2012) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 312)
  AUTHORS   Ou,H.-Y., Jiang,X., Liu,P. and Li,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-DEC-2011) State Key Laboratory of Microbial
            Metabolism, Shanghai Jiaotong University, 1954 Huashan Road,
            Shanghai 200030, China
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence is identical to AEW60630.
            RefSeq Category: Reference Genome
                        CLI: Clinical Isolate
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..312
                     /organism="Klebsiella pneumoniae subsp. pneumoniae
                     HS11286"
                     /strain="HS11286"
                     /sub_species="pneumoniae"
                     /db_xref="taxon:1125630"
     Protein         1..312
                     /product="2-ketoacid reductase"
                     /calculated_mol_wt=35038
     Region          1..312
                     /region_name="ghrA"
                     /note="glyoxylate/hydroxypyruvate reductase GhrA;
                     PRK15469"
                     /db_xref="CDD:185366"
     Site            order(46,64..66,95,227,275)
                     /site_type="other"
                     /note="putative ligand binding site [chemical binding]"
                     /db_xref="CDD:240641"
     Site            order(65..66,89,95,99,143..147,165..168,170,197..199,
                     203..204,225..227,251..252,275,277..278,310)
                     /site_type="other"
                     /note="NAD binding site [chemical binding]"
                     /db_xref="CDD:240641"
     Site            order(98,100..102,104..105,108..109,112,114,117..118,
                     120..121,125..126,128,131,134,158,249,253,256..258,260,
                     264..265,267,270,272..274,276..277,281)
                     /site_type="other"
                     /note="dimerization interface [polypeptide binding]"
                     /db_xref="CDD:240641"
     CDS             1..312
                     /locus_tag="KPHS_19320"
                     /coded_by="NC_016845.1:1999692..2000630"
                     /transl_table=11
                     /db_xref="GeneID:11846950"
CONTIG      join(WP_002898938.1:1..312)
ORIGIN      
        1 meiifyhptf dtqywicele kqlpgarvre wkagdnrpad yalvwhppve mlqgralkav
       61 falgagvdsi lsklrdhpdm lplsiplfrl edtgmgrqmq eyavsqvlhw frrfddyqal
      121 klasrwqplp eyradeftvg imgagvlgak vaeslqpwgf plrvwsrsrk swpqvqsfag
      181 qaelgeflqg trvlinllpn taetagiinq tllaqlpdes yvlnlargvh vveedllaal
      241 nsgklkgaml dvfsreplpq esplwahprv amtphvaavt rpmeaityia etisrlerge
      301 pvsgqvdrqr gy